Host lipid droplets: An important source of lipids salvaged by the intracellular parasite Toxoplasma gondii

The Membrane Phospholipid Binding Protein Annexin A2 Promotes Phagocytosis and Nonlytic Exocytosis ofCryptococcus neoformansand Impacts Survival in Fungal Infection

(2016) Sabriya Stukes et al.   JOURNAL OF IMMUNOLOGY

Host Lipid Bodies as Platforms for Intracellular Survival of Protozoan Parasites

(2016) Daniel A. M. Toledo et al.   Frontiers in Immunology

Expanding Roles for Lipid Droplets

(2015) Michael A. Welte   CURRENT BIOLOGY

Lipid droplet–organelle interactions: emerging roles in lipid metabolism

(2015) Antonio Daniel Barbosa et al.   CURRENT OPINION IN CELL BIOLOGY

The small GTPase Rab7 as a central regulator of hepatocellular lipophagy

(2015) Barbara Schroeder et al.   HEPATOLOGY

A Lipolytic Lecithin:Cholesterol Acyltransferase Secreted byToxoplasmaFacilitates Parasite Replication and Egress

(2015) Viviana Pszenny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chlamydia trachomatis Infection Leads to Defined Alterations to the Lipid Droplet Proteome in Epithelial Cells

(2015) Hector Alex Saka et al.   PLoS One

Intravacuolar Membranes Regulate CD8 T Cell Recognition of Membrane-Bound Toxoplasma gondii Protective Antigen

(2015) Jodie Lopez et al.   Cell Reports

Lipid droplet formation in response to oleic acid in Huh-7 cells is mediated by the fatty acid receptor FFAR4

(2014) A. Rohwedder et al.   JOURNAL OF CELL SCIENCE

Culture of mouse peritoneal macrophages with mouse serum induces lipid bodies that associate with the parasitophorous vacuole and decrease their microbicidal capacity against Toxoplasma gondii

(2014) Laura Azeredo Miranda Mota et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

The Intriguing Ultrastructure of Lipid Body Organelles Within Activated Macrophages

(2014) Felipe F. Dias et al.   MICROSCOPY AND MICROANALYSIS

Toxoplasma gondii-skeletal muscle cells interaction increases lipid droplet biogenesis and positively modulates the production of IL-12, IFN-g and PGE2

(2014) Alessandra F Gomes et al.   Parasites & Vectors

Toxoplasma Effector MAF1 Mediates Recruitment of Host Mitochondria and Impacts the Host Response

(2014) Lena Pernas et al.   PLOS BIOLOGY

BCKDH: The Missing Link in Apicomplexan Mitochondrial Metabolism Is Required for Full Virulence of Toxoplasma gondii and Plasmodium berghei

(2014) Rebecca D. Oppenheim et al.   PLoS Pathogens

Cell-to-Cell Heterogeneity in Lipid Droplets Suggests a Mechanism to Reduce Lipotoxicity

(2013) Albert Herms et al.   CURRENT BIOLOGY

Exploitation of auxotrophies and metabolic defects in Toxoplasma as therapeutic approaches

(2013) Isabelle Coppens   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains

(2013) Adam Kassan et al.   JOURNAL OF CELL BIOLOGY

Toxoplasma gondii salvages sphingolipids from the host Golgi through the rerouting of selected Rab vesicles to the parasitophorous vacuole

(2013) Julia D. Romano et al.   MOLECULAR BIOLOGY OF THE CELL

Characterization of a second sterol-esterifying enzyme inToxoplasmahighlights the importance of cholesterol storage pathways for the parasite

(2013) Bao Lige et al.   MOLECULAR MICROBIOLOGY

Development of small-molecule inhibitors targeting adipose triglyceride lipase

(2013) Nicole Mayer et al.   Nature Chemical Biology

Targeting lipid biosynthesis and salvage in apicomplexan parasites for improved chemotherapies

(2013) Isabelle Coppens   NATURE REVIEWS MICROBIOLOGY

Lipid synthesis in protozoan parasites: A comparison between kinetoplastids and apicomplexans

(2013) Srinivasan Ramakrishnan et al.   PROGRESS IN LIPID RESEARCH

Lipid Body–Phagosome Interaction in Macrophages during Infectious Diseases: Host Defense or Pathogen Survival Strategy?

(2012) Rossana C. N. Melo et al.   PLoS Pathogens

Emerging Roles for Lipid Droplets in Immunity and Host-Pathogen Interactions

(2011) Hector Alex Saka et al.   Annual Review of Cell and Developmental Biology

Evidence for Host Cells as the Major Contributor of Lipids in the Intravacuolar Network of Toxoplasma-Infected Cells

(2011) Carolina E. Caffaro et al.   EUKARYOTIC CELL

Distinct regulation of stearoyl-CoA desaturase 1 gene expression by cis and trans C18:1 fatty acids in human aortic smooth muscle cells

(2011) M. Minville-Walz et al.   Genes and Nutrition

Host Cell Lipid Bodies Triggered by Trypanosoma cruzi Infection and Enhanced by the Uptake of Apoptotic Cells Are Associated With Prostaglandin E2 Generation and Increased Parasite Growth

(2011) Heloisa D’Avila et al.   JOURNAL OF INFECTIOUS DISEASES

DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes

(2011) Charles A. Harris et al.   JOURNAL OF LIPID RESEARCH

Not Just Fat: The Structure and Function of the Lipid Droplet

(2011) T. Fujimoto et al.   Cold Spring Harbor Perspectives in Biology

Structural and Functional Characterization of the Recombinant Human Mitochondrial Trifunctional Protein

(2010) Benjamin Fould et al.   BIOCHEMISTRY

Versatility in the acquisition of energy and carbon sources by the Apicomplexa

(2010) Valerie Polonais et al.   BIOLOGY OF THE CELL

Modulation of lipid droplets by Mycobacterium leprae in Schwann cells: a putative mechanism for host lipid acquisition and bacterial survival in phagosomes

(2010) Katherine A. Mattos et al.   CELLULAR MICROBIOLOGY

Dihydronaphthalene-Fused Boron-Dipyrromethene (BODIPY) Dyes: Insight into the Electronic and Conformational Tuning Modes of BODIPY Fluorophores

(2010) Yan-Wei Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Coordinate Control of Host Centrosome Position, Organelle Distribution, and Migratory Response byToxoplasma gondiivia Host mTORC2

(2010) Yubao Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores

(2009) Perry E. Bickel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lipid homeostasis, lipotoxicity and the metabolic syndrome

(2009) Roger H. Unger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Structural insight into function and regulation of carnitine palmitoyltransferase

(2009) Arne C. Rufer et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Lipid droplets at a glance

(2009) Y. Guo et al.   JOURNAL OF CELL SCIENCE

Dengue Virus Capsid Protein Usurps Lipid Droplets for Viral Particle Formation

(2009) Marcelo M. Samsa et al.   PLoS Pathogens

The Endoplasmic Reticulum Enzyme DGAT2 Is Found in Mitochondria-associated Membranes and Has a Mitochondrial Targeting Signal That Promotes Its Association with Mitochondria

(2008) Scot J. Stone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytoplasmic lipid droplets are translocated into the lumen of the Chlamydia trachomatis parasitophorous vacuole

(2008) J. L. Cocchiaro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging of Lipid Biosynthesis: How a Neutral Lipid Enters Lipid Droplets

(2008) Lars Kuerschner et al.   TRAFFIC

Foamy Macrophages from Tuberculous Patients' Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence

(2008) Pascale Peyron et al.   PLoS Pathogens