The ESX-1 Virulence Factors Downregulate miR-147-3p in Mycobacterium marinum-Infected Macrophages

Mycobacterium marinum down-regulates miR-148a in macrophages in an EsxA-dependent manner

(2019) Haichong Wu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Effects of membrane lipid composition on Mycobacterium tuberculosis EsxA membrane insertion: A dual play of fluidity and charge

(2019) Supriyo Ray et al.   TUBERCULOSIS

Polarly Localized EccE1 Is Required for ESX-1 Function and Stabilization of ESX-1 Membrane Proteins in Mycobacterium tuberculosis

(2019) Paloma Soler-Arnedo et al.   JOURNAL OF BACTERIOLOGY

The Mycobacterium marinum ESX-1 system mediates phagosomal permeabilization and type I interferon production via separable mechanisms

(2019) Julia Lienard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WHO global progress report on tuberculosis elimination

(2019) Emilia Harding   Lancet Respiratory Medicine

miRNAs in immune responses to Mycobacterium tuberculosis infection

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MiR-1178 regulates mycobacterial survival and inflammatory responses in Mycobacterium tuberculosis-infected macrophages partly via TLR4

(2018) Ge Shi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mycobacterial ESX-1 secretion system mediates host cell lysis through bacterium contact-dependent gross membrane disruptions

(2017) William H. Conrad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early Secreted Antigenic Target of 6-kDa of Mycobacterium tuberculosis Stimulates IL-6 Production by Macrophages through Activation of STAT3

(2017) Bock-Gie Jung et al.   Scientific Reports

Mycobacterium avium MAV2052 protein induces apoptosis in murine macrophage cells through Toll-like receptor 4

(2016) Kang-In Lee et al.   APOPTOSIS

MIR144* inhibits antimicrobial responses against Mycobacterium tuberculosis in human monocytes and macrophages by targeting the autophagy protein DRAM2

(2016) Jin Kyung Kim et al.   Autophagy

Characterization of differential pore-forming activities of ESAT-6 proteins fromMycobacterium tuberculosisandMycobacterium smegmatis

(2016) Xiuli Peng et al.   FEBS LETTERS

Mechanism of ESAT-6 membrane interaction and its roles in pathogenesis of Mycobacterium tuberculosis

(2016) Xiuli Peng et al.   TOXICON

EsxA membrane-permeabilizing activity plays a key role in mycobacterial cytosolic translocation and virulence: effects of single-residue mutations at glutamine 5

(2016) Qi Zhang et al.   Scientific Reports

MicroRNA let-7 Modulates the Immune Response to Mycobacterium tuberculosis Infection via Control of A20, an Inhibitor of the NF-κB Pathway

(2015) Manish Kumar et al.   Cell Host & Microbe

Mycobacterium tuberculosisRpfE promotes simultaneous Th1- and Th17-type T-cell immunity via TLR4-dependent maturation of dendritic cells

(2015) Han-Gyu Choi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Characterization ofMycobacterium tuberculosisEsxA Membrane Insertion

(2015) Yue Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-155 knockout mice are susceptible to Mycobacterium tuberculosis infection

(2015) Hiroki Iwai et al.   TUBERCULOSIS

Cytosolic Access of Mycobacterium tuberculosis: Critical Impact of Phagosomal Acidification Control and Demonstration of Occurrence In Vivo

(2015) Roxane Simeone et al.   PLoS Pathogens

Correlation of Phenotypic Profiles Using Targeted Proteomics Identifies Mycobacterial Esx-1 Substrates

(2014) Matthew M. Champion et al.   JOURNAL OF PROTEOME RESEARCH

WXG100 Protein Superfamily Consists of Three Subfamilies and Exhibits an α-Helical C-Terminal Conserved Residue Pattern

(2014) Christian Poulsen et al.   PLoS One

Immune Subversion by Mycobacterium tuberculosis through CCR5 Mediated Signaling: Involvement of IL-10

(2014) Shibali Das et al.   PLoS One

Pro- and anti-inflammatory cytokines in tuberculosis: A two-edged sword in TB pathogenesis

(2014) Marilena Paola Etna et al.   SEMINARS IN IMMUNOLOGY

microRNAs in mycobacterial disease: friend or foe?

(2014) Manali D. Mehta et al.   Frontiers in Genetics

Oxidative Stress and MicroRNAs in Vascular Diseases

(2013) Alessandra Magenta et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of Interleukin 6 in Innate Immunity to Mycobacterium tuberculosis Infection

(2013) Alejandra N. Martinez et al.   JOURNAL OF INFECTIOUS DISEASES

Increased Cytokines Response in Patients with Tuberculosis Complicated with Chronic Obstructive Pulmonary Disease

(2013) Shenjie Tang et al.   PLoS One

Screening and Identification of Six Serum microRNAs as Novel Potential Combination Biomarkers for Pulmonary Tuberculosis Diagnosis

(2013) Xing Zhang et al.   PLoS One

The RD1 locus in theMycobacterium tuberculosisgenome contributes to the maturation and secretion of IL-1α from infected macrophages through the elevation of cytoplasmic calcium levels and calpain activation

(2013) Ruili Yang et al.   Pathogens and Disease

Changes in the immune and endocrine responses of patients with pulmonary tuberculosis undergoing specific treatment

(2012) Bettina Bongiovanni et al.   Annals of the New York Academy of Sciences

Altered serum microRNAs as biomarkers for the early diagnosis of pulmonary tuberculosis infection

(2012) Yuhua Qi et al.   BMC INFECTIOUS DISEASES

MicroRNAs are dynamically regulated and play an important role in LPS-induced lung injury

(2012) Zhi-Gang Cai et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria

(2012) Diane Houben et al.   CELLULAR MICROBIOLOGY

Identification of a novel role of ESAT-6-dependent miR-155 induction during infection of macrophages withMycobacterium tuberculosis

(2012) Ranjeet Kumar et al.   CELLULAR MICROBIOLOGY

Mycobacterium tuberculosis Rv0652 stimulates production of tumour necrosis factor and monocytes chemoattractant protein-1 in macrophages through the Toll-like receptor 4 pathway

(2012) Kwangwook Kim et al.   IMMUNOLOGY

Mycobacterium tuberculosisESAT-6 Exhibits a Unique Membrane-interacting Activity That Is Not Found in Its Ortholog from Non-pathogenicMycobacterium smegmatis

(2012) Joaquin De Leon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered microRNA expression levels in mononuclear cells of patients with pulmonary and pleural tuberculosis and their relation with components of the immune response

(2012) Silvana V. Spinelli et al.   MOLECULAR IMMUNOLOGY

The Cluster of miR-143 and miR-145 Affects the Risk for Esophageal Squamous Cell Carcinoma through Co-Regulating Fascin Homolog 1

(2012) Ran Liu et al.   PLoS One

Altered microRNA Signatures in Sputum of Patients with Active Pulmonary Tuberculosis

(2012) Zhengjun Yi et al.   PLoS One

Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death

(2012) Roxane Simeone et al.   PLoS Pathogens

Improved mycobacterial protein production using a Mycobacterium smegmatis groEL1ΔC expression strain

(2011) Elke E Noens et al.   BMC BIOTECHNOLOGY

Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis

(2011) Ka-Wing Wong et al.   CELLULAR MICROBIOLOGY

TheMycobacterium tuberculosisEarly Secreted Antigenic Target of 6 kDa Inhibits T Cell Interferon-γ Production through the p38 Mitogen-activated Protein Kinase Pathway

(2011) Hui Peng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circulating MicroRNAs in Patients with Active Pulmonary Tuberculosis

(2011) Y. Fu et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ

(2011) Feng Ma et al.   NATURE IMMUNOLOGY

Integrated MicroRNA-mRNA-Analysis of Human Monocyte Derived Macrophages upon Mycobacterium avium subsp. hominissuis Infection

(2011) Jutta Sharbati et al.   PLoS One

A Multifaceted Analysis of Immune-Endocrine-Metabolic Alterations in Patients with Pulmonary Tuberculosis

(2011) Natalia Santucci et al.   PLoS One

Comparative miRNA Expression Profiles in Individuals with Latent and Active Tuberculosis

(2011) Chuan Wang et al.   PLoS One

Innate immune responses to M. tuberculosis infection

(2011) Krishnamurthy Natarajan et al.   TUBERCULOSIS

Immune regulatory activities of early secreted antigenic target of 6-kD protein of Mycobacterium tuberculosis and implications for tuberculosis vaccine design

(2011) Buka Samten et al.   TUBERCULOSIS

Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome

(2010) Bibhuti B. Mishra et al.   CELLULAR MICROBIOLOGY

Stoichiometric protein complex formation and over-expression using the prokaryotic native operon structure

(2010) Christian Poulsen et al.   FEBS LETTERS

Human gene expression profiles of susceptibility and resistance in tuberculosis

(2010) J Maertzdorf et al.   GENES AND IMMUNITY

Cell-Mediated Immune Responses in Tuberculosis

(2009) Andrea M. Cooper   Annual Review of Immunology

MicroRNAs: Novel regulators of immunity

(2009) Claudia Carissimi et al.   AUTOIMMUNITY REVIEWS

Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation

(2009) A R R Forrest et al.   LEUKEMIA

miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses

(2009) G. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection

(2008) Ingrid C. Koo et al.   CELLULAR MICROBIOLOGY

Evidence for Pore Formation in Host Cell Membranes by ESX-1-Secreted ESAT-6 and Its Role in Mycobacterium marinum Escape from the Vacuole

(2008) J. Smith et al.   INFECTION AND IMMUNITY