Tetramethylpyrazine Protects Against Oxygen-Glucose Deprivation-Induced Brain Microvascular Endothelial Cells Injury via Rho/Rho-kinase Signaling Pathway

Tetramethylpyrazine inhibits neutrophil activation following permanent cerebral ischemia in rats

(2015) Cheng-Yi Chang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of Rho/Rho-kinase pathway and the neuroprotective effects of fasudil in chronic cerebral ischemia

(2015) Yan-kun Shao et al.   Neural Regeneration Research

In vitro model of the blood-brain barrier established by co-culture of primary cerebral microvascular endothelial and astrocyte cells

(2015) Ning Wang et al.   Neural Regeneration Research

Inhibition of Rho-kinase protects cerebral barrier from ischaemia-evoked injury through modulations of endothelial cell oxidative stress and tight junctions

(2014) Claire L. Gibson et al.   JOURNAL OF NEUROCHEMISTRY

Ultrasound-Enhanced Protective Effect of Tetramethylpyrazine against Cerebral Ischemia/Reperfusion Injury

(2014) Chunbing Zhang et al.   PLoS One

Curcumin inhibits AP-2γ-induced apoptosis in the human malignant testicular germ cells in vitro

(2013) Chang Zhou et al.   ACTA PHARMACOLOGICA SINICA

Tetramethylpyrazine reduces cellular inflammatory response following permanent focal cerebral ischemia in rats

(2013) Tsung-Kuei Kao et al.   EXPERIMENTAL NEUROLOGY

Neuroproteomics approach and neurosystems biology analysis: ROCK inhibitors as promising therapeutic targets in neurodegeneration and neurotrauma

(2012) Mohamad Raad et al.   ELECTROPHORESIS

Activation of AMP-activated protein kinase alleviates High-glucose-induced dysfunction of brain microvascular endothelial cell tight-junction dynamics

(2012) Chao Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hypoxia-reoxygenation-induced endothelial barrier failure: role of RhoA, Rac1 and myosin light chain kinase

(2012) Muhammad Aslam et al.   JOURNAL OF PHYSIOLOGY-LONDON

Agmatine promotes the migration of murine brain endothelial cells via multiple signaling pathways

(2012) Hyun-Joo Jung et al.   LIFE SCIENCES

Involvement of oxidative stress in hypoxia-induced blood–brain barrier breakdown

(2012) Abraham Al Ahmad et al.   MICROVASCULAR RESEARCH

Involvement of microglial RhoA/Rho-Kinase pathway activation in the dopaminergic neuron death. Role of angiotensin via angiotensin type 1 receptors

(2012) Begoña Villar-Cheda et al.   NEUROBIOLOGY OF DISEASE

Geniposide Reduces Inflammatory Responses of Oxygen-Glucose Deprived Rat Microglial Cells via Inhibition of the TLR4 Signaling Pathway

(2012) Jun Wang et al.   NEUROCHEMICAL RESEARCH

Inhibition of Rho kinase by hydroxyfasudil attenuates brain edema after subarachnoid hemorrhage in rats

(2012) Mutsumi Fujii et al.   NEUROCHEMISTRY INTERNATIONAL

Targeted modulation of reactive oxygen species in the vascular endothelium

(2011) Vladimir V. Shuvaev et al.   JOURNAL OF CONTROLLED RELEASE

Catalase and Superoxide Dismutase Conjugated with Platelet-Endothelial Cell Adhesion Molecule Antibody Distinctly Alleviate Abnormal Endothelial Permeability Caused by Exogenous Reactive Oxygen Species and Vascular Endothelial Growth Factor

(2011) J. Han et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Fasudil and Ozagrel in Combination Show Neuroprotective Effects on Cerebral Infarction after Murine Middle Cerebral Artery Occlusion

(2011) A. Koumura et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Reactive oxygen species and ischemic cerebrovascular disease

(2011) Inan Olmez et al.   NEUROCHEMISTRY INTERNATIONAL

Looking at the blood–brain barrier: Molecular anatomy and possible investigation approaches

(2010) Filipa Lourenço Cardoso et al.   BRAIN RESEARCH REVIEWS

The NO cascade, eNOS location, and microvascular permeability

(2010) W. N. Duran et al.   CARDIOVASCULAR RESEARCH

Oxidative Stress Increases Blood–Brain Barrier Permeability and Induces Alterations in Occludin during Hypoxia–Reoxygenation

(2010) Jeffrey J Lochhead et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Role of Rho kinase in sphingosine 1-phosphate-mediated endothelial and smooth muscle cell migration and differentiation

(2010) Kevin A. Harvey et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Brain Endothelial Cell Death: Modes, Signaling Pathways, and Relevance to Neural Development, Homeostasis, and Disease

(2010) Maria Teresa Rizzo et al.   MOLECULAR NEUROBIOLOGY

Neuroprotection and enhanced neurogenesis by tetramethylpyrazine in adult rat brain after focal ischemia

(2010) Xinli Xiao et al.   NEUROLOGICAL RESEARCH

Role of Rac1 GTPase in NADPH Oxidase Activation and Cognitive Impairment Following Cerebral Ischemia in the Rat

(2010) Limor Raz et al.   PLoS One

Small GTPase RhoA and Its Effector Rho Kinase Mediate Oxygen Glucose Deprivation-Evoked In Vitro Cerebral Barrier Dysfunction

(2010) Claire Allen et al.   STROKE

Closing the gap between the in-vivo and in-vitro blood–brain barrier tightness

(2009) Katayun Cohen-Kashi Malina et al.   BRAIN RESEARCH

Targeting eNOS and beyond: emerging heterogeneity of the role of endothelial Rho proteins in stroke protection

(2009) Naoki Sawada et al.   Expert Review of Neurotherapeutics

Involvement of ROS in BBB dysfunction

(2009) Pamela B. L. Pun et al.   FREE RADICAL RESEARCH

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Rac1 Is a Critical Mediator of Endothelium-Derived Neurotrophic Activity

(2009) N. Sawada et al.   Science Signaling

Antiepileptic effects of two Rho-kinase inhibitors, Y-27632 and fasudil, in mice

(2008) S Y İnan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Blood Brain Barrier in Hypoxic-Ischemic Conditions

(2008) C. Kaur et al.   CURRENT NEUROVASCULAR RESEARCH

Mechanisms of ischemic brain damage

(2008) Kristian P. Doyle et al.   NEUROPHARMACOLOGY