DT-Diaphorase Prevents Aminochrome-Induced Alpha-Synuclein Oligomer Formation and Neurotoxicity

Glutathione transferase mu 2 protects glioblastoma cells against aminochrome toxicity by preventing autophagy and lysosome dysfunction

(2014) Sandro Huenchuguala et al.   Autophagy

Intranasal administration of alpha-synuclein aggregates: a Parkinson's disease model with behavioral and neurochemical correlates

(2014) Marina A. Gruden et al.   BEHAVIOURAL BRAIN RESEARCH

Facile “stop codon” method reveals elevated neuronal toxicity by discrete S87p-α-synuclein oligomers

(2014) Yonghwang Ha et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Linking alpha-synuclein properties with oxidation: a hypothesis on a mechanism underling cellular aggregation

(2014) Suzanne Scarlata et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Protective and toxic roles of dopamine in Parkinson's disease

(2014) Juan Segura-Aguilar et al.   JOURNAL OF NEUROCHEMISTRY

Combination therapy in a transgenic model of Alzheimer's disease

(2013) Nurgul Aytan et al.   EXPERIMENTAL NEUROLOGY

Monogenic Parkinson's disease and parkinsonism: Clinical phenotypes and frequencies of known mutations

(2013) Andreas Puschmann   PARKINSONISM & RELATED DISORDERS

α-Synuclein Oligomers Induced by Docosahexaenoic Acid Affect Membrane Integrity

(2013) Chiara Fecchio et al.   PLoS One

Large  -synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking

(2013) B.-K. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The dopamine metabolite aminochrome inhibits mitochondrial complex I and modifies the expression of iron transporters DMT1 and FPN1

(2012) Pabla Aguirre et al.   BIOMETALS

Accumulation of Toxic  -Synuclein Oligomer within Endoplasmic Reticulum Occurs in  -Synucleinopathy In Vivo

(2012) E. Colla et al.   JOURNAL OF NEUROSCIENCE

Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy

(2012) Masatoshi Konno et al.   Molecular Neurodegeneration

Exosomal cell-to-cell transmission of alpha synuclein oligomers

(2012) Karin M Danzer et al.   Molecular Neurodegeneration

α-Synuclein oligomers oppose long-term potentiation and impair memory through a calcineurin-dependent mechanism: relevance to human synucleopathic diseases

(2011) Zane S. Martin et al.   JOURNAL OF NEUROCHEMISTRY

Amyloid formation and disaggregation of α-synuclein and its tandem repeat (α-TR)

(2010) Song Yi Bae et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular characterization of dopamine-derived quinones reactivity toward NADH and glutathione: Implications for mitochondrial dysfunction in Parkinson disease

(2010) Marco Bisaglia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Stable Expression of Short Interfering RNA for DT-Diaphorase Induces Neurotoxicity

(2010) Jorge Lozano et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Aminochrome Induces Disruption of Actin, Alpha-, and Beta-Tubulin Cytoskeleton Networks in Substantia-Nigra-Derived Cell Line

(2010) Irmgard Paris et al.   NEUROTOXICITY RESEARCH

Inducible over-expression of wild type α-synuclein in human neuronal cells leads to caspase-dependent non-apoptotic death

(2009) Kostas Vekrellis et al.   JOURNAL OF NEUROCHEMISTRY

Proteomic identification of dopamine-conjugated proteins from isolated rat brain mitochondria and SH-SY5Y cells

(2009) Victor S. Van Laar et al.   NEUROBIOLOGY OF DISEASE

The catecholaminergic RCSN-3 cell line: A model to study dopamine metabolism

(2009) Irmgard Paris et al.   NEUROTOXICITY RESEARCH

Molecular and Neurochemical Mechanisms in PD Pathogenesis

(2009) Irmgard Paris et al.   NEUROTOXICITY RESEARCH

Structural Characteristics of α-Synuclein Oligomers Stabilized by the Flavonoid Baicalein

(2008) Dong-Pyo Hong et al.   JOURNAL OF MOLECULAR BIOLOGY