Guidelines on the diagnosis and treatment of foot infection in persons with diabetes (IWGDF 2019 update)

Diagnosis of infection in the foot in diabetes: a systematic review

(2020) Éric Senneville et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Interventions in the management of infection in the foot in diabetes: a systematic review

(2020) Edgar J. G. Peters et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Factors Predicting Positive Culture in CT-Guided Bone Biopsy Performed for Suspected Osteomyelitis

(2019) Gabriela Beroukhim et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Principles and practice of antibiotic stewardship in the management of diabetic foot infections

(2019) Ilker Uçkay et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Negative pressure wound therapy use in diabetic foot syndrome - from mechanisms of action to clinical practice

(2019) Sebastian Borys et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

A Bibliometric Analysis of Global Research Production Pertaining to Diabetic Foot Ulcers in the Past Ten Years

(2019) Man-Li Zha et al.   Journal of Foot & Ankle Surgery

Pentraxin-3: A new parameter in predicting the severity of diabetic foot infection?

(2019) Safak Ozer Balin et al.   International Wound Journal

Disparities in outcomes of patients admitted with diabetic foot infections

(2019) Tze-Woei Tan et al.   PLoS One

Oral versus Intravenous Antibiotics for Bone and Joint Infection

(2019) Ho-Kwong Li et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparison of microbiological results obtained from per-wound bone biopsies versus transcutaneous bone biopsies in diabetic foot osteomyelitis: a prospective cohort study

(2019) Alice Couturier et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Update on management of diabetic foot ulcers

(2018) Estelle Everett et al.   Annals of the New York Academy of Sciences

Understanding the microbiome of diabetic foot osteomyelitis: insights from molecular and microscopic approaches

(2018) K. Johani et al.   CLINICAL MICROBIOLOGY AND INFECTION

Diabetic Foot Infection: The Role of PET/CT Imaging

(2018) Elite Arnon-Sheleg et al.   CURRENT PHARMACEUTICAL DESIGN

An Overview on Diabetic Foot Infections, including Issues Related to Associated Pain, Hyperglycemia and Limb Ischemia

(2018) Ilker Uckay et al.   CURRENT PHARMACEUTICAL DESIGN

Association between biofilm and multi/extensive drug resistance in diabetic foot infection

(2018) Aslı Vatan et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Concordance Between Bone Pathology and Bone Culture for the Diagnosis of Osteomyelitis in the Presence of Charcot Neuro-Osteoarthropathy

(2018) Tammer Elmarsafi et al.   Journal of Foot & Ankle Surgery

Angiographic assessment of atherosclerotic load at the lower extremity in patients with diabetic foot and charcot neuro-arthropathy

(2018) Mehmet B. Çildağ et al.   Journal of the Chinese Medical Association

Potential of circulatory procalcitonin as a biomarker reflecting inflammation among South Indian diabetic foot ulcers

(2018) Dhamodharan Umapathy et al.   JOURNAL OF VASCULAR SURGERY

Diabetic foot infection: A critical complication

(2018) Jennifer J Hurlow et al.   International Wound Journal

Role of anaerobes in polymicrobial communities and biofilms complicating diabetic foot ulcers

(2018) Steven L Percival et al.   International Wound Journal

Managing diabetic foot infections: a survey of Australasian infectious diseases clinicians

(2018) Robert J. Commons et al.   Journal of Foot and Ankle Research

CODIFI (Concordance in Diabetic Foot Ulcer Infection): a cross-sectional study of wound swab versus tissue sampling in infected diabetic foot ulcers in England

(2018) Andrea Nelson et al.   BMJ Open

The Role of Serum Procalcitonin, Interleukin-6, and Fibrinogen Levels in Differential Diagnosis of Diabetic Foot Ulcer Infection

(2018) Pınar Korkmaz et al.   Journal of Diabetes Research

Antibacterial action of Tropical honey on various bacteria obtained from diabetic foot ulcer

(2018) Ramya Kateel et al.   Complementary Therapies in Clinical Practice

Antimicrobial use of reactive oxygen therapy: current insights

(2018) Mohammad Yousef Memar et al.   Infection and Drug Resistance

A randomized, controlled study to investigate the efficacy and safety of a topical gentamicin-collagen sponge in combination with systemic antibiotic therapy in diabetic patients with a moderate or severe foot ulcer infection

(2018) Ilker Uçkay et al.   BMC INFECTIOUS DISEASES

Remission in diabetic foot infections: Duration of antibiotic therapy and other possible associated factors

(2018) Karim Gariani et al.   DIABETES OBESITY & METABOLISM

Cortical disruption is the most reliable and accurate plain radiographic sign in the diagnosis of diabetic foot osteomyelitis

(2018) F J Álvaro-Afonso et al.   DIABETIC MEDICINE

Culture of Bone Biopsy Specimens Overestimates Rate of Residual Osteomyelitis After Toe or Forefoot Amputation

(2018) B. Mijuskovic et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Level of Agreement With a Multi-Test Approach to the Diagnosis of Diabetic Foot Osteomyelitis

(2018) Andrew J. Meyr et al.   Journal of Foot & Ankle Surgery

Effectiveness of Hyperbaric Oxygen Therapy for the Management of Chronic Osteomyelitis: A Systematic Review of the Literature

(2018) Olga D. Savvidou et al.   ORTHOPEDICS

Added value of MRI to X-ray in guiding the extent of surgical resection in diabetic forefoot osteomyelitis: a review of pathologically proven, surgically treated cases

(2018) Micah Cohen et al.   SKELETAL RADIOLOGY

Hyperbaric oxygen therapy: Antimicrobial mechanisms and clinical application for infections

(2018) Mohammad Yousef Memar et al.   BIOMEDICINE & PHARMACOTHERAPY

Modern management of diabetic foot osteomyelitis. The when, how and why of conservative approaches

(2017) Javier Aragón-Sánchez et al.   Expert Review of Anti-Infective Therapy

Diabetic foot infection: Antibiotic therapy and good practice recommendations

(2017) Nicholas D. Barwell et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Evidence for silver in wound care - meta-analysis of clinical studies from 2000-2015

(2017) Joachim Dissemond et al.   JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT

Effect of cadexomer iodine on the microbial load and diversity of chronic non-healing diabetic foot ulcers complicated by biofilm in vivo

(2017) M. Malone et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Procalcitonin levels and other biochemical parameters in patients with or without diabetic foot complications

(2017) ShathaAbdul Wadood AL-Shammaree et al.   Journal of Research in Medical Sciences

Advanced MR Imaging Techniques for Differentiation of Neuropathic Arthropathy and Osteomyelitis in the Diabetic Foot

(2017) Teodoro Martín Noguerol et al.   RADIOGRAPHICS

Microscopy visualisation confirms multi-species biofilms are ubiquitous in diabetic foot ulcers

(2017) Khalid Johani et al.   International Wound Journal

Next Generation DNA Sequencing of Tissues from Infected Diabetic Foot Ulcers

(2017) M. Malone et al.   EBioMedicine

Predictors of Severity in Diabetic Foot Infections

(2016) Devon Callahan et al.   ANNALS OF VASCULAR SURGERY

Diagnostic Accuracy of Probe to Bone to Detect Osteomyelitis in the Diabetic Foot: A Systematic Review

(2016) Kenrick Lam et al.   CLINICAL INFECTIOUS DISEASES

Editorial Commentary: Probe-to-Bone Test for Detecting Diabetic Foot Osteomyelitis: Rapid, Safe, and Accurate—but for Which Patients?

(2016) Eric Senneville   CLINICAL INFECTIOUS DISEASES

Image-guided percutaneous disc sampling: impact of antecedent antibiotics on yield

(2016) V. Agarwal et al.   CLINICAL RADIOLOGY

Can molecular DNA-based techniques unravel the truth about diabetic foot infections?

(2016) M. Malone et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Interventions in the management of infection in the foot in diabetes: a systematic review

(2016) E. J. Peters et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

IWGDF guidance on the diagnosis and management of foot infections in persons with diabetes

(2016) Benjamin A. Lipsky et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Effectiveness of interventions to enhance healing of chronic ulcers of the foot in diabetes: a systematic review

(2016) F. L. Game et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Tigecycline use in the outpatient parenteral antibiotic therapy setting

(2016) P. R. Ingram et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Antimicrobial stewardship in wound care: a Position Paper from the British Society for Antimicrobial Chemotherapy and European Wound Management Association

(2016) Benjamin A. Lipsky et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Utility of PET/CT with fluorine-18-fluorodeoxyglucose-labeled autologous leukocytes for diagnosing diabetic foot osteomyelitis in patients with Charcot’s neuroarthropathy

(2016) Ashu Rastogi et al.   NUCLEAR MEDICINE COMMUNICATIONS

A Comparison of Tissue versus Swab Culturing of Infected Diabetic Foot Wounds

(2016) Ying Huang et al.   International Journal of Endocrinology

Erythrocyte sedimentation rate and C-reactive protein to monitor treatment outcomes in diabetic foot osteomyelitis

(2016) Suzanne AV van Asten et al.   International Wound Journal

GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines

(2016) Pablo Alonso-Coello et al.   BMJ-British Medical Journal

GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines

(2016) Pablo Alonso-Coello et al.   BMJ-British Medical Journal

Reporting standards of studies and papers on the prevention and management of foot ulcers in diabetes: required details and markers of good quality

(2016) William J Jeffcoate et al.   Lancet Diabetes & Endocrinology

Topical honey for the treatment of diabetic foot ulcer: A systematic review

(2016) Ramya Kateel et al.   Complementary Therapies in Clinical Practice

The role of anaerobes in diabetic foot infections

(2015) Patrick G.P. Charles et al.   ANAEROBE

Novel negative pressure wound therapy with instillation and the management of diabetic foot infections

(2015) Adam P. Dale et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Predictors of Lower-Extremity Amputation in Patients With an Infected Diabetic Foot Ulcer

(2015) Kristy Pickwell et al.   DIABETES CARE

The Anti-Inflammatory and Antibacterial Action of Nanocrystalline Silver and Manuka Honey on the Molecular Alternation of Diabetic Foot Ulcer: A Comprehensive Literature Review

(2015) Ka-Kit Tsang et al.   Evidence-based Complementary and Alternative Medicine

In diabetic foot infections antibiotics are to treat infection, not to heal wounds

(2015) Mohamed Abbas et al.   EXPERT OPINION ON PHARMACOTHERAPY

Automatic detection of diabetic foot complications with infrared thermography by asymmetric analysis

(2015) Chanjuan Liu et al.   JOURNAL OF BIOMEDICAL OPTICS

The Society for Vascular Surgery lower extremity threatened limb classification system based on Wound, Ischemia, and foot Infection (WIfI) correlates with risk of major amputation and time to wound healing

(2015) Luke X. Zhan et al.   JOURNAL OF VASCULAR SURGERY

Can We Stop Antibiotic Therapy When Signs and Symptoms Have Resolved in Diabetic Foot Infection Patients?

(2015) Yuejie Chu et al.   International Journal of Lower Extremity Wounds

Topical oxygen wound therapies for chronic wounds: a review

(2015) J. Dissemond et al.   Journal of Wound Care

Cultures of Diabetic Foot Ulcers Without Clinical Signs of Infection Do Not Predict Outcomes

(2014) Sue E. Gardner et al.   DIABETES CARE

Treating Diabetic Foot Osteomyelitis Primarily With Surgery or Antibiotics: Have We Answered the Question?

(2014) Benjamin A. Lipsky   DIABETES CARE

Six-Week Versus Twelve-Week Antibiotic Therapy for Nonsurgically Treated Diabetic Foot Osteomyelitis: A Multicenter Open-Label Controlled Randomized Study

(2014) Alina Tone et al.   DIABETES CARE

Inter-observer reproducibility of diagnosis of diabetic foot osteomyelitis based on a combination of probe-to-bone test and simple radiography

(2014) Francisco Javier Álvaro-Afonso et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Diagnostic Values for Skin Temperature Assessment to Detect Diabetes-Related Foot Complications

(2014) Jaap J. van Netten et al.   Diabetes Technology & Therapeutics

Assessment of Signs of Foot Infection in Diabetes Patients Using Photographic Foot Imaging and Infrared Thermography

(2014) Constantijn E.V.B. Hazenberg et al.   Diabetes Technology & Therapeutics

Assessing diabetic foot osteomyelitis remission with white blood cell SPECT/CT imaging

(2014) J. Vouillarmet et al.   DIABETIC MEDICINE

Contribution of infection and peripheral artery disease to severity of diabetic foot ulcers in Chinese patients

(2014) D. Hao et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Are Quantitative Bacterial Wound Cultures Useful?

(2014) G. Kallstrom   JOURNAL OF CLINICAL MICROBIOLOGY

Self-Reported Quality of Life and Diabetic Foot Infections

(2014) Katherine M. Raspovic et al.   Journal of Foot & Ankle Surgery

Pathogens Isolated From Deep Soft Tissue and Bone in Patients With Diabetic Foot Infections

(2014) M. Bulent Ertugrul et al.   JOURNAL OF THE AMERICAN PODIATRIC MEDICAL ASSOCIATION

Biofilm-Related Infections: Bridging the Gap between Clinical Management and Fundamental Aspects of Recalcitrance toward Antibiotics

(2014) D. Lebeaux et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

A clinical trial testing the efficacy of PDT in preventing amputation in diabetic patients

(2014) João Paulo Tardivo et al.   Photodiagnosis and Photodynamic Therapy

Wonder of Life (kalanchoe pinnata) leaves to treat diabetic foot infections in Trinidad & Tobago: a case control study

(2014) Shamir O Cawich et al.   TROPICAL DOCTOR

Staphylococcus aureus–Related Diabetic Osteomyelitis

(2014) Olivier Lesens et al.   International Journal of Lower Extremity Wounds

Photodynamic topical antimicrobial therapy for infected foot ulcers in patients with diabetes: a randomized, double-blind, placebo-controlled study—the D.A.N.T.E (Diabetic ulcer Antimicrobial New Topical treatment Evaluation) study

(2013) Edoardo Mannucci et al.   ACTA DIABETOLOGICA

Diagnosing Diabetic Foot Osteomyelitis in Patients Without Signs of Soft Tissue Infection by Coupling Hybrid 67Ga SPECT/CT With Bedside Percutaneous Bone Puncture

(2013) E. Aslangul et al.   DIABETES CARE

Antibiotics Versus Conservative Surgery for Treating Diabetic Foot Osteomyelitis: A Randomized Comparative Trial

(2013) José Luis Lázaro-Martínez et al.   DIABETES CARE

Conservative management of diabetic foot osteomyelitis

(2013) S. Acharya et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Phase 3 study comparing tigecycline and ertapenem in patients with diabetic foot infections with and without osteomyelitis

(2013) Laszlo Lauf et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Current pharmacotherapy options for osteomyelitis: convergences, divergences and lessons to be drawn

(2013) Eric Senneville et al.   EXPERT OPINION ON PHARMACOTHERAPY

Severity of Diabetic Foot Infection and Rate of Limb Salvage

(2013) Dane K. Wukich et al.   FOOT & ANKLE INTERNATIONAL

Diagnosis and Management of Infection in the Diabetic Foot

(2013) Edgar J.G. Peters et al.   MEDICAL CLINICS OF NORTH AMERICA

Evolution of a Diabetic Foot Infection

(2013) Mickaël Tobalem et al.   NEW ENGLAND JOURNAL OF MEDICINE

The ability of the National Early Warning Score (NEWS) to discriminate patients at risk of early cardiac arrest, unanticipated intensive care unit admission, and death

(2013) Gary B. Smith et al.   RESUSCITATION

Phase IIa randomized, placebo-controlled study of antimicrobial photodynamic therapy in bacterially colonized, chronic leg ulcers and diabetic foot ulcers: a new approach to antimicrobial therapy

(2012) S. Morley et al.   BRITISH JOURNAL OF DERMATOLOGY

2012 Infectious Diseases Society of America Clinical Practice Guideline for the Diagnosis and Treatment of Diabetic Foot Infections

(2012) B. A. Lipsky et al.   CLINICAL INFECTIOUS DISEASES

Real time presence of a microbiologist in a multidisciplinary diabetes foot clinic

(2012) Angela N. Paisley et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Diabetes and foot infection: more than double trouble

(2012) Jean-Louis Richard et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Rate of Residual Osteomyelitis after Partial Foot Amputation in Diabetic Patients: A Standardized Method for Evaluating Bone Margins with Intraoperative Culture

(2012) Said Atway et al.   Journal of Foot & Ankle Surgery

Diabetic Musculoskeletal Complications and Their Imaging Mimics

(2012) Jonathan C. Baker et al.   RADIOGRAPHICS

The utility of Gram stains and culture in the management of limb ulcers in persons with diabetes

(2012) Zulfiqarali G Abbas et al.   International Wound Journal

A prospective, non comparative, multicenter study to investigate the effect of cadexomer iodine on bioburden load and other wound characteristics in diabetic foot ulcers

(2012) Jamie A Schwartz et al.   International Wound Journal

Systemic Antibiotic Therapy for Chronic Osteomyelitis in Adults

(2011) B. Spellberg et al.   CLINICAL INFECTIOUS DISEASES

The Effect of Residual Osteomyelitis at the Resection Margin in Patients with Surgically Treated Diabetic Foot Infection

(2011) Todd J. Kowalski et al.   Journal of Foot & Ankle Surgery

Statistical Reliability of Bone Biopsy for the Diagnosis of Diabetic Foot Osteomyelitis

(2011) Andrew J. Meyr et al.   Journal of Foot & Ankle Surgery

Diabetic lower extremity wounds: the rationale for growth factors-based infiltration treatment

(2011) Jorge Berlanga-Acosta   International Wound Journal

Role of bone biopsy specimen culture in the management of diabetic foot osteomyelitis

(2010) T.P. Elamurugan et al.   International Journal of Surgery

Clinical Signs of Infection in Diabetic Foot Ulcers With High Microbial Load

(2009) Sue E. Gardner et al.   Biological Research for Nursing

Needle Puncture and Transcutaneous Bone Biopsy Cultures Are Inconsistent in Patients with Diabetes and Suspected Osteomyelitis of the Foot

(2009) Eric Senneville et al.   CLINICAL INFECTIOUS DISEASES

Hyperbaric oxygen therapy as an anti-infective agent

(2009) Maide Çimşit et al.   Expert Review of Anti-Infective Therapy

Efficacy and safety of sequential intravenous/oral moxifloxacin vs intravenous/oral amoxicillin/clavulanate for complicated skin and skin structure infections

(2009) R. Vick-Fragoso et al.   INFECTION

Is there a role for imaging in the management of patients with diabetic foot?

(2009) Vartan M. Vartanians et al.   SKELETAL RADIOLOGY

Wound Bioburden and Infection-Related Complications in Diabetic Foot Ulcers

(2008) S. E. Gardner et al.   Biological Research for Nursing

Diagnostic Accuracy of the Physical Examination and Imaging Tests for Osteomyelitis Underlying Diabetic Foot Ulcers: Meta‐Analysis

(2008) Marie T. Dinh et al.   CLINICAL INFECTIOUS DISEASES

Outcome of Diabetic Foot Osteomyelitis Treated Nonsurgically: A retrospective cohort study

(2008) E. Senneville et al.   DIABETES CARE

Use of the SINBAD Classification System and Score in Comparing Outcome of Foot Ulcer Management on Three Continents

(2008) P. Ince et al.   DIABETES CARE

Risk factors for developing osteomyelitis in patients with diabetic foot wounds

(2008) Lawrence A. Lavery et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Diabetic foot osteomyelitis: a progress report on diagnosis and a systematic review of treatment

(2008) A. R. Berendt et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Primarily non-surgical management of osteomyelitis of the foot in diabetes

(2008) F. L. Game et al.   DIABETOLOGIA

Outcomes of surgical treatment of diabetic foot osteomyelitis: a series of 185 patients with histopathological confirmation of bone involvement

(2008) F. J. Aragón-Sánchez et al.   DIABETOLOGIA

Prediction of outcome in individuals with diabetic foot ulcers: focus on the differences between individuals with and without peripheral arterial disease. The EURODIALE Study

(2008) L. Prompers et al.   DIABETOLOGIA

The pro-inflammatory environment in recalcitrant diabetic foot wounds

(2008) Jorge Berlanga Acosta et al.   International Wound Journal

GRADE: an emerging consensus on rating quality of evidence and strength of recommendations

(2008) Gordon H Guyatt et al.   BMJ-British Medical Journal