Influence of Sae-regulated and Agr-regulated factors on the escape ofStaphylococcus aureusfrom human macrophages

Inability to sustain intraphagolysosomal killing ofStaphylococcus aureuspredisposes to bacterial persistence in macrophages

(2015) Jamil Jubrail et al.   CELLULAR MICROBIOLOGY

Intracellular replication ofStaphylococcus aureusin mature phagolysosomes in macrophages precedes host cell death, and bacterial escape and dissemination

(2015) Ronald S. Flannagan et al.   CELLULAR MICROBIOLOGY

Staphylococcus aureus Strain USA300 Perturbs Acquisition of Lysosomal Enzymes and Requires Phagosomal Acidification for Survival inside Macrophages

(2015) Zachary R. Tranchemontagne et al.   INFECTION AND IMMUNITY

Novel antibody–antibiotic conjugate eliminates intracellular S. aureus

(2015) Sophie M. Lehar et al.   NATURE

Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia

(2015) Norberto González-Juarbe et al.   PLoS Pathogens

Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular

(2015) Jason H. Melehani et al.   PLoS Pathogens

Toxin-Induced Necroptosis Is a Major Mechanism of Staphylococcus aureus Lung Damage

(2015) Kipyegon Kitur et al.   PLoS Pathogens

Thepsmα Locus Regulates Production of Staphylococcus aureus Alpha-Toxin during Infection

(2014) Bryan J. Berube et al.   INFECTION AND IMMUNITY

The Bicomponent Pore-Forming Leucocidins of Staphylococcus aureus

(2014) Francis Alonzo et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

A Nasal Epithelial Receptor for Staphylococcus aureus WTA Governs Adhesion to Epithelial Cells and Modulates Nasal Colonization

(2014) Stefanie Baur et al.   PLoS Pathogens

Neutrophils Versus Staphylococcus aureus: A Biological Tug of War

(2013) András N. Spaan et al.   Annual Review of Microbiology

Staphylococcal alpha-phenol soluble modulins contribute to neutrophil lysis after phagocytosis

(2013) B. G. J. Surewaard et al.   CELLULAR MICROBIOLOGY

Staphylococcus aureus Elaborates Leukocidin AB To Mediate Escape from within Human Neutrophils

(2013) Ashley L. DuMont et al.   INFECTION AND IMMUNITY

Identification of a Crucial Residue Required for Staphylococcus aureus LukAB Cytotoxicity and Receptor Recognition

(2013) Ashley L. DuMont et al.   INFECTION AND IMMUNITY

The Role of Innate Immunity in Promoting SaeR/S-Mediated Virulence in Staphylococcus aureus

(2013) Oliwia W. Zurek et al.   Journal of Innate Immunity

Phenol-soluble modulins and staphylococcal infection

(2013) Andreas Peschel et al.   NATURE REVIEWS MICROBIOLOGY

Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin Mac-1

(2013) A. L. DuMont et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Soluble CD163 promotes recognition, phagocytosis and killing of Staphylococcus aureus via binding of specific fibronectin peptides

(2012) Jessica Kneidl et al.   CELLULAR MICROBIOLOGY

MRSA virulence and spread

(2012) Michael Otto   CELLULAR MICROBIOLOGY

Organizational Requirements of the SaeR Binding Sites for a Functional P1 Promoter of the sae Operon in Staphylococcus aureus

(2012) H. Cho et al.   JOURNAL OF BACTERIOLOGY

Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome

(2012) Dirk Holzinger et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Staphylococcus aureus determinants for nasal colonization

(2012) Christopher Weidenmaier et al.   TRENDS IN MICROBIOLOGY

CcpA Regulates Arginine Biosynthesis in Staphylococcus aureus through Repression of Proline Catabolism

(2012) Austin S. Nuxoll et al.   PLoS Pathogens

The Stringent Response of Staphylococcus aureus and Its Impact on Survival after Phagocytosis through the Induction of Intracellular PSMs Expression

(2012) Tobias Geiger et al.   PLoS Pathogens

Intracellular staphylococcus aureus: Live-in and let die

(2012) Martin Fraunholz et al.   Frontiers in Cellular and Infection Microbiology

Neutrophils in innate host defense against Staphylococcus aureus infections

(2011) Kevin M. Rigby et al.   Seminars in Immunopathology

Expression of δ-toxin by Staphylococcus aureus mediates escape from phago-endosomes of human epithelial and endothelial cells in the presence of β-toxin

(2010) Bernd Giese et al.   CELLULAR MICROBIOLOGY

Identification of a Novel Staphylococcus aureus Two-Component Leukotoxin Using Cell Surface Proteomics

(2010) Christy L. Ventura et al.   PLoS One

Staphylococcus aureus Panton-Valentine Leukocidin Is a Very Potent Cytotoxic Factor for Human Neutrophils

(2010) Bettina Löffler et al.   PLoS Pathogens

SaeR Binds a Consensus Sequence within Virulence Gene Promoters to Advance USA300 Pathogenesis

(2009) Tyler K. Nygaard et al.   JOURNAL OF INFECTIOUS DISEASES

Transcription of the phage-encoded Panton-Valentine leukocidin of Staphylococcus aureus is dependent on the phage life-cycle and on the host background

(2009) C. Wirtz et al.   MICROBIOLOGY-SGM

Phagocytosis of Staphylococcus aureus by Macrophages Exerts Cytoprotective Effects Manifested by the Upregulation of Antiapoptotic Factors

(2009) Joanna Koziel et al.   PLoS One

The Virulence Regulator Sae of Staphylococcus aureus: Promoter Activities and Response to Phagocytosis-Related Signals

(2008) T. Geiger et al.   JOURNAL OF BACTERIOLOGY

RNAIII-Independent Target Gene Control by the agr Quorum-Sensing System: Insight into the Evolution of Virulence Regulation in Staphylococcus aureus

(2008) Shu Y. Queck et al.   MOLECULAR CELL

A Potential New Pathway for Staphylococcus aureus Dissemination: The Silent Survival of S. aureus Phagocytosed by Human Monocyte-Derived Macrophages

(2008) Malgorzata Kubica et al.   PLoS One