Epigenetic regulation for acquiring glial identity by neural stem cells during cortical development

Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion

(2019) Taito Matsuda et al.   NEURON

FGF Signaling Directs the Cell Fate Switch from Neurons to Astrocytes in the Developing Mouse Cerebral Cortex

(2019) Tung Anh Dinh Duong et al.   JOURNAL OF NEUROSCIENCE

Plag1 regulates neuronal gene expression and neuronal differentiation of neocortical neural progenitor cells

(2019) Hiroshi Sakai et al.   GENES TO CELLS

Temporal plasticity of apical progenitors in the developing mouse neocortex

(2019) Polina Oberst et al.   NATURE

Diverse gene regulatory mechanisms mediated by Polycomb group proteins during neural development

(2019) Masafumi Tsuboi et al.   CURRENT OPINION IN NEUROBIOLOGY

Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus

(2018) Sofia A. Quinodoz et al.   CELL

Epigenetics and epitranscriptomics in temporal patterning of cortical neural progenitor competence

(2018) Ki-Jun Yoon et al.   JOURNAL OF CELL BIOLOGY

Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion

(2018) Yubin Huang et al.   NATURE NEUROSCIENCE

Layer-specific morphological and molecular differences in neocortical astrocytes and their dependence on neuronal layers

(2018) Darin Lanjakornsiripan et al.   Nature Communications

Epigenetic and Transcriptional Pre-patterning—An Emerging Theme in Cortical Neurogenesis

(2018) Mareike Albert et al.   Frontiers in Neuroscience

Ubiquitination-Independent Repression of PRC1 Targets during Neuronal Fate Restriction in the Developing Mouse Neocortex

(2018) Masafumi Tsuboi et al.   DEVELOPMENTAL CELL

Neuronal specification in space and time

(2018) Isabel Holguera et al.   SCIENCE

Microglia and early brain development: An intimate journey

(2018) Morgane S. Thion et al.   SCIENCE

Regulation of Chromatin Structure During Neural Development

(2018) Yusuke Kishi et al.   Frontiers in Neuroscience

Complex multi-enhancer contacts captured by genome architecture mapping

(2017) Robert A. Beagrie et al.   NATURE

3D structures of individual mammalian genomes studied by single-cell Hi-C

(2017) Tim J. Stevens et al.   NATURE

Identification of diverse astrocyte populations and their malignant analogs

(2017) Chia-Ching John Lin et al.   NATURE NEUROSCIENCE

HMGN1 and 2 remodel core and linker histone tail domains within chromatin

(2017) Kevin J. Murphy et al.   NUCLEIC ACIDS RESEARCH

DNA Methylome Analysis Identifies Transcription Factor-Based Epigenomic Signatures of Multilineage Competence in Neural Stem/Progenitor Cells

(2017) Tsukasa Sanosaka et al.   Cell Reports

Layer-specific chromatin accessibility landscapes reveal regulatory networks in adult mouse visual cortex

(2017) Lucas T Gray et al.   eLife

Imaging Specific Genomic DNA in Living Cells

(2016) Baohui Chen et al.   Annual Review of Biophysics

Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming

(2016) Sergio Gascón et al.   Cell Stem Cell

Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

(2016) M Ryan Corces et al.   NATURE GENETICS

Editing the epigenome: technologies for programmable transcription and epigenetic modulation

(2016) Pratiksha I Thakore et al.   NATURE METHODS

Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells

(2016) Yuanchao Xue et al.   NATURE NEUROSCIENCE

Regulation of Genome Architecture and Function by Polycomb Proteins

(2016) Marianne Entrevan et al.   TRENDS IN CELL BIOLOGY

Epigenome Editing: State of the Art, Concepts, and Perspectives

(2016) Goran Kungulovski et al.   TRENDS IN GENETICS

Zbtb20 promotes astrocytogenesis during neocortical development

(2016) Motoshi Nagao et al.   Nature Communications

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Transcriptional Mechanisms of Proneural Factors and REST in Regulating Neuronal Reprogramming of Astrocytes

(2015) Giacomo Masserdotti et al.   Cell Stem Cell

NeuroD1 reprograms chromatin and transcription factor landscapes to induce the neuronal program

(2015) A. Pataskar et al.   EMBO JOURNAL

Single-cell chromatin accessibility reveals principles of regulatory variation

(2015) Jason D. Buenrostro et al.   NATURE

Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state

(2015) Assaf Rotem et al.   NATURE BIOTECHNOLOGY

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

(2015) A. Zeisel et al.   SCIENCE

Rapid and Efficient Direct Conversion of Human Adult Somatic Cells into Neural Stem Cells by HMGA2/let-7b

(2015) Kyung-Rok Yu et al.   Cell Reports

Ngn1 inhibits astrogliogenesis through induction of miR-9 during neuronal fate specification

(2015) Jing Zhao et al.   eLife

MicroRNA-153 Regulates the Acquisition of Gliogenic Competence by Neural Stem Cells

(2015) Jun Tsuyama et al.   Stem Cell Reports

Dynamic expression and roles of Hes factors in neural development

(2014) Ryoichiro Kageyama et al.   CELL AND TISSUE RESEARCH

Neurogenesis during development of the vertebrate central nervous system

(2014) J. T. Paridaen et al.   EMBO REPORTS

MicroRNA miR-124 Controls the Choice between Neuronal and Astrocyte Differentiation by Fine-tuning Ezh2 Expression

(2014) Wen Hao Neo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single-cell RNA-seq reveals dynamic paracrine control of cellular variation

(2014) Alex K. Shalek et al.   NATURE

Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subtypes

(2014) Stacey M Glasgow et al.   NATURE NEUROSCIENCE

The miR-17/106-p38 axis is a key regulator of the neurogenic-to-gliogenic transition in developing neural stem/progenitor cells

(2014) H. Naka-Kaneda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High Mobility Group Nucleosome-Binding Family Proteins Promote Astrocyte Differentiation of Neural Precursor Cells

(2014) Motoshi Nagao et al.   STEM CELLS

MicroRNAs in brain development and function: a matter of flexibility and stability

(2014) Philipp Follert et al.   Frontiers in Molecular Neuroscience

Direct Conversion of Fibroblasts to Neurons by Reprogramming PTB-Regulated MicroRNA Circuits

(2013) Yuanchao Xue et al.   CELL

Single-Cell Dynamics of Genome-Nuclear Lamina Interactions

(2013) Jop Kind et al.   CELL

The BAF Complex Interacts with Pax6 in Adult Neural Progenitors to Establish a Neurogenic Cross-Regulatory Transcriptional Network

(2013) Jovica Ninkovic et al.   Cell Stem Cell

In Vivo Direct Reprogramming of Reactive Glial Cells into Functional Neurons after Brain Injury and in an Alzheimer’s Disease Model

(2013) Ziyuan Guo et al.   Cell Stem Cell

The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation

(2013) Anke Sparmann et al.   EMBO JOURNAL

Epigenomic enhancer annotation reveals a key role for NFIX in neural stem cell quiescence

(2013) B. Martynoga et al.   GENES & DEVELOPMENT

IMP2 regulates differentiation potentials of mouse neocortical neural precursor cells

(2013) Yuki Fujii et al.   GENES TO CELLS

Single-cell Hi-C reveals cell-to-cell variability in chromosome structure

(2013) Takashi Nagano et al.   NATURE

Transcriptional regulation by Polycomb group proteins

(2013) Luciano Di Croce et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development

(2012) S.-L. Tan et al.   DEVELOPMENT

HMGA regulates the global chromatin state and neurogenic potential in neocortical precursor cells

(2012) Yusuke Kishi et al.   NATURE NEUROSCIENCE

Sox9 and NFIA Coordinate a Transcriptional Regulatory Cascade during the Initiation of Gliogenesis

(2012) Peng Kang et al.   NEURON

HMGA1 Reprograms Somatic Cells into Pluripotent Stem Cells by Inducing Stem Cell Transcriptional Networks

(2012) Sandeep N. Shah et al.   PLoS One

Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity

(2012) Mitsuhiro Endoh et al.   PLoS Genetics

Compaction of chromatin by diverse Polycomb group proteins requires localized regions of high charge

(2011) D. J. Grau et al.   GENES & DEVELOPMENT

Wnt Signaling Regulates Neuronal Differentiation of Cortical Intermediate Progenitors

(2011) R. N. Munji et al.   JOURNAL OF NEUROSCIENCE

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

ESCs Require PRC2 to Direct the Successful Reprogramming of Differentiated Cells toward Pluripotency

(2010) Carlos F. Pereira et al.   Cell Stem Cell

Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex

(2010) A. Kuwahara et al.   DEVELOPMENT

BMP-induced REST regulates the establishment and maintenance of astrocytic identity

(2010) Jun Kohyama et al.   JOURNAL OF CELL BIOLOGY

Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons

(2010) Jian Feng et al.   NATURE NEUROSCIENCE

Epigenetic control of neural precursor cell fate during development

(2010) Yusuke Hirabayashi et al.   NATURE REVIEWS NEUROSCIENCE

Directing Astroglia from the Cerebral Cortex into Subtype Specific Functional Neurons

(2010) Christophe Heinrich et al.   PLOS BIOLOGY

Regulation of chromatin structure and function By HMGN proteins

(2009) Yuri Postnikov et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Committed Neuronal Precursors Confer Astrocytic Potential on Residual Neural Precursor Cells

(2009) Masakazu Namihira et al.   DEVELOPMENTAL CELL

Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain

(2009) C. A. Fasano et al.   GENES & DEVELOPMENT

Chd1 regulates open chromatin and pluripotency of embryonic stem cells

(2009) Alexandre Gaspar-Maia et al.   NATURE

Polycomb Limits the Neurogenic Competence of Neural Precursor Cells to Promote Astrogenic Fate Transition

(2009) Yusuke Hirabayashi et al.   NEURON

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

Hmga2 Promotes Neural Stem Cell Self-Renewal in Young but Not Old Mice by Reducing p16Ink4a and p19Arf Expression

(2008) Jinsuke Nishino et al.   CELL

Cleavage of the Wnt Receptor Ryk Regulates Neuronal Differentiation during Cortical Neurogenesis

(2008) Jungmook Lyu et al.   DEVELOPMENTAL CELL

REST maintains self-renewal and pluripotency of embryonic stem cells

(2008) Sanjay K. Singh et al.   NATURE

Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development

(2008) Hayato Naka et al.   NATURE NEUROSCIENCE