Advances on Chelation and Chelator Metal Complexes in Medicine

THE HISTORY OF DEFERIPRONE (L1) AND THE COMPLETE TREATMENT OF IRON OVERLOAD IN THALASSAEMIA

(2020) George J Kontoghiorghes et al.   Mediterranean Journal of Hematology and Infectious Diseases

Prospects for the introduction of targeted antioxidant drugs for the prevention and treatment of diseases related to free radical pathology

(2019) George J Kontoghiorghes et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Metals and Alzheimer’s Disease: How Far Have We Come in the Clinic?

(2018) Paul A. Adlard et al.   JOURNAL OF ALZHEIMERS DISEASE

Iron promotes oxidative cell death caused by bisretinoids of retina

(2018) Keiko Ueda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deferiprone inhibits iron overload-induced tissue factor bearing endothelial microparticle generation by inhibition oxidative stress induced mitochondrial injury, and apoptosis

(2018) Shing Chan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Biocompatibility Studies of Gadolinium Complexes with Iminodiacetic Acid Derivatives

(2018) Magdalena Markowicz-Piasecka et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Gadolinium deposition in the brain: summary of evidence and recommendations

(2017) Vikas Gulani et al.   LANCET NEUROLOGY

The therapeutic potential of iron-targeting gallium compounds in human disease: From basic research to clinical application

(2017) Christopher R. Chitambar   PHARMACOLOGICAL RESEARCH

Brain iron chelation by deferiprone in a phase 2 randomised double-blinded placebo controlled clinical trial in Parkinson’s disease

(2017) Antonio Martin-Bastida et al.   Scientific Reports

Iron deposition is associated with differential macrophage infiltration and therapeutic response to iron chelation in prostate cancer

(2017) Avigdor Leftin et al.   Scientific Reports

Mitochondria and Cancer

(2016) Sejal Vyas et al.   CELL

The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs

(2016) Timothy C. Johnstone et al.   CHEMICAL REVIEWS

Efficacy and safety of iron-chelation therapy with deferoxamine, deferiprone, and deferasirox for the treatment of iron-loaded patients with non-transfusion-dependent thalassemia syndromes

(2016) George J. Kontoghiorghes et al.   Drug Design Development and Therapy

Kill or cure: Misuse of chelation therapy for human diseases

(2015) Guido Crisponi et al.   COORDINATION CHEMISTRY REVIEWS

Ferric Maltol Is Effective in Correcting Iron Deficiency Anemia in Patients with Inflammatory Bowel Disease

(2015) Christoph Gasche et al.   INFLAMMATORY BOWEL DISEASES

Phytochelators Intended for Clinical Use in Iron Overload, Other Diseases of Iron Imbalance and Free Radical Pathology

(2015) Christina Kontoghiorghe et al.   MOLECULES

Characterization of the Neuroprotective Potential of Derivatives of the Iron Chelating Drug Deferiprone

(2015) Pamela Maher et al.   NEUROCHEMICAL RESEARCH

Targeting cancer by binding iron: Dissecting cellular signaling pathways

(2015) Goldie Y.L. Lui et al.   Oncotarget

Oxidative Stress and Mitochondrial Dysfunction across Broad-Ranging Pathologies: Toward Mitochondria-Targeted Clinical Strategies

(2014) Giovanni Pagano et al.   Oxidative Medicine and Cellular Longevity

Reactivity of food phenols with iron and copper ions: binding, dioxygen activation and oxidation mechanisms

(2014) Ezzohra Nkhili et al.   Food & Function

Potential clinical applications of chelating drugs in diseases targeting transferrin-bound iron and other metals

(2013) Christina N Kontoghiorghe et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Liver iron and serum ferritin levels are misleading for estimating cardiac, pancreatic, splenic and total body iron load in thalassemia patients: factors influencing the heterogenic distribution of excess storage iron in organs as identified by MRI T2*

(2012) Annita Kolnagou et al.   TOXICOLOGY MECHANISMS AND METHODS

Hydroxyurea: a key player in cancer chemotherapy

(2011) Kapish Madaan et al.   Expert Review of Anticancer Therapy

Iron-related MRI images in patients with pantothenate kinase-associated neurodegeneration (PKAN) treated with deferiprone: Results of a phase II pilot trial

(2011) Giovanna Zorzi et al.   MOVEMENT DISORDERS

A Review of the Antioxidant Mechanisms of Polyphenol Compounds Related to Iron Binding

(2009) Nathan R. Perron et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Iron availability and infection

(2008) Eugene D. Weinberg   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Regression of symptoms after selective iron chelation therapy in a case of neurodegeneration with brain iron accumulation

(2008) Gian Luca Forni et al.   MOVEMENT DISORDERS