Presentation of hepatocellular antigens

Hepatitis C Virus Infection Induces Autocrine Interferon Signaling by Human Liver Endothelial Cells and Release of Exosomes, Which Inhibits Viral Replication

(2015) Silvia Giugliano et al.   GASTROENTEROLOGY

Effective effector generation of CD8 + T cells and NK cells: A need for T-bet and ZEB-too

(2015) Sara E. Hamilton et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Kynurenine production mediated by indoleamine 2,3-dioxygenase aggravates liver injury in HBV-specific CTL-induced fulminant hepatitis

(2014) Hirofumi Ohtaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Effects of upregulated indoleamine 2, 3-dioxygenase 1 by interferon γ gene transfer on interferon γ-mediated antitumor activity

(2014) K Watcharanurak et al.   GENE THERAPY

Induction of hepatitis B virus surface antigen-specific cytotoxic T lymphocytes can be up-regulated by the inhibition of indoleamine 2, 3-dioxygenase activity

(2014) Hiroyasu Ito et al.   IMMUNOLOGY

APC licensing and CD4+T cell help in liver-stage malaria

(2014) Ian N. Crispe   Frontiers in Microbiology

Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation

(2013) Friederike Gieseke et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Microbiota-liver axis in hepatic disease

(2013) Benoit Chassaing et al.   HEPATOLOGY

Evolving therapies for liver fibrosis

(2013) Detlef Schuppan et al.   JOURNAL OF CLINICAL INVESTIGATION

Blockade of Chronic Type I Interferon Signaling to Control Persistent LCMV Infection

(2013) E. B. Wilson et al.   SCIENCE

Inflammation in Alcoholic Liver Disease

(2012) H. Joe Wang et al.   Annual Review of Nutrition

Short-Range Exosomal Transfer of Viral RNA from Infected Cells to Plasmacytoid Dendritic Cells Triggers Innate Immunity

(2012) Marlène Dreux et al.   Cell Host & Microbe

HCV-infected hepatocytes drive CD4+CD25+Foxp3+regulatory T-cell development through the Tim-3/Gal-9 pathway

(2012) Xiao J. Ji et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A High-Fat Diet Is Associated With Endotoxemia That Originates From the Gut

(2012) Swaroop Pendyala et al.   GASTROENTEROLOGY

Liver sinusoidal endothelial cells contribute to CD8 T cell tolerance toward circulating carcinoembryonic antigen in mice

(2012) Bastian Höchst et al.   HEPATOLOGY

Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection

(2012) Victoria M. Velazquez et al.   HEPATOLOGY

Dominance of the CD4+T helper cell response during acute resolving hepatitis A virus infection

(2012) Yan Zhou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type III Interferons, IL-28 and IL-29, Are Increased in Chronic HCV Infection and Induce Myeloid Dendritic Cell-Mediated FoxP3+ Regulatory T Cells

(2012) Angela Dolganiuc et al.   PLoS One

Galectin-9 Ameliorates Con A-Induced Hepatitis by Inducing CD4+CD25low/int Effector T-Cell Apoptosis and Increasing Regulatory T Cell Number

(2012) Kun Lv et al.   PLoS One

The danger theory: 20 years later

(2012) Thomas Pradeu et al.   Frontiers in Immunology

Type I interferons suppress CD4+ T-cell-dependent parasite control during blood-stage Plasmodium infection

(2011) Ashraful Haque et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Host Response to Translocated Microbial Products Predicts Outcomes of Patients With HBV or HCV Infection

(2011) Netanya G. Sandler et al.   GASTROENTEROLOGY

Genetic variation in interleukin 28B with respect to vertical transmission of hepatitis C virus and spontaneous clearance in HCV-infected children

(2011) Ángeles Ruiz-Extremera et al.   HEPATOLOGY

Cross-presentation of antigen by diverse subsets of murine liver cells

(2011) Mohammad R. Ebrahimkhani et al.   HEPATOLOGY

Virus-Induced Transient Immune Suppression and the Inhibition of T Cell Proliferation by Type I Interferon

(2011) H. D. Marshall et al.   JOURNAL OF VIROLOGY

Gut Microbiota Dysbiosis Is Associated with Inflammation and Bacterial Translocation in Mice with CCl4-Induced Fibrosis

(2011) Isabel Gómez-Hurtado et al.   PLoS One

Characteristics and PD-1 expression of peripheral CD4+CD127loCD25hiFoxP3+ Treg cells in chronic HCV infected-patients

(2011) Tao Shen et al.   Virology Journal

The Pore-Forming Toxin Listeriolysin O Mediates a Novel Entry Pathway of L. monocytogenes into Human Hepatocytes

(2011) Stephen Vadia et al.   PLoS Pathogens

Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism

(2010) Sylvie Rabot et al.   FASEB JOURNAL

Genetically engineered, attenuated whole-cell vaccine approaches for malaria

(2010) Ashley Vaughan et al.   Human vaccines & immunotherapeutics

CD40L co-stimulation from CD8+ to CD4+ effector memory T cells supports CD4+ expansion

(2010) Maria Xydia et al.   IMMUNOLOGY AND CELL BIOLOGY

Dynamic Regulation of CD8 T Cell Tolerance Induction by Liver Sinusoidal Endothelial Cells

(2010) A. Schurich et al.   JOURNAL OF IMMUNOLOGY

A Crucial Role for Kupffer Cell-Derived Galectin-9 in Regulation of T Cell Immunity in Hepatitis C Infection

(2010) John A. Mengshol et al.   PLoS One

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

(2010) M. Vijay-Kumar et al.   SCIENCE

Hepatitis A and Hepatitis C Viruses: Divergent Infection Outcomes Marked by Similarities in Induction and Evasion of Interferon Responses

(2010) Lin Qu et al.   SEMINARS IN LIVER DISEASE

TLRs in Hepatic Cellular Crosstalk

(2010) Amelie E. Bigorgne et al.   Gastroenterology Research and Practice

High Efficacy of a Listeria-Based Vaccine against Metastatic Breast Cancer Reveals a Dual Mode of Action

(2009) S. H. Kim et al.   CANCER RESEARCH

MyD88 Signaling in the CNS Is Required for Development of Fatty Acid-Induced Leptin Resistance and Diet-Induced Obesity

(2009) André Kleinridders et al.   Cell Metabolism

Mechanistic insights into immunomodulation by hepatic stellate cells in mice: A critical role of interferon-γ signaling

(2009) Horng-Ren Yang et al.   HEPATOLOGY

Endotoxin uptake in mouse liver is blocked by endotoxin pretreatment through a suppressor of cytokine signaling-1-dependent mechanism

(2009) Melanie J. Scott et al.   HEPATOLOGY

Toll-Like Receptor Engagement Enhances the Immunosuppressive Properties of Human Bone Marrow-Derived Mesenchymal Stem Cells by Inducing Indoleamine-2,3-dioxygenase-1 via Interferon-β and Protein Kinase R

(2009) Christiane A. Opitz et al.   STEM CELLS

Type II fatty acid synthesis is essential only for malaria parasite late liver stage development

(2008) Ashley M. Vaughan et al.   CELLULAR MICROBIOLOGY

Liver sinusoidal endothelial cells veto CD8 T cell activation by antigen-presenting dendritic cells

(2008) Frank A. Schildberg et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Systemic antigen cross-presented by liver sinusoidal endothelial cells induces liver-specific CD8 T-cell retention and tolerization

(2008) Nanette von Oppen et al.   HEPATOLOGY

Role of Kupffer cells in the induction of tolerance of orthotopic liver transplantation in rats

(2008) Yong Chen et al.   LIVER TRANSPLANTATION

Interactions of LSECtin and DC-SIGN/DC-SIGNR with viral ligands: Differential pH dependence, internalization and virion binding

(2008) Thomas Gramberg et al.   VIROLOGY