Glutathione transferase mu 2 protects glioblastoma cells against aminochrome toxicity by preventing autophagy and lysosome dysfunction

Autophagy and microtubules - new story, old players

(2013) R. Mackeh et al.   JOURNAL OF CELL SCIENCE

Astrocyte-Specific Overexpression of Nrf2 Delays Motor Pathology and Synuclein Aggregation throughout the CNS in the Alpha-Synuclein Mutant (A53T) Mouse Model

(2012) L. Gan et al.   JOURNAL OF NEUROSCIENCE

Deficiency of ATP13A2 Leads to Lysosomal Dysfunction,  -Synuclein Accumulation, and Neurotoxicity

(2012) M. Usenovic et al.   JOURNAL OF NEUROSCIENCE

Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration

(2012) B. Dehay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimized Quantities of GDNF Overexpressed by Engineered Astrocytes Are Critical for Protection of Neuroblastoma Cells Against 6-OHDA Toxicity

(2011) Roya Safi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Synergy Between Glutathione Peroxidase-1 and Astrocytic Growth Factors Suppresses Free Radical Generation and Protects Dopaminergic Neurons against 6-Hydroxydopamine

(2011) Mossa Gardaneh et al.   REJUVENATION RESEARCH

Autophagy Protects Against Aminochrome-Induced Cell Death in Substantia Nigra-Derived Cell Line

(2011) Irmgard Paris et al.   TOXICOLOGICAL SCIENCES

Acetylated microtubules are required for fusion of autophagosomes with lysosomes

(2010) Rui Xie et al.   BMC CELL BIOLOGY

Physiological significance of selective degradation of p62 by autophagy

(2010) Masaaki Komatsu et al.   FEBS LETTERS

Aminochrome Induces Disruption of Actin, Alpha-, and Beta-Tubulin Cytoskeleton Networks in Substantia-Nigra-Derived Cell Line

(2010) Irmgard Paris et al.   NEUROTOXICITY RESEARCH

The cytosolic redox state of astrocytes: Maintenance, regulation and functional implications for metabolite trafficking

(2009) Johannes Hirrlinger et al.   BRAIN RESEARCH REVIEWS

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

(2009) C. Hetz et al.   GENES & DEVELOPMENT

Copper·Dopamine Complex Induces Mitochondrial Autophagy Preceding Caspase-independent Apoptotic Cell Death

(2009) Irmgard Paris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Proteomic identification of dopamine-conjugated proteins from isolated rat brain mitochondria and SH-SY5Y cells

(2009) Victor S. Van Laar et al.   NEUROBIOLOGY OF DISEASE

Critical role of lysosome and its associated protein cathepsin D in manganese-induced toxicity in cultured midbrain astrocyte

(2009) Xiaolan Fan et al.   NEUROCHEMISTRY INTERNATIONAL

Cathepsin D Is the Main Lysosomal Enzyme Involved in the Degradation of α-Synuclein and Generation of Its Carboxy-Terminally Truncated Species†

(2008) Daniel Sevlever et al.   BIOCHEMISTRY

Brain energetics (thought needs food)

(2008) Luc Pellerin   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Astrocyte and Neuron Intone Through Glutamate

(2008) Chun Zhang Yang et al.   NEUROCHEMICAL RESEARCH

The undertow of sulfur metabolism on glutamatergic neurotransmission

(2008) Ruma Banerjee et al.   TRENDS IN BIOCHEMICAL SCIENCES