Development and validation of a UHPLC-MS/MS method for quantification of the prodrug remdesivir and its metabolite GS-441524: a tool for clinical pharmacokinetics of SARS-CoV-2/COVID-19 and Ebola virus disease

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

(2020) Manli Wang et al.   CELL RESEARCH

Learning from the Past: Possible Urgent Prevention and Treatment Options for Severe Acute Respiratory Infections Caused by 2019‐nCoV

(2020) Jared S. Morse et al.   CHEMBIOCHEM

Drug treatment options for the 2019-new coronavirus (2019-nCoV)

(2020) Hongzhou Lu   BioScience Trends

A Randomized, Controlled Trial of Ebola Virus Disease Therapeutics

(2019) Sabue Mulangu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

(2018) Maria L. Agostini et al.   mBio

LC-MS application for therapeutic drug monitoring in alternative matrices

(2018) Valeria Avataneo et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses

(2017) Dustin Siegel et al.   JOURNAL OF MEDICINAL CHEMISTRY

UHPLC–MS/MS method with sample dilution to test therapeutic adherence through quantification of ten antihypertensive drugs in urine samples

(2017) Amedeo De Nicolò et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses

(2017) Timothy P. Sheahan et al.   Science Translational Medicine

Matrix effect management in liquid chromatography mass spectrometry: the internal standard normalized matrix effect

(2017) Amedeo De Nicolò et al.   Bioanalysis

Evaluation of irreversible protein thermal inactivation caused by breakage of disulphide bonds using methanethiosulphonate

(2017) Junichiro Futami et al.   Scientific Reports

UHPLC–MS/MS method with automated on-line solid phase extraction for the quantification of entecavir in peripheral blood mononuclear cells of HBV+ patients

(2016) Amedeo De Nicolò et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

(2016) Travis K. Warren et al.   NATURE

Therapeutic drug monitoring of antiretroviral drugs in HIV-infected patients

(2016) Baralee Punyawudho et al.   Expert Review of Clinical Pharmacology

CLSI C62-A: A New Standard for Clinical Mass Spectrometry

(2015) K. L. Lynch   CLINICAL CHEMISTRY

Contribution of Disulfide Bridges to the Thermostability of a Type A Feruloyl Esterase from Aspergillus usamii

(2015) Xin Yin et al.   PLoS One

Development and validation of a useful UPLC–MS/MS method for quantification of total and phosphorylated-ribavirin in peripheral blood mononuclear cells of HCV+ patients

(2013) Danilo Agnesod et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Development and validation of a useful HPLC–UV method for quantification of total and phosphorylated-ribavirin in blood and erythrocytes of HCV+ patients

(2012) Antonio D’Avolio et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Therapeutic drug monitoring in highly active antiretroviral therapy

(2010) Xia Liu et al.   Expert Opinion On Drug Safety

Major pitfalls in the measurement of artemisinin derivatives in plasma in clinical studies

(2008) N. Lindegardh et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES