One-Step Derivatization of Reducing Oligosaccharides for Rapid and Live-Cell-Compatible Chelation-Assisted CuAAC Conjugation

Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-SelectiveSalmonellaO-Antigen Glycoconjugate Vaccines

(2015) Giuseppe Stefanetti et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA display of glycoconjugates to emulate oligomeric interactions of glycans

(2015) Alexandre Novoa et al.   Beilstein Journal of Organic Chemistry

Site-Specific Glycoconjugation of Protein via Bioorthogonal Tetrazine Cycloaddition with a Genetically Encoded trans-Cyclooctene or Bicyclononyne

(2015) Takuya Machida et al.   BIOCONJUGATE CHEMISTRY

Advances in Chemical Protein Modification

(2015) Omar Boutureira et al.   CHEMICAL REVIEWS

Bioorthogonal Reactions for Labeling Proteins

(2014) Kathrin Lang et al.   ACS Chemical Biology

A LecA Ligand Identified from a Galactoside-Conjugate Array Inhibits Host Cell Invasion byPseudomonas aeruginosa

(2014) Alexandre Novoa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Chelating Azides for Efficient Click Conjugation Reactions in Complex Media

(2014) Valentina Bevilacqua et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protecting-Group-Free One-Pot Synthesis of Glycoconjugates Directly from Reducing Sugars

(2014) David Lim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Monitoring Dynamic Glycosylation in Vivo Using Supersensitive Click Chemistry

(2014) Hao Jiang et al.   BIOCONJUGATE CHEMISTRY

Chemoenzymatic Fc Glycosylation via Engineered Aldehyde Tags

(2014) Elizabeth L. Smith et al.   BIOCONJUGATE CHEMISTRY

PNA-Encoded Synthesis (PES) of a 10 000-Member Hetero-Glycoconjugate Library and Microarray Analysis of Diverse Lectins

(2014) Alexandre Novoa et al.   CHEMBIOCHEM

Directed Evolution of Multivalent Glycopeptides Tightly Recognized by HIV Antibody 2G12

(2014) Satoru Horiya et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High Temperature SELMA: Evolution of DNA-Supported Oligomannose Clusters Which Are Tightly Recognized by HIV bnAb 2G12

(2014) J. Sebastian Temme et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of DIBAC analogues with excellent SPAAC rate constants

(2014) Marjoke F. Debets et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Selective chemical protein modification

(2014) Christopher D. Spicer et al.   Nature Communications

Solid phase synthesis of glycopeptides using Shoda's activation of unprotected carbohydrates

(2013) Alexandre Novoa et al.   CHEMICAL COMMUNICATIONS

Glycotherapy: New Advances Inspire a Reemergence of Glycans in Medicine

(2013) Jason E. Hudak et al.   CHEMISTRY & BIOLOGY

Glycosylation: impact, control and improvement during therapeutic protein production

(2013) Ana Rita Costa et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Protein conjugation with genetically encoded unnatural amino acids

(2013) Chan Hyuk Kim et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Rationally Designed Short Polyisoprenol-Linked PglB Substrates for Engineered Polypeptide and Protein N-Glycosylation

(2013) Feng Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective affinity-based probe for oncogenic kinases suitable for live cell imaging

(2013) Claudio Zambaldo et al.   Chemical Science

Synthesis of a well-defined glycoconjugate vaccine by a tyrosine-selective conjugation strategy

(2013) Qi-Ying Hu et al.   Chemical Science

Synthetically defined glycoprotein vaccines: current status and future directions

(2013) Roberto Adamo et al.   Chemical Science

Fast, Cell-Compatible Click Chemistry with Copper-Chelating Azides for Biomolecular Labeling

(2012) Chayasith Uttamapinant et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Glycoclusters on oligonucleotide and PNA scaffolds: synthesis and applications

(2012) Nicolas Spinelli et al.   CHEMICAL SOCIETY REVIEWS

Site-Selective Glycosylation of Hemoglobin with Variable Molecular Weight Oligosaccharides: Potential Alternative to PEGylation

(2012) Thomas J. Styslinger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reactivity of Biarylazacyclooctynones in Copper-Free Click Chemistry

(2012) Chelsea G. Gordon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Virus-like glycodendrinanoparticles displaying quasi-equivalent nested polyvalency upon glycoprotein platforms potently block viral infection

(2012) Renato Ribeiro-Viana et al.   Nature Communications

A “Tag-and-Modify” Approach to Site-Selective Protein Modification

(2011) Justin M. Chalker et al.   ACCOUNTS OF CHEMICAL RESEARCH

Multivalent Glycocluster Design through Directed Evolution

(2011) Iain S. MacPherson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Coordinated Synthesis and Conjugation Strategy for the Preparation of Homogeneous Glycoconjugate Vaccine Candidates

(2011) Elizabeth J. Grayson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Dehydrative Pyridylthio-Glycosidation of Unprotected Sugars in Aqueous Media Using 2-Chloro-1,3-dimethylimidazolinium Chloride as a Condensing Agent

(2011) Naoki Yoshida et al.   Chemistry-An Asian Journal

Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag

(2011) Jason E. Hudak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Readily Accessible Bicyclononynes for Bioorthogonal Labeling and Three-Dimensional Imaging of Living Cells

(2010) Jan Dommerholt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chelation-Assisted, Copper(II)-Acetate-Accelerated Azide−Alkyne Cycloaddition

(2010) Gui-Chao Kuang et al.   JOURNAL OF ORGANIC CHEMISTRY

Rapid Cu-Free Click Chemistry with Readily Synthesized Biarylazacyclooctynones

(2010) John C. Jewett et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thiyl Glycosylation of Olefinic Proteins: S-Linked Glycoconjugate Synthesis

(2009) Nicola Floyd et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Analysis and Optimization of Copper-Catalyzed Azide–Alkyne Cycloaddition for Bioconjugation

(2009) Vu Hong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Threefold Glycosylated Proteins using Click Chemistry and Genetically Encoded Unnatural Amino Acids

(2009) Emine Kaya et al.   CHEMBIOCHEM

One-step conversion of unprotected sugars to β-glycosyl azides using 2-chloroimidazolinium salt in aqueous solution

(2009) Tomonari Tanaka et al.   CHEMICAL COMMUNICATIONS

Direct Transformation of Unprotected Sugars to Aryl 1-Thio-β-glycosides in Aqueous Media Using 2-Chloro-1,3-dimethylimidazolinium Chloride

(2009) Tomonari Tanaka et al.   CHEMISTRY LETTERS

Genetic Encoding and Labeling of Aliphatic Azides and Alkynes in Recombinant Proteinsviaa Pyrrolysyl-tRNA Synthetase/tRNACUAPair and Click Chemistry

(2009) Duy P. Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct synthesis of 1,6-anhydro sugars from unprotected glycopyranoses by using 2-chloro-1,3-dimethylimidazolinium chloride

(2009) Tomonari Tanaka et al.   TETRAHEDRON LETTERS

Cu-Catalyzed Azide−Alkyne Cycloaddition

(2008) Morten Meldal et al.   CHEMICAL REVIEWS

Facile Conversion of Cysteine and Alkyl Cysteines to Dehydroalanine on Protein Surfaces: Versatile and Switchable Access to Functionalized Proteins

(2008) Gonçalo J. L. Bernardes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY