Aminochrome induces dopaminergic neuronal dysfunction: a new animal model for Parkinson’s disease

The need of a new and more physiological preclinical model for Parkinson’s disease

(2016) Juan Segura-Aguilar et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Aminochrome as New Preclinical Model to Find New Pharmacological Treatment that Stop the Development of Parkinson’s Disease

(2016) Juan Segura-Aguilar et al.   CURRENT MEDICINAL CHEMISTRY

Characterization of a new low-dose 6-hydroxydopamine model of Parkinson's disease in rat

(2016) Anna-Maija Penttinen et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Direct intranigral injection of dopaminochrome causes degeneration of dopamine neurons

(2016) Jillienne C. Touchette et al.   NEUROSCIENCE LETTERS

Current disease modifying approaches to treat Parkinson’s disease

(2015) Dan Lindholm et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Trophic factors for Parkinson's disease: To live or let die

(2015) C. Warren Olanow et al.   MOVEMENT DISORDERS

Balancing the basal ganglia circuitry: A possible new role for dopamine D2 receptors in health and disease

(2015) Maxime Cazorla et al.   MOVEMENT DISORDERS

A new mechanism for protection of dopaminergic neurons mediated by astrocytes

(2015) Juan Segura-Aguilar   Neural Regeneration Research

Aminochrome Toxicity is Mediated by Inhibition of Microtubules Polymerization Through the Formation of Adducts with Tubulin

(2015) Andrea Briceño et al.   NEUROTOXICITY RESEARCH

Neurotoxin Mechanisms and Processes Relevant to Parkinson’s Disease: An Update

(2015) Juan Segura-Aguilar et al.   NEUROTOXICITY RESEARCH

DT-Diaphorase Prevents Aminochrome-Induced Alpha-Synuclein Oligomer Formation and Neurotoxicity

(2015) Patricia Muñoz et al.   TOXICOLOGICAL SCIENCES

Functional mitochondrial analysis in acute brain sections from adult rats reveals mitochondrial dysfunction in a rat model of migraine

(2014) Nathan T. Fried et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Glutathione transferase mu 2 protects glioblastoma cells against aminochrome toxicity by preventing autophagy and lysosome dysfunction

(2014) Sandro Huenchuguala et al.   Autophagy

Protective and toxic roles of dopamine in Parkinson's disease

(2014) Juan Segura-Aguilar et al.   JOURNAL OF NEUROCHEMISTRY

Glutathione Transferase-M2-2 Secreted from Glioblastoma Cell Protects SH-SY5Y Cells from Aminochrome Neurotoxicity

(2014) Carlos Cuevas et al.   NEUROTOXICITY RESEARCH

Quinone-induced protein handling changes: Implications for major protein handling systems in quinone-mediated toxicity

(2014) Rui Xiong et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

α-Synuclein and Mitochondrial Dysfunction in Parkinson’s Disease

(2013) Stephen Mullin et al.   MOLECULAR NEUROBIOLOGY

An ERcentric view of Parkinson's disease

(2013) Gabriela Mercado et al.   TRENDS IN MOLECULAR MEDICINE

Protein degradation pathways in Parkinson’s disease: curse or blessing

(2012) Darius Ebrahimi-Fakhari et al.   ACTA NEUROPATHOLOGICA

α-Synuclein oligomers and clinical implications for Parkinson disease

(2012) Lorraine V. Kalia et al.   ANNALS OF NEUROLOGY

Overexpression of VMAT-2 and DT-diaphorase protects substantia nigra-derived cells against aminochrome neurotoxicity

(2012) Patricia Muñoz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The dopamine metabolite aminochrome inhibits mitochondrial complex I and modifies the expression of iron transporters DMT1 and FPN1

(2012) Pabla Aguirre et al.   BIOMETALS

Dopamine Oxidation and Autophagy

(2012) Patricia Muñoz et al.   Parkinsons Disease

Animal models of Parkinson's disease: a source of novel treatments and clues to the cause of the disease

(2011) Susan Duty et al.   BRITISH JOURNAL OF PHARMACOLOGY

Autophagy Protects Against Aminochrome-Induced Cell Death in Substantia Nigra-Derived Cell Line

(2011) Irmgard Paris et al.   TOXICOLOGICAL SCIENCES

Stable Expression of Short Interfering RNA for DT-Diaphorase Induces Neurotoxicity

(2010) Jorge Lozano et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Aminochrome Induces Disruption of Actin, Alpha-, and Beta-Tubulin Cytoskeleton Networks in Substantia-Nigra-Derived Cell Line

(2010) Irmgard Paris et al.   NEUROTOXICITY RESEARCH

The rotational model and microdialysis: Significance for dopamine signalling, clinical studies, and beyond

(2009) Mario Herrera-Marschitz et al.   PROGRESS IN NEUROBIOLOGY