Oocytes mount a noncanonical DNA damage response involving APC-Cdh1–mediated proteolysis

The importance of DNA repair for maintaining oocyte quality in response to anti-cancer treatments, environmental toxins and maternal ageing

(2018) Amy L Winship et al.   HUMAN REPRODUCTION UPDATE

Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63

(2018) Marcel Tuppi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility

(2018) Quynh-Nhu Nguyen et al.   Cell Death & Disease

Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63

(2018) Marcel Tuppi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cdk1 inactivation induces post-anaphase-onset spindle migration and membrane protrusion required for extreme asymmetry in mouse oocytes

(2018) Zhe Wei et al.   Nature Communications

Pharmacological Inhibition of the DNA Damage Checkpoint Prevents Radiation-Induced Oocyte Death

(2017) Vera D. Rinaldi et al.   GENETICS

Regulation of chromosome segregation in oocytes and the cellular basis for female meiotic errors

(2017) Jessica Greaney et al.   HUMAN REPRODUCTION UPDATE

Molecular Mechanisms Responsible for Increased Vulnerability of the Ageing Oocyte to Oxidative Damage

(2017) Bettina P. Mihalas et al.   Oxidative Medicine and Cellular Longevity

Pharmacological Inhibition of the DNA Damage Checkpoint Prevents Radiation-Induced Oocyte Death

(2017) Vera D. Rinaldi et al.   GENETICS

DNA damage response during mouse oocyte maturation

(2016) Alexandra Mayer et al.   CELL CYCLE

Inhibitory phosphorylation of Cdk1 mediates prolonged prophase I arrest in female germ cells and is essential for female reproductive lifespan

(2016) Deepak Adhikari et al.   CELL RESEARCH

DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age

(2015) Petros Marangos et al.   Nature Communications

DNA damage induces a meiotic arrest in mouse oocytes mediated by the spindle assembly checkpoint

(2015) Josie K. Collins et al.   Nature Communications

Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase

(2014) Erik Müllers et al.   CELL CYCLE

Transient Activation of p53 in G2 Phase Is Sufficient to Induce Senescence

(2014) Lenno Krenning et al.   MOLECULAR CELL

Reversal of Female Infertility by Chk2 Ablation Reveals the Oocyte DNA Damage Checkpoint Pathway

(2014) E. Bolcun-Filas et al.   SCIENCE

Hec1-Dependent Cyclin B2 Stabilization Regulates the G2-M Transition and Early Prometaphase in Mouse Oocytes

(2013) Liming Gui et al.   DEVELOPMENTAL CELL

The regulation of maturation promoting factor during prophase I arrest and meiotic entry in mammalian oocytes

(2013) Deepak Adhikari et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The APC/C in female mammalian meiosis I

(2013) Hayden Homer   REPRODUCTION

Impairment of BRCA1-Related DNA Double-Strand Break Repair Leads to Ovarian Aging in Mice and Humans

(2013) S. Titus et al.   Science Translational Medicine

Senataxin Plays an Essential Role with DNA Damage Response Proteins in Meiotic Recombination and Gene Silencing

(2013) Olivier J. Becherel et al.   PLoS Genetics

The DNA damage response in mammalian oocytes

(2013) John Carroll et al.   Frontiers in Genetics

Oocytes Progress beyond Prophase in the Presence of DNA Damage

(2012) Petros Marangos et al.   CURRENT BIOLOGY

Spindle assembly checkpoint signalling is uncoupled from chromosomal position in mouse oocytes

(2012) L. Gui et al.   DEVELOPMENT

DNA Damage-Induced Primordial Follicle Oocyte Apoptosis and Loss of Fertility Require TAp63-Mediated Induction of Puma and Noxa

(2012) Jeffrey B. Kerr et al.   MOLECULAR CELL

The APC/C activator FZR1 coordinates the timing of meiotic resumption during prophase I arrest in mammalian oocytes

(2011) J. E. Holt et al.   DEVELOPMENT

Oxidative Damage Increases and Antioxidant Gene Expression Decreases with Aging in the Mouse Ovary

(2010) J. Lim et al.   BIOLOGY OF REPRODUCTION

Progressive Activation of CyclinB1-Cdk1 Coordinates Entry to Mitosis

(2010) Olivier Gavet et al.   DEVELOPMENTAL CELL

Understanding follicle growth in vivo

(2010) O. Oktem et al.   HUMAN REPRODUCTION

Prophase I arrest and progression to metaphase I in mouse oocytes: comparison of resumption of meiosis and recovery from G2-arrest in somatic cells

(2010) P. Solc et al.   MOLECULAR HUMAN REPRODUCTION

p53- and p21-dependent premature APC/C–Cdh1 activation in G2 is part of the long-term response to genotoxic stress

(2010) L Wiebusch et al.   ONCOGENE

Enhancing Survival of Mouse Oocytes Following Chemotherapy or Aging by Targeting Bax and Rad51

(2010) Loro L. Kujjo et al.   PLoS One

Contribution of culture media to oxidative stress and its effect on human oocytes

(2010) Francisco Javier Martín-Romero et al.   REPRODUCTIVE BIOMEDICINE ONLINE

CDC14B Acts Through FZR1 (CDH1) to Prevent Meiotic Maturation of Mouse Oocytes1

(2009) Karen Schindler et al.   BIOLOGY OF REPRODUCTION

Inhibition of the c-Abl–TAp63 pathway protects mouse oocytes from chemotherapy-induced death

(2009) Stefania Gonfloni et al.   NATURE MEDICINE

A Spindle Assembly Checkpoint Protein Functions in Prophase I Arrest and Prometaphase Progression

(2009) H. Homer et al.   SCIENCE

The Cdc14B-Cdh1-Plk1 Axis Controls the G2 DNA-Damage-Response Checkpoint

(2008) Florian Bassermann et al.   CELL

Securin regulates entry into M-phase by modulating the stability of cyclin B

(2008) Petros Marangos et al.   NATURE CELL BIOLOGY