Metformin Attenuates Cognitive Impairments in Hypoxia–Ischemia Neonatal Rats via Improving Remyelination

H2S attenuates cognitive deficits through Akt1/JNK3 signaling pathway in ischemic stroke

(2014) Xiangru Wen et al.   BEHAVIOURAL BRAIN RESEARCH

Quercetin improves hypoxia-ischemia induced cognitive deficits via promoting remyelination in neonatal rat

(2014) Xuebin Qu et al.   BRAIN RESEARCH

Chronic metformin treatment improves post-stroke angiogenesis and recovery after experimental stroke

(2014) Venugopal R. Venna et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Pre-treatment with metformin activates Nrf2 antioxidant pathways and inhibits inflammatory responses through induction of AMPK after transient global cerebral ischemia

(2014) Ghorbangol Ashabi et al.   METABOLIC BRAIN DISEASE

Revisiting the mechanisms of metformin action in the liver

(2013) Benoit Viollet et al.   ANNALES D ENDOCRINOLOGIE

Metformin Increases Mitochondrial Energy Formation in L6 Muscle Cell Cultures

(2013) Veeravenkata S. Vytla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two Weeks of Metformin Treatment Enhances Mitochondrial Respiration in Skeletal Muscle of AMPK Kinase Dead but Not Wild Type Mice

(2013) Jonas M. Kristensen et al.   PLoS One

Long-Term Post-Stroke Changes Include Myelin Loss, Specific Deficits in Sensory and Motor Behaviors and Complex Cognitive Impairment Detected Using Active Place Avoidance

(2013) Jin Zhou et al.   PLoS One

Metformin: an old but still the best treatment for type 2 diabetes

(2013) Lilian Beatriz Aguayo Rojas et al.   Diabetology & Metabolic Syndrome

Periventricular leukomalacia long-term prognosis may be improved by treatment with UDP-glucose, GDNF, and memantine in neonatal rats

(2012) Feng-xia Mao et al.   BRAIN RESEARCH

Metformin Activates an Atypical PKC-CBP Pathway to Promote Neurogenesis and Enhance Spatial Memory Formation

(2012) Jing Wang et al.   Cell Stem Cell

Olig2-dependent developmental fate switch of NG2 cells

(2012) X. Zhu et al.   DEVELOPMENT

Ibuprofen inhibits neuroinflammation and attenuates white matter damage following hypoxia–ischemia in the immature rodent brain

(2011) M.L. Carty et al.   BRAIN RESEARCH

Chronic Neurological Deficits in Mice after Perinatal Hypoxia and Ischemia Correlate with Hemispheric Tissue Loss and White Matter Injury Detected by MRI

(2011) Pelin Cengiz et al.   DEVELOPMENTAL NEUROSCIENCE

Reduced White Matter Integrity Is Related to Cognitive Instability

(2011) A. M. Fjell et al.   JOURNAL OF NEUROSCIENCE

Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination

(2011) Stephen P J Fancy et al.   NATURE NEUROSCIENCE

Aerobic exercise prevents age-dependent cognitive decline and reduces anxiety-related behaviors in middle-aged and old rats

(2011) A. Pietrelli et al.   NEUROSCIENCE

Towards resolving the transcription factor network controlling myelin gene expression

(2011) Debra L. Fulton et al.   NUCLEIC ACIDS RESEARCH

Abnormal corpus callosum in neonates after hypoxic-ischemic injury

(2011) Monica Epelman et al.   PEDIATRIC RADIOLOGY

A Role for Hemopexin in Oligodendrocyte Differentiation and Myelin Formation

(2011) Noemi Morello et al.   PLoS One

Intermittent Hypoxia after Transient Focal Ischemia Induces Hippocampal Neurogenesis and c-Fos Expression and Reverses Spatial Memory Deficits in Rats

(2011) Yi-Wei Tsai et al.   PLoS One

Differential Susceptibility to Axonopathy in Necrotic and Non-Necrotic Perinatal White Matter Injury

(2011) Art Riddle et al.   STROKE

Ex Vivo Diffusion Tensor Imaging and Neuropathological Correlation in a Murine Model of Hypoxia–Ischemia-Induced Thrombotic Stroke

(2010) Ahmed Shereen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Tyrosine phosphatases Shp1 and Shp2 have unique and opposing roles in oligodendrocyte development

(2010) Emory Kuo et al.   JOURNAL OF NEUROCHEMISTRY

Oligovascular Signaling in White Matter Stroke

(2009) Ken Arai et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Long-term cognitive impairment and myelination deficiency in a rat model of perinatal hypoxic-ischemic brain injury

(2009) Zhiheng Huang et al.   BRAIN RESEARCH

Selective Losses of Brainstem Catecholamine Neurons After Hypoxia-Ischemia in the Immature Rat Pup

(2009) Kathryn M Buller et al.   PEDIATRIC RESEARCH

Assessing the Severity of Perinatal Hypoxia-Ischemia in Piglets Using Near-Infrared Spectroscopy to Measure the Cerebral Metabolic Rate of Oxygen

(2009) Kenneth M Tichauer et al.   PEDIATRIC RESEARCH

NMDA Receptor Blockade with Memantine Attenuates White Matter Injury in a Rat Model of Periventricular Leukomalacia

(2008) S. M. Manning et al.   JOURNAL OF NEUROSCIENCE