Inhibition of Rho-kinase protects cerebral barrier from ischaemia-evoked injury through modulations of endothelial cell oxidative stress and tight junctions

Hyperglycaemia promotes cerebral barrier dysfunction through activation of protein kinase C-β

(2013) B. Shao et al.   DIABETES OBESITY & METABOLISM

Modifying expression of EphA4 and its downstream targets improves functional recovery after stroke

(2013) Robin Lemmens et al.   HUMAN MOLECULAR GENETICS

PKC-β Exacerbates in vitro Brain Barrier Damage in Hyperglycemic Settings via Regulation of RhoA/Rho-kinase/MLC2 Pathway

(2013) Kirtiman Srivastava et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroprotection for Ischaemic Stroke: Translation from the Bench to the Bedside

(2012) Brad A. Sutherland et al.   International Journal of Stroke

Inhibition of Rho kinase by hydroxyfasudil attenuates brain edema after subarachnoid hemorrhage in rats

(2012) Mutsumi Fujii et al.   NEUROCHEMISTRY INTERNATIONAL

A Rho kinase (ROCK) inhibitor, fasudil, prevents matrix metalloproteinase-9-related hemorrhagic transformation in mice treated with tissue plasminogen activator

(2012) M. Ishiguro et al.   NEUROSCIENCE

Progesterone is neuroprotective following cerebral ischaemia in reproductively ageing female mice

(2011) C. L. Gibson et al.   BRAIN

Role of Rho Kinase in Microvascular Damage Following Cerebral Ischemia Reperfusion in Rats

(2011) Kang Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of RhoA/ROCK Signaling in Endothelial-Monocyte-Activating Polypeptide II Opening of the Blood–Tumor Barrier

(2011) Hui Xie et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Evidence for involvement of ROCK signaling in bradykinin-induced increase in murine blood–tumor barrier permeability

(2011) Teng Ma et al.   JOURNAL OF NEURO-ONCOLOGY

Modulation of NADPH oxidase activation in cerebral ischemia/reperfusion injury in rats

(2010) Tiziana Genovese et al.   BRAIN RESEARCH

Fasudil Mesylate Protects PC12 Cells from Oxidative Stress Injury via the Bax-Mediated Pathway

(2010) Qin Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Protein Kinase C Activation Modulates Reversible Increase in Cortical Blood–Brain Barrier Permeability and Tight Junction Protein Expression during Hypoxia and Posthypoxic Reoxygenation

(2010) Colin L Willis et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Fasudil protects hippocampal neurons against hypoxia-reoxygenation injury by suppressing microglial inflammatory responses in mice

(2010) Jing Ding et al.   JOURNAL OF NEUROCHEMISTRY

Small GTPase RhoA and Its Effector Rho Kinase Mediate Oxygen Glucose Deprivation-Evoked In Vitro Cerebral Barrier Dysfunction

(2010) Claire Allen et al.   STROKE

Antioxidants attenuate hyperglycaemia-mediated brain endothelial cell dysfunction and blood-brain barrier hyperpermeability

(2009) C. L. Allen et al.   DIABETES OBESITY & METABOLISM

Oxidative Stress and Its Role in the Pathogenesis of Ischaemic Stroke

(2009) C. L. Allen et al.   International Journal of Stroke

Fasudil, a Rho kinase inhibitor, drives mobilization of adult neural stem cells after hypoxia/reoxygenation injury in mice

(2009) Jing Ding et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Phosphorylation of Claudin-5 and Occludin by Rho Kinase in Brain Endothelial Cells

(2008) Masaru Yamamoto et al.   AMERICAN JOURNAL OF PATHOLOGY

Neuroprotective Potential of Fasudil Mesylate in Brain Ischemia-Reperfusion Injury of Rats

(2008) Qin Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Demonstration of elevation and localization of Rho-kinase activity in the brain of a rat model of cerebral infarction

(2008) Kazuo Yano et al.   EUROPEAN JOURNAL OF PHARMACOLOGY