MASTL promotes cell contractility and motility through kinase-independent signaling

MASTL inhibition promotes mitotic catastrophe through PP2A activation to inhibit cancer growth and radioresistance in breast cancer cells

(2018) Yi Na Yoon et al.   BMC CANCER

MASTL overexpression promotes chromosome instability and metastasis in breast cancer

(2018) Samuel Rogers et al.   ONCOGENE

Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress

(2018) Jiska van der Reest et al.   Nature Communications

Identification of new inhibitors against human Great wall kinase using in silico approaches

(2018) Ummi Ammarah et al.   Scientific Reports

SRF'ing and SAP'ing – the role of MRTF proteins in cell migration

(2018) David Gau et al.   JOURNAL OF CELL SCIENCE

Thrombocytopenia-associated mutations in Ser/Thr kinase MASTL deregulate actin cytoskeletal dynamics in platelets

(2018) Begoña Hurtado et al.   JOURNAL OF CLINICAL INVESTIGATION

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Mitosis perturbation by MASTL depletion impairs the viability of thyroid tumor cells

(2018) Elena Cetti et al.   CANCER LETTERS

MRTF transcription and Ezrin-dependent plasma membrane blebbing are required for entotic invasion

(2017) Laura Soto Hinojosa et al.   JOURNAL OF CELL BIOLOGY

Actin assembly mechanisms at a glance

(2017) Klemens Rottner et al.   JOURNAL OF CELL SCIENCE

Ensa controls S-phase length by modulating Treslin levels

(2017) Sophie Charrasse et al.   Nature Communications

ROTS: An R package for reproducibility-optimized statistical testing

(2017) Tomi Suomi et al.   PLoS Computational Biology

Spatial regulation of greatwall by Cdk1 and PP2A-Tws in the cell cycle

(2016) Peng Wang et al.   CELL CYCLE

The master Greatwall kinase, a critical regulator of mitosis and meiosis

(2016) Suzanne Vigneron et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling

(2016) Guillaume Jacquemet et al.   Nature Communications

MASTL(Greatwall) regulates DNA damage responses by coordinating mitotic entry after checkpoint recovery and APC/C activation

(2016) Po Yee Wong et al.   Scientific Reports

The contractome - a systems view of actomyosin contractility in non-muscle cells

(2015) R. Zaidel-Bar et al.   JOURNAL OF CELL SCIENCE

Genome-wide siRNA Screen Identifies the Radiosensitizing Effect of Downregulation of MASTL and FOXM1 in NSCLC

(2015) R. Nagel et al.   MOLECULAR CANCER THERAPEUTICS

Forcing cells into shape: the mechanics of actomyosin contractility

(2015) Michael Murrell et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Greatwall promotes cell transformation by hyperactivating AKT in human malignancies

(2015) Jorge Vera et al.   eLife

The RhoGEF GEF-H1 Is Required for Oncogenic RAS Signaling via KSR-1

(2014) Jane Cullis et al.   CANCER CELL

Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts

(2014) C. Esnault et al.   GENES & DEVELOPMENT

GEF-H1 functions in apical constriction and cell intercalations and is essential for vertebrate neural tube closure

(2014) K. Itoh et al.   JOURNAL OF CELL SCIENCE

A systematic nomenclature for mammalian tropomyosin isoforms

(2014) Michael A. Geeves et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Force to Divide: Structural and Mechanical Requirements for Actomyosin Ring Contraction

(2013) Inês Mendes Pinto et al.   BIOPHYSICAL JOURNAL

A soft cortex is essential for asymmetric spindle positioning in mouse oocytes

(2013) Agathe Chaigne et al.   NATURE CELL BIOLOGY

GEF-H1 controls microtubule-dependent sensing of nucleic acids for antiviral host defenses

(2013) Hao-Sen Chiang et al.   NATURE IMMUNOLOGY

Functional Interaction of SCAI with the SWI/SNF Complex for Transcription and Tumor Cell Invasion

(2013) Camilla Kreßner et al.   PLoS One

Nuclear Actin Network Assembly by Formins Regulates the SRF Coactivator MAL

(2013) C. Baarlink et al.   SCIENCE

Hyperosmotic stress regulates the distribution and stability of myocardin-related transcription factor, a key modulator of the cytoskeleton

(2012) Donald L. Ly et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Role of RhoA-Specific Guanine Exchange Factors in Regulation of Endomitosis in Megakaryocytes

(2012) Yuan Gao et al.   DEVELOPMENTAL CELL

The Microtubule-Associated Rho Activating Factor GEF-H1 Interacts with Exocyst Complex to Regulate Vesicle Traffic

(2012) Ritu Pathak et al.   DEVELOPMENTAL CELL

Scanning angle interference microscopy reveals cell dynamics at the nanoscale

(2012) Matthew J Paszek et al.   NATURE METHODS

A Molecular Pathway for Myosin II Recruitment to Stress Fibers

(2011) Sari Tojkander et al.   CURRENT BIOLOGY

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins

(2011) Christophe Guilluy et al.   NATURE CELL BIOLOGY

MASTL is the human ortholog of Greatwall kinase that facilitates mitotic entry, anaphase and cytokinesis

(2010) Erik Voets et al.   CELL CYCLE

Myosin II contributes to cell-scale actin network treadmilling through network disassembly

(2010) Cyrus A. Wilson et al.   NATURE

Linking actin dynamics and gene transcription to drive cellular motile functions

(2010) Eric N. Olson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanics of cytokinesis in eukaryotes

(2009) Thomas D Pollard   CURRENT OPINION IN CELL BIOLOGY

Simple and rapid process for single cell micro-patterning

(2009) Ammar Azioune et al.   LAB ON A CHIP

Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis

(2009) Souhila Medjkane et al.   NATURE CELL BIOLOGY

The Universal Protein Resource (UniProt) in 2010

(2009)   NUCLEIC ACIDS RESEARCH

Actin, a Central Player in Cell Shape and Movement

(2009) T. D. Pollard et al.   SCIENCE

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

Moesin Controls Cortical Rigidity, Cell Rounding, and Spindle Morphogenesis during Mitosis

(2008) Patricia Kunda et al.   CURRENT BIOLOGY

Moesin and its activating kinase Slik are required for cortical stability and microtubule organization in mitotic cells

(2008) Sébastien Carreno et al.   JOURNAL OF CELL BIOLOGY

Mechanical forces facilitate actin polymerization at focal adhesions in a zyxin-dependent manner

(2008) H. Hirata et al.   JOURNAL OF CELL SCIENCE

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Model-based variance-stabilizing transformation for Illumina microarray data

(2008) Simon M. Lin et al.   NUCLEIC ACIDS RESEARCH

Cellular functions of GEF-H1, a microtubule-regulated Rho-GEF: is altered GEF-H1 activity a crucial determinant of disease pathogenesis?

(2008) Jörg Birkenfeld et al.   TRENDS IN CELL BIOLOGY