Shared Genomic and Proteomic Contribution of Amyloid and Tau Protein Characteristic of Alzheimer’s Disease to Brain Ischemia

Substantiation for the Use of Curcumin during the Development of Neurodegeneration after Brain Ischemia

(2020) Marzena Ułamek-Kozioł et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Proteomic and Genomic Changes in Tau Protein, Which Are Associated with Alzheimer’s Disease after Ischemia-Reperfusion Brain Injury

(2020) Marzena Ułamek-Kozioł et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structure Based Design and Molecular Docking Studies for Phosphorylated Tau Inhibitors in Alzheimer’s Disease

(2019) Jangampalli Pradeepkiran et al.   Cells

Protective effects of BACE1 inhibitory ligand molecules against amyloid beta-induced synaptic and mitochondrial toxicities in Alzheimer’s disease

(2019) Jangampalli Adi Pradeepkiran et al.   HUMAN MOLECULAR GENETICS

Neuroinflammation as a target for treatment of stroke using mesenchymal stem cells and extracellular vesicles

(2019) Sylwia Dabrowska et al.   Journal of Neuroinflammation

Expression of the Tau Protein and Amyloid Protein Precursor Processing Genes in the CA3 Area of the Hippocampus in the Ischemic Model of Alzheimer’s Disease in the Rat

(2019) Ryszard Pluta et al.   MOLECULAR NEUROBIOLOGY

Tau as a potential therapeutic target for ischemic stroke

(2019) Xin Chen et al.   Aging-US

Dysregulation of Autophagy, Mitophagy, and Apoptosis Genes in the CA3 Region of the Hippocampus in the Ischemic Model of Alzheimer’s Disease in the Rat

(2019) Marzena Ułamek-Kozioł et al.   JOURNAL OF ALZHEIMERS DISEASE

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Mechanism of Tau Hyperphosphorylation Involving Lysosomal Enzyme Asparagine Endopeptidase in a Mouse Model of Brain Ischemia

(2018) Gustavo Basurto-Islas et al.   JOURNAL OF ALZHEIMERS DISEASE

Association of Induced Hyperhomocysteinemia with Alzheimer’s Disease-Like Neurodegeneration in Rat Cortical Neurons After Global Ischemia-Reperfusion Injury

(2018) Maria Kovalska et al.   NEUROCHEMICAL RESEARCH

Tau pathology and neurochemical changes associated with memory dysfunction in an optimised murine model of global cerebral ischaemia - A potential model for vascular dementia?

(2018) Sabah Khan et al.   NEUROCHEMISTRY INTERNATIONAL

Oxidative stress and DNA damage after cerebral ischemia: Potential therapeutic targets to repair the genome and improve stroke recovery

(2018) Peiying Li et al.   NEUROPHARMACOLOGY

Ischemic tau protein gene induction as an additional key factor driving development of Alzheimer’s phenotype changes in CA1 area of hippocampus in an ischemic model of Alzheimer’s disease

(2018) Ryszard Pluta et al.   Pharmacological Reports

Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease

(2018) Fuyuki Kametani et al.   Frontiers in Neuroscience

Traumatic Brain Injury and Alzheimer's Disease: The Cerebrovascular Link

(2018) Jaime Ramos-Cejudo et al.   EBioMedicine

Tau Protein Dysfunction after Brain Ischemia

(2018) Ryszard Pluta et al.   JOURNAL OF ALZHEIMERS DISEASE

Pharmacophore-based models for therapeutic drugs against phosphorylated tau in Alzheimer’s disease

(2018) Jangampalli Adi Pradeepkiran et al.   DRUG DISCOVERY TODAY

Dysregulation of Alzheimer’s disease-related genes and proteins following cardiac arrest

(2017) Ryszard Pluta et al.   FOLIA NEUROPATHOLOGICA

Re-imagining Alzheimer's disease - the diminishing importance of amyloid and a glimpse of what lies ahead

(2017) Kai-Hei Tse et al.   JOURNAL OF NEUROCHEMISTRY

Hypoxia/ischemia activate processing of Amyloid Precursor Protein: impact of vascular dysfunction in the pathogenesis of Alzheimer's disease

(2017) Antero Salminen et al.   JOURNAL OF NEUROCHEMISTRY

Tau-mediated iron export prevents ferroptotic damage after ischemic stroke

(2017) Q-z Tuo et al.   MOLECULAR PSYCHIATRY

Autophagy, mitophagy and apoptotic gene changes in the hippocampal CA1 area in a rat ischemic model of Alzheimer’s disease

(2017) Marzena Ułamek-Kozioł et al.   Pharmacological Reports

Tau exacerbates excitotoxic brain damage in an animal model of stroke

(2017) Mian Bi et al.   Nature Communications

Tau Proteins Cross the Blood-Brain Barrier

(2016) William A. Banks et al.   JOURNAL OF ALZHEIMERS DISEASE

Dysregulation of Autophagy, Mitophagy, and Apoptotic Genes in the Medial Temporal Lobe Cortex in an Ischemic Model of Alzheimer’s Disease

(2016) Marzena Ułamek-Kozioł et al.   JOURNAL OF ALZHEIMERS DISEASE

Discrepancy in Expression of β-Secretase and Amyloid-β Protein Precursor in Alzheimer-Related Genes in the Rat Medial Temporal Lobe Cortex Following Transient Global Brain Ischemia

(2016) Ryszard Pluta et al.   JOURNAL OF ALZHEIMERS DISEASE

Modifications of tau protein after cerebral ischemia and reperfusion in rats are similar to those occurring in Alzheimer’s disease – Hyperphosphorylation and cleavage of 4- and 3-repeat tau

(2016) Hiroki Fujii et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Alzheimer-associated presenilin 2 gene is dysregulated in rat medial temporal lobe cortex after complete brain ischemia due to cardiac arrest

(2016) Ryszard Pluta et al.   Pharmacological Reports

Calpains and neuronal damage in the ischemic brain: The swiss knife in synaptic injury

(2016) Michele Curcio et al.   PROGRESS IN NEUROBIOLOGY

Serum Aβ is Predictive for Short-Term Neurological Deficits After Acute Ischemic Stroke

(2015) Yu-Hui Liu et al.   NEUROTOXICITY RESEARCH

Effect of Cardiac Arrest on Cognitive Impairment and Hippocampal Plasticity in Middle-Aged Rats

(2015) Charles H. Cohan et al.   PLoS One

Influence of Amyloid-β on Cognitive Decline After Stroke/Transient Ischemic Attack

(2015) Wenyan Liu et al.   STROKE

Chronic cerebral hypoperfusion causes decrease of O-GlcNAcylation, hyperphosphorylation of tau and behavioral deficits in mice

(2014) Yang Zhao et al.   Frontiers in Aging Neuroscience

Global Cerebral Ischemia: Synaptic and Cognitive Dysfunction

(2013) Jake T. Neumann et al.   CURRENT DRUG TARGETS

Ischemia signalling to Alzheimer-related genes

(2013) Ryszard Pluta et al.   FOLIA NEUROPATHOLOGICA

Sporadic Alzheimer’s Disease Begins as Episodes of Brain Ischemia and Ischemically Dysregulated Alzheimer’s Disease Genes

(2013) Ryszard Pluta et al.   MOLECULAR NEUROBIOLOGY

Damage to White Matter Pathways in Subacute and Chronic Spatial Neglect: A Group Study and 2 Single-Case Studies with Complete Virtual "In Vivo" Tractography Dissection

(2012) M. Thiebaut de Schotten et al.   CEREBRAL CORTEX

Cerebral Hypoperfusion During Carotid Artery Stenosis can Lead to Cognitive Deficits that may be Independent of White Matter Lesion Load

(2012) Martin Scherr et al.   CURRENT NEUROVASCULAR RESEARCH

Brain Ischemia Activates β- and γ-Secretase Cleavage of Amyloid Precursor Protein: Significance in Sporadic Alzheimer’s Disease

(2012) Ryszard Pluta et al.   MOLECULAR NEUROBIOLOGY

Remodeling of synapses in the CA1 area of the hippocampus after transient global ischemia

(2012) Y.-W. Ruan et al.   NEUROSCIENCE

Tau proteins in serum predict neurological outcome after hypoxic brain injury from cardiac arrest: Results of a pilot study

(2012) Jeffrey Randall et al.   RESUSCITATION

Plasma tau protein in comatose patients after cardiac arrest treated with therapeutic hypothermia

(2011) E. MÖRTBERG et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Impaired conditioned emotional response and object recognition are concomitant to neuronal damage in the amygdala and perirhinal cortex in middle-aged ischemic rats

(2011) Patricia Barra de la Tremblaye et al.   BEHAVIOURAL BRAIN RESEARCH

Tau elevations in the brain extracellular space correlate with reduced amyloid-β levels and predict adverse clinical outcomes after severe traumatic brain injury

(2011) Sandra Magnoni et al.   BRAIN

Cellular markers of neuroinflammation and neurogenesis after ischemic brain injury in the long-term survival rat model

(2011) Vera Sekeljic et al.   Brain Structure & Function

Cognitive Impairment with Vascular Impairment and Degeneration

(2011) Ryszard Pluta et al.   CURRENT NEUROVASCULAR RESEARCH

Compounding artefacts with uncertainty, and an amyloid cascade hypothesis that is ‘too big to fail’

(2011) Rudy J Castellani et al.   JOURNAL OF PATHOLOGY

Cerebral ischemia aggravates cognitive impairment in a rat model of Alzheimer's disease

(2011) Jing Li et al.   LIFE SCIENCES

Hypoxia Due to Cardiac Arrest Induces a Time-Dependent Increase in Serum Amyloid β Levels in Humans

(2011) Henrik Zetterberg et al.   PLoS One

Ischemic Cerebral Damage

(2011) Jeannette Hofmeijer et al.   STROKE

Transient brain ischemia due to cardiac arrest causes irreversible long-lasting cognitive injury

(2010) Anna Kiryk et al.   BEHAVIOURAL BRAIN RESEARCH

Matrix metalloproteinase-9 contributes to the increase of tau protein in serum during acute ischemic stroke

(2010) Jacek Kurzepa et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Does Serum Tau Protein Predict the Outcome of Patients with Ischemic Stroke?

(2010) Joanna Bielewicz et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Alzheimer's Mechanisms in Ischemic Brain Degeneration

(2009) Ryszard Pluta et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Alterations in mRNA expression of BACE1, cathepsin B, and glutaminyl cyclase in mice ischemic brain

(2009) Jian-tao Ye et al.   NEUROREPORT

Panax Notoginseng Burk Attenuates Impairment of Learning and Memory Functions and Increases ED1, BDNF and β-Secretase Immunoreactive Cells in Chronic Stage Ischemia-Reperfusion Injured Rats

(2008) Chin-Min Chuang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Chronic cerebral hypoperfusion induced by right unilateral common carotid artery occlusion causes delayed white matter lesions and cognitive impairment in adult mice

(2007) Kaichi Yoshizaki et al.   EXPERIMENTAL NEUROLOGY