Hypoxia, Inflammation and Necrosis as Determinants of Glioblastoma Cancer Stem Cells Progression

Hypoxia/pseudohypoxia‐mediated activation of hypoxia‐inducible factor‐1α in cancer

(2019) Yoshihiro Hayashi et al.   CANCER SCIENCE

Musashi-1 Enhances Glioblastoma Migration by Promoting ICAM1 Translation

(2019) Jang-Chun Lin et al.   NEOPLASIA

The Tumor Microenvironment Innately Modulates Cancer Progression

(2019) Dominique C. Hinshaw et al.   CANCER RESEARCH

ROS mediated EGFR/MEK/ERK/HIF-1α Loop Regulates Glucose metabolism in pancreatic cancer

(2018) Gang Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Potential impact of invasive surgical procedures on primary tumor growth and metastasis

(2018) Maria Alieva et al.   CLINICAL & EXPERIMENTAL METASTASIS

Metabolic Heterogeneity Evidenced by MRS among Patient-Derived Glioblastoma Multiforme Stem-Like Cells Accounts for Cell Clustering and Different Responses to Drugs

(2018) Sveva Grande et al.   Stem Cells International

RAGE and Its Ligands: Molecular Interplay Between Glycation, Inflammation, and Hallmarks of Cancer—a Review

(2018) Gowri Palanissami et al.   Hormones & Cancer

Danger-Associated Molecular Patterns (DAMPs): the Derivatives and Triggers of Inflammation

(2018) Seema Patel   CURRENT ALLERGY AND ASTHMA REPORTS

The Different Routes to Metastasis via Hypoxia-Regulated Programs

(2018) Ana Rita Nobre et al.   TRENDS IN CELL BIOLOGY

EZH2, HIF-1, and Their Inhibitors: An Overview on Pediatric Cancers

(2018) Marco Papale et al.   Frontiers in Pediatrics

The clinical value of patient-derived glioblastoma tumorspheres in predicting treatment response

(2017) Quintino Giorgio D’Alessandris et al.   NEURO-ONCOLOGY

Preventing inflammation inhibits biopsy-mediated changes in tumor cell behavior

(2017) Maria Alieva et al.   Scientific Reports

Cancer Stem Cells: Basic Concepts and Therapeutic Implications

(2016) Dany Nassar et al.   Annual Review of Pathology-Mechanisms of Disease

Up-regulation of microRNA-16 in Glioblastoma Inhibits the Function of Endothelial Cells and Tumor Angiogenesis by Targeting Bmi-1

(2016) Fanfan Chen et al.   Anti-Cancer Agents in Medicinal Chemistry

The hypoxic microenvironment: A determinant of cancer stem cell evolution

(2016) Amancio Carnero et al.   BIOESSAYS

Damage-associated molecular patterns in cancer: a double-edged sword

(2016) C Hernandez et al.   ONCOGENE

Targeting of RAGE-ligand signaling impairs breast cancer cell invasion and metastasis

(2016) T Kwak et al.   ONCOGENE

The Interplay of Reactive Oxygen Species, Hypoxia, Inflammation, and Sirtuins in Cancer Initiation and Progression

(2016) Marco Tafani et al.   Oxidative Medicine and Cellular Longevity

Glioblastoma multiforme: Effect of hypoxia and hypoxia inducible factors on therapeutic approaches

(2016) Wen-Juan Huang et al.   Oncology Letters

Targeting hexokinase 2 enhances response to radio-chemotherapy in glioblastoma

(2016) Alenoush Vartanian et al.   Oncotarget

Metabolic/Proteomic Signature Defines Two Glioblastoma Subtypes With Different Clinical Outcome

(2016) G. Marziali et al.   Scientific Reports

DAMPs, ageing, and cancer: The ‘DAMP Hypothesis’

(2015) Jin Huang et al.   AGEING RESEARCH REVIEWS

Effect of chronic hypoxia on RAGE and its soluble forms in lungs and plasma of mice

(2015) P. Gopal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The role of S100 proteins and their receptor RAGE in pancreatic cancer

(2015) Estelle Leclerc et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1α–ZEB1 axis

(2015) Justin V. Joseph et al.   CANCER LETTERS

Regulation of Hypoxia-Inducible Factor-1a by Reactive Oxygen Species : New Developments in an Old Debate

(2015) Shahrzad Movafagh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Systemic inflammation and microglial activation: systematic review of animal experiments

(2015) Inge C.M. Hoogland et al.   Journal of Neuroinflammation

MicroRNA-566 modulates vascular endothelial growth factor by targeting Von Hippel-Landau in human glioblastoma in vitro and in vivo

(2015) BING XIAO et al.   Molecular Medicine Reports

Glial fibrillary acidic protein: from intermediate filament assembly and gliosis to neurobiomarker

(2015) Zhihui Yang et al.   TRENDS IN NEUROSCIENCES

One Special Question to Start with: Can HIF/NFkB be a Target in Inflammation?

(2015) Matteo Russo et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Receptor for AGEs (RAGE) as Mediator of NF-kB Pathway Activation in Neuroinflammation and Oxidative Stress

(2014) Julio Tobon-Velasco et al.   CNS & Neurological Disorders-Drug Targets

Microenvironment and tumor cell plasticity: An easy way out

(2013) Maria Letizia Taddei et al.   CANCER LETTERS

Dysfunctional endothelial cells directly stimulate cancer inflammation and metastasis

(2013) Joseph W. Franses et al.   INTERNATIONAL JOURNAL OF CANCER

HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations

(2013) Gregg L. Semenza   JOURNAL OF CLINICAL INVESTIGATION

Ovarian cancer stem cells: Molecular concepts and relevance as therapeutic targets

(2013) Nuzhat Ahmed et al.   MOLECULAR ASPECTS OF MEDICINE

1H NMR detects different metabolic profiles in glioblastoma stem-like cells

(2013) Laura Guidoni et al.   NMR IN BIOMEDICINE

Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells

(2012) Shin Hamada et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Emerging insights into the molecular and cellular basis of glioblastoma

(2012) G. P. Dunn et al.   GENES & DEVELOPMENT

Hypoxia-inducible factors as key regulators of tumor inflammation

(2012) Soulafa Mamlouk et al.   INTERNATIONAL JOURNAL OF CANCER

The transcription of the alarmin cytokine interleukin-1 alpha is controlled by hypoxia inducible factors 1 and 2 alpha in hypoxic cells

(2012) Peleg Rider et al.   Frontiers in Immunology

Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-κB

(2011) Marco Tafani et al.   CARCINOGENESIS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Cancer Stem Cells and Colorectal Cancer: An Overview

(2011) Anand S. Srivastava et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastoma

(2011) Marco Tafani et al.   Journal of Neuroinflammation

Circulating tumour cells, their role in metastasis and their clinical utility in lung cancer

(2011) John D. O’Flaherty et al.   LUNG CANCER

Metabolic management of brain cancer

(2010) Thomas N. Seyfried et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Up-regulation of pro-inflammatory genes as adaptation to hypoxia in MCF-7 cells and in human mammary invasive carcinoma microenvironment

(2010) Marco Tafani et al.   CANCER SCIENCE

Inflammation and oncogenesis: a vicious connection

(2009) Sergei I Grivennikov et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization

(2009) K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxygen homeostasis

(2009) Gregg L. Semenza   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Cancer Stem Cell Analysis and Clinical Outcome in Patients with Glioblastoma Multiforme

(2008) R. Pallini et al.   CLINICAL CANCER RESEARCH

Prostate cancer stem cells

(2008) SH Lang et al.   JOURNAL OF PATHOLOGY

Digoxin and other cardiac glycosides inhibit HIF-1  synthesis and block tumor growth

(2008) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA