The RD1 locus in theMycobacterium tuberculosisgenome contributes to the maturation and secretion of IL-1α from infected macrophages through the elevation of cytoplasmic calcium levels and calpain activation

Intracellular Interleukin-1 Receptor 2 Binding Prevents Cleavage and Activity of Interleukin-1α, Controlling Necrosis-Induced Sterile Inflammation

(2013) Yue Zheng et al.   IMMUNITY

Roles and underlying mechanisms of ESAT-6 in the context of Mycobacterium tuberculosis–host interaction from a systems biology perspective

(2012) Xiaowen Yu et al.   CELLULAR SIGNALLING

Inflammasome Activators Induce Interleukin-1α Secretion via Distinct Pathways with Differential Requirement for the Protease Function of Caspase-1

(2012) Olaf Groß et al.   IMMUNITY

Early Secreted Antigenic Target of 6-kDa Protein of Mycobacterium tuberculosis Primes Dendritic Cells To Stimulate Th17 and Inhibit Th1 Immune Responses

(2012) X. Wang et al.   JOURNAL OF IMMUNOLOGY

Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis

(2011) Ka-Wing Wong et al.   CELLULAR MICROBIOLOGY

Innate and Adaptive Interferons Suppress IL-1α and IL-1β Production by Distinct Pulmonary Myeloid Subsets during Mycobacterium tuberculosis Infection

(2011) Katrin D. Mayer-Barber et al.   IMMUNITY

Mycobacterial Secretion Systems ESX-1 and ESX-5 Play Distinct Roles in Host Cell Death and Inflammasome Activation

(2011) A. M. Abdallah et al.   JOURNAL OF IMMUNOLOGY

Calpastatin, an endogenous calpain-inhibitor protein, regulates the cleavage of the Cdk5 activator p35 to p25

(2011) Ko Sato et al.   JOURNAL OF NEUROCHEMISTRY

Inflammasome activation and IL-1  target IL-1  for secretion as opposed to surface expression

(2011) A. Fettelschoss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome

(2010) Bibhuti B. Mishra et al.   CELLULAR MICROBIOLOGY

Protein export systems ofMycobacterium tuberculosis: novel targets for drug development?

(2010) Meghan E Feltcher et al.   Future Microbiology

Listeriolysin O-Dependent Bacterial Entry into the Cytoplasm Is Required for Calpain Activation and Interleukin-1  Secretion in Macrophages Infected with Listeria monocytogenes

(2010) S. R. Dewamitta et al.   INFECTION AND IMMUNITY

Blocking IL-1α but not IL-1β increases susceptibility to chronic Mycobacterium tuberculosis infection in mice

(2010) Reto Guler et al.   VACCINE

The RD1 Locus in the Mycobacterium tuberculosis Genome Contributes to Activation of Caspase-1 via Induction of Potassium Ion Efflux in Infected Macrophages

(2009) T. Kurenuma et al.   INFECTION AND IMMUNITY

Mycobacterial infection induces the secretion of high-mobility group box 1 protein

(2008) Ajay Grover et al.   CELLULAR MICROBIOLOGY

Calcium Signaling in Dendritic Cells by Human or Mycobacterial Hsp70 Is Caused by Contamination and Is Not Required for Hsp70-mediated Enhancement of Cross-presentation

(2008) Henriette Bendz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Dynamics and Mechanisms of Interleukin-1α and β Nuclear Import

(2008) Nadia M. Luheshi et al.   TRAFFIC