Lessons Learned from Somatic Cell Nuclear Transfer

Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer

(2018) Zhen Liu et al.   CELL

Compensating human subjects providing oocytes for stem cell research: 9-year experience and outcomes

(2018) L. Zakarin Safier et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Genomic instability during reprogramming by nuclear transfer is DNA replication dependent

(2017) Gloryn Chia et al.   NATURE CELL BIOLOGY

Epigenetic modification with trichostatin A does not correct specific errors of somatic cell nuclear transfer at the transcriptomic level; highlighting the non-random nature of oocyte-mediated reprogramming errors

(2016) Sayyed Morteza Hosseini et al.   BMC GENOMICS

Human somatic cell nuclear transfer and reproductive cloning: an Ethics Committee opinion

(2016) Judith Daar et al.   FERTILITY AND STERILITY

Concise Review: Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer: A Horse in the Race?

(2016) Don P. Wolf et al.   STEM CELLS

Epigenetic reprogramming in mammalian species after SCNT-based cloning

(2016) Heiner Niemann   THERIOGENOLOGY

A New, Dynamic Era for Somatic Cell Nuclear Transfer?

(2016) Pasqualino Loi et al.   TRENDS IN BIOTECHNOLOGY

Identification of key factors conquering developmental arrest of somatic cell cloned embryos by combining embryo biopsy and single-cell sequencing

(2016) Wenqiang Liu et al.   Cell Discovery

Histone Demethylase Expression Enhances Human Somatic Cell Nuclear Transfer Efficiency and Promotes Derivation of Pluripotent Stem Cells

(2015) Young Gie Chung et al.   Cell Stem Cell

Improved Development of Somatic Cell Cloned Mouse Embryos by Vitamin C and Latrunculin A

(2015) Anna Mallol et al.   PLoS One

Embryonic Development following Somatic Cell Nuclear Transfer Impeded by Persisting Histone Methylation

(2014) Shogo Matoba et al.   CELL

Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells

(2014) Mitsutoshi Yamada et al.   NATURE

Therapeutic potential of somatic cell nuclear transfer for degenerative disease caused by mitochondrial DNA mutations

(2014) Gareth D. Greggains et al.   Scientific Reports

Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer

(2013) Masahito Tachibana et al.   CELL

Epigenetics of cellular reprogramming

(2013) Raga Krishnakumar et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Reshaping the transcriptional frontier: Epigenetics and somatic cell nuclear transfer

(2013) Charles R. Long et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Latrunculin A Can Improve the Birth Rate of Cloned Mice and Simplify the Nuclear Transfer Protocol by Gently Inhibiting Actin Polymerization1

(2012) Yukari Terashita et al.   BIOLOGY OF REPRODUCTION

Epigenetic Status and Full-term Development of Bovine Cloned Embryos Treated with Trichostatin A

(2012) Ken Sawai et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Transient JMJD2B-Mediated Reduction of H3K9me3 Levels Improves Reprogramming of Embryonic Stem Cells into Cloned Embryos

(2012) J. Antony et al.   MOLECULAR AND CELLULAR BIOLOGY

Recent advancements in cloning by somatic cell nuclear transfer

(2012) A. Ogura et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Offspring from Oocytes Derived from in Vitro Primordial Germ Cell-like Cells in Mice

(2012) K. Hayashi et al.   SCIENCE

Reconstitution of the Mouse Germ Cell Specification Pathway in Culture by Pluripotent Stem Cells

(2011) Katsuhiko Hayashi et al.   CELL

Impracticality of Egg Donor Recruitment in the Absence of Compensation

(2011) Dieter Egli et al.   Cell Stem Cell

Moving Human SCNT Research Forward Ethically

(2011) Insoo Hyun   Cell Stem Cell

Isolation and In Vitro Characterization of Putative Porcine Embryonic Stem Cells from Cloned Embryos Treated with Trichostatin A

(2011) Ivan Vassiliev et al.   Cellular Reprogramming

Comparison of potency between histone deacetylase inhibitors trichostatin A and valproic acid on enhancing in vitro development of porcine somatic cell nuclear transfer embryos

(2011) Young June Kim et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Cloning of non-human primates: the road "less traveled by"

(2011) Michelle L. Sparman et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Human oocytes reprogram somatic cells to a pluripotent state

(2011) Scott Noggle et al.   NATURE

RNAi-mediated knockdown of Xist can rescue the impaired postimplantation development of cloned mouse embryos

(2011) S. Matoba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reprogramming within hours following nuclear transfer into mouse but not human zygotes

(2011) Dieter Egli et al.   Nature Communications

Inhibition of Class IIb Histone Deacetylase Significantly Improves Cloning Efficiency in Mice1

(2010) Tetsuo Ono et al.   BIOLOGY OF REPRODUCTION

Effect of epigenetic regulation during swine embryogenesis and on cloning by nuclear transfer

(2010) Jianguo Zhao et al.   CELL AND TISSUE RESEARCH

Cloning Mice and Men: Prohibiting the Use of iPS Cells for Human Reproductive Cloning

(2010) Bernard Lo et al.   Cell Stem Cell

Histone Deacetylase Inhibitors Improve In Vitro and In Vivo Developmental Competence of Somatic Cell Nuclear Transfer Porcine Embryos

(2010) Jianguo Zhao et al.   Cellular Reprogramming

Rapid Elimination of the Histone Variant MacroH2A from Somatic Cell Heterochromatin after Nuclear Transfer

(2010) Ching-Chien Chang et al.   Cellular Reprogramming

Somatic Nucleus Reprogramming Is Significantly Improved bym-Carboxycinnamic Acid Bishydroxamide, a Histone Deacetylase Inhibitor

(2010) Xiangpeng Dai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Developmental Ability of Miniature Pig Embryos Cloned with Mesenchymal Stem Cells

(2010) Sung-Lim LEE et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

How to Improve the Success Rate of Mouse Cloning Technology

(2010) Nguyen Van THUAN et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Treatment with a Histone Deacetylase Inhibitor after Nuclear Transfer Improves the Preimplantation Development of Cloned Bovine Embryos

(2010) Satoshi AKAGI et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Somatic cell nuclear transfer efficiency: How can it be improved through nuclear remodeling and reprogramming?

(2010) Kristin M. Whitworth et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Chromosome transfer in mature oocytes

(2010) Masahito Tachibana et al.   Nature Protocols

Treatment of ovine oocytes with caffeine increases the accessibility of DNase I to the donor chromatin and reduces apoptosis in somatic cell nuclear transfer embryos

(2010) Inchul Choi et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Impeding Xist Expression from the Active X Chromosome Improves Mouse Somatic Cell Nuclear Transfer

(2010) K. Inoue et al.   SCIENCE

Production of cloned calves by combination treatment of both donor cells and early cloned embryos with 5-aza-2/-deoxycytidine and trichostatin A

(2010) Y.S. Wang et al.   THERIOGENOLOGY

Significant Improvement in Cloning Efficiency of an Inbred Miniature Pig by Histone Deacetylase Inhibitor Treatment after Somatic Cell Nuclear Transfer1

(2009) Jianguo Zhao et al.   BIOLOGY OF REPRODUCTION

Mitochondrial gene replacement in primate offspring and embryonic stem cells

(2009) Masahito Tachibana et al.   NATURE

The histone deacetylase inhibitor scriptaid enhances nascent mRNA production and rescues full-term development in cloned inbred mice

(2009) Nguyen Van Thuan et al.   REPRODUCTION

Epigenetic Reprogramming by Somatic Cell Nuclear Transfer in Primates

(2009) Michelle Sparman et al.   STEM CELLS

The developmental potential of mouse somatic cell nuclear-transferred oocytes treated with trichostatin A and 5-aza-2′-deoxycytidine

(2009) Yuta Tsuji et al.   ZYGOTE

Live Birth of Somatic Cell-Cloned Rabbits following Trichostatin A Treatment and Cotransfer of Parthenogenetic Embryos

(2009) Qinggang Meng et al.   Cloning Stem Cells

A Comparative Study on the Efficiency of Two Enucleation Methods in Pig Somatic Cell Nuclear Transfer: Effects of the Squeezing and the Aspiration Methods

(2008) Eunsong Lee et al.   ANIMAL BIOTECHNOLOGY

Trichostatin A (TSA) improves the development of rabbit-rabbit intraspecies cloned embryos, but not rabbit-human interspecies cloned embryos

(2008) Li-Hong Shi et al.   DEVELOPMENTAL DYNAMICS

Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

(2008) P. A.C. Cloos et al.   GENES & DEVELOPMENT

Tolerance strategies for stem-cell-based therapies

(2008) Ann P. Chidgey et al.   NATURE

Ultrastructure of Placental Hyperplasia in Mice: Comparison of Placental Phenotypes with Three Different Etiologies

(2008) N. Wakisaka et al.   PLACENTA

Development of Human Cloned Blastocysts Following Somatic Cell Nuclear Transfer with Adult Fibroblasts

(2008) Andrew J. French et al.   STEM CELLS

Increased pre-implantation development of cloned bovine embryos treated with 5-aza-2′-deoxycytidine and trichostatin A

(2008) X. Ding et al.   THERIOGENOLOGY

High in vitro development after somatic cell nuclear transfer and trichostatin A treatment of reconstructed porcine embryos

(2008) J. Li et al.   THERIOGENOLOGY

Trichostatin A Improves Histone Acetylation in Bovine Somatic Cell Nuclear Transfer Early Embryos

(2008) Amy E. Iager et al.   Cloning Stem Cells