Hyperosmotic stress regulates the distribution and stability of myocardin-related transcription factor, a key modulator of the cytoskeleton

Myocardin-related transcription factor A regulates expression of Bok and Noxa and is involved in apoptotic signalling

(2012) Dmitry Shaposhnikov et al.   CELL CYCLE

Microtubules regulate GEF-H1 in response to extracellular matrix stiffness

(2012) Jessica N. Heck et al.   MOLECULAR BIOLOGY OF THE CELL

Stress- and Rho-activated ZO-1-associated nucleic acid binding protein binding to p21 mRNA mediates stabilization, translation, and cell survival

(2012) M. Nie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Ins and Outs of the Epithelial to Mesenchymal Transition in Health and Disease

(2011) M. Angela Nieto   Annual Review of Cell and Developmental Biology

Epithelial-Mesenchymal Interactions in Pulmonary Fibrosis

(2011) Harold A. Chapman   Annual Review of Physiology

TGF-β-induced mesenchymal transition of MS-1 endothelial cells requires Smad-dependent cooperative activation of Rho signals and MRTF-A

(2011) Hajime Mihira et al.   JOURNAL OF BIOCHEMISTRY

The Src Family Kinase Fyn Mediates Hyperosmolarity-induced Mrp2 and Bsep Retrieval from Canalicular Membrane

(2011) Miriam Cantore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyperosmotic stress strongly potentiates serum response factor (SRF)-dependent transcriptional activity in ehrlich lettré ascites cells through a mechanism involving p38 mitogen-activated protein kinase

(2011) Andrej Gorbatenko et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Scar wars: mapping the fate of epithelial–mesenchymal–myofibroblast transition

(2011) Susan E. Quaggin et al.   KIDNEY INTERNATIONAL

MicroRNA-200c Represses Migration and Invasion of Breast Cancer Cells by Targeting Actin-Regulatory Proteins FHOD1 and PPM1F

(2011) S. Jurmeister et al.   MOLECULAR AND CELLULAR BIOLOGY

β-Catenin and Smad3 regulate the activity and stability of myocardin-related transcription factor during epithelial–myofibroblast transition

(2011) Emmanuel Charbonney et al.   MOLECULAR BIOLOGY OF THE CELL

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins

(2011) Christophe Guilluy et al.   NATURE CELL BIOLOGY

Rac1/osmosensing scaffold for MEKK3 contributes via phospholipase C- 1 to activation of the osmoprotective transcription factor NFAT5

(2011) X. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular signal-regulated kinase and GEF-H1 mediate depolarization-induced Rho activation and paracellular permeability increase

(2010) Faiza Waheed et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mechanotransduction by GEF-H1 as a novel mechanism of ventilator-induced vascular endothelial permeability

(2010) Anna A. Birukova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Myocardin-Related Transcription Factor-A Controls Myofibroblast Activation and Fibrosis in Response to Myocardial Infarction

(2010) Eric M. Small et al.   CIRCULATION RESEARCH

Fate-determining mechanisms in epithelial–myofibroblast transition: major inhibitory role for Smad3

(2010) András Masszi et al.   JOURNAL OF CELL BIOLOGY

The RhoA Activator GEF-H1/Lfc Is a Transforming Growth Factor-β Target Gene and Effector That Regulates α-Smooth Muscle Actin Expression and Cell Migration

(2010) Anna Tsapara et al.   MOLECULAR BIOLOGY OF THE CELL

Linking actin dynamics and gene transcription to drive cellular motile functions

(2010) Eric N. Olson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stress induced gene expression: a direct role for MAPKAP kinases in transcriptional activation of immediate early genes

(2010) N. Ronkina et al.   NUCLEIC ACIDS RESEARCH

GEF-H1 Mediates Tumor Necrosis Factor-α-induced Rho Activation and Myosin Phosphorylation

(2009) Eli Kakiashvili et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Physiology of Cell Volume Regulation in Vertebrates

(2009) Else K. Hoffmann et al.   PHYSIOLOGICAL REVIEWS

Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response

(2008) Ana C. P. Thirone et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

ERK1/2 phosphorylate GEF-H1 to enhance its guanine nucleotide exchange activity toward RhoA

(2008) Shuh-hei Fujishiro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL

(2008) Stephane Mouilleron et al.   EMBO JOURNAL

Epithelial cell-cell contacts regulate SRF-mediated transcription via Rac-actin-MAL signalling

(2008) S. Busche et al.   JOURNAL OF CELL SCIENCE

Serum-Induced Phosphorylation of the Serum Response Factor Coactivator MKL1 by the Extracellular Signal-Regulated Kinase 1/2 Pathway Inhibits Its Nuclear Localization

(2008) S. Muehlich et al.   MOLECULAR AND CELLULAR BIOLOGY

GEF-H1 Couples Nocodazole-induced Microtubule Disassembly to Cell Contractility via RhoA

(2008) Yuan-Chen Chang et al.   MOLECULAR BIOLOGY OF THE CELL

MKP-1 inhibits high NaCl-induced activation of p38 but does not inhibit the activation of TonEBP/OREBP: Opposite roles of p38  and p38 

(2008) X. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications

(2007) Maria Rasmussen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY