Kinesin-1-mediated axonal transport of CB1 receptors is required for cannabinoid-dependent axonal growth and guidance

Δ9-tetrahydrocannabinol and 2-AG decreases neurite outgrowth and differentially affects ERK1/2 and Akt signaling in hiPSC-derived cortical neurons

(2020) Carole Shum et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Neuronal KIF5b deletion induces striatum -dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors

(2019) Lucas E. Cromberg et al.   JOURNAL OF NEUROCHEMISTRY

The C-terminal helix 9 motif in rat cannabinoid receptor type 1 regulates axonal trafficking and surface expression

(2019) Alexandra Fletcher-Jones et al.   eLife

Axonal transport: Driving synaptic function

(2019) Pedro Guedes-Dias et al.   SCIENCE

Interference with the Cannabinoid Receptor CB1R Results in Miswiring of GnRH3 and AgRP1 Axons in Zebrafish Embryos

(2019) Giulia Zuccarini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cell guidance ligands, receptors and complexes – orchestrating signalling in time and space

(2019) Daniel Rozbesky et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Understanding axon guidance: are we nearly there yet?

(2018) Esther T. Stoeckli   DEVELOPMENT

Proteasome stress leads to APP axonal transport defects by promoting its amyloidogenic processing in lysosomes

(2018) María Gabriela Otero et al.   JOURNAL OF CELL SCIENCE

The F238L Point Mutation in the Cannabinoid Type 1 Receptor Enhances Basal Endocytosis via Lipid Rafts

(2018) Melanie Wickert et al.   Frontiers in Molecular Neuroscience

Rapid Assembly of Presynaptic Materials behind the Growth Cone in Dopaminergic Neurons Is Mediated by Precise Regulation of Axonal Transport

(2018) David M. Lipton et al.   Cell Reports

Cannabinoid Receptors Modulate Neuronal Morphology and AnkyrinG Density at the Axon Initial Segment

(2017) Mónica Tapia et al.   Frontiers in Cellular Neuroscience

Deficits in axon-associated proteins in prefrontal white matter in bipolar disorder but not schizophrenia

(2016) Li Shao et al.   BIPOLAR DISORDERS

KIF5A de novomutation associated with myoclonic seizures and neonatal onset progressive leukoencephalopathy

(2016) M. Rydzanicz et al.   CLINICAL GENETICS

Calsyntenin 1-mediated trafficking of axon guidance receptors regulates the switch in axonal responsiveness at a choice point

(2016) Tobias A. Alther et al.   DEVELOPMENT

Tau Isoforms Imbalance Impairs the Axonal Transport of the Amyloid Precursor Protein in Human Neurons

(2016) Valentina Lacovich et al.   JOURNAL OF NEUROSCIENCE

The Dynamic Localization of Cytoplasmic Dynein in Neurons Is Driven by Kinesin-1

(2016) Alison E. Twelvetrees et al.   NEURON

JIP3 Activates Kinesin-1 Motility to Promote Axon Elongation

(2015) Dana Watt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recurrent KIF5C mutation leading to frontal pachygyria without microcephaly

(2015) Mara Cavallin et al.   NEUROGENETICS

Genomic Variants and Variations in Malformations of Cortical Development

(2015) Saumya S. Jamuar et al.   PEDIATRIC CLINICS OF NORTH AMERICA

The Cannabinoid Receptor CB1 Interacts with the WAVE1 Complex and Plays a Role in Actin Dynamics and Structural Plasticity in Neurons

(2015) Christian Njoo et al.   PLOS BIOLOGY

Fast axonal transport of the proteasome complex depends on membrane interaction and molecular motor function

(2014) M. G. Otero et al.   JOURNAL OF CELL SCIENCE

Involvement of the kinesin family membersKIF4AandKIF5Cin intellectual disability and synaptic function

(2014) Marjolein H Willemsen et al.   JOURNAL OF MEDICAL GENETICS

JIP1 Mediates Anterograde Transport of Rab10 Cargos during Neuronal Polarization

(2014) C.-Y. Deng et al.   JOURNAL OF NEUROSCIENCE

UV Irradiation Accelerates Amyloid Precursor Protein (APP) Processing and Disrupts APP Axonal Transport

(2014) A. Almenar-Queralt et al.   JOURNAL OF NEUROSCIENCE

Malformations of cortical development: clinical features and genetic causes

(2014) Renzo Guerrini et al.   LANCET NEUROLOGY

Axonal Transport: Cargo-Specific Mechanisms of Motility and Regulation

(2014) Sandra Maday et al.   NEURON

A Molecular Basis for Nicotine as a Gateway Drug

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

EphB receptor forward signaling regulates area-specific reciprocal thalamic and cortical axon pathfinding

(2014) Michael A. Robichaux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cannabinoid-induced actomyosin contractility shapes neuronal morphology and growth

(2014) Alexandre B Roland et al.   eLife

Mutations in TUBG1, DYNC1H1, KIF5C and KIF2A cause malformations of cortical development and microcephaly

(2013) Karine Poirier et al.   NATURE GENETICS

Mechanisms controlling the guidance of thalamocortical axons through the embryonic forebrain

(2012) Zoltán Molnár et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Molecular Motor KIF5A Is Essential for GABAA Receptor Transport, and KIF5A Deletion Causes Epilepsy

(2012) Kazuo Nakajima et al.   NEURON

Endocannabinoid Signaling and Synaptic Function

(2012) Pablo E. Castillo et al.   NEURON

Diagnostic Exome Sequencing in Persons with Severe Intellectual Disability

(2012) Joep de Ligt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Subpixel colocalization reveals amyloid precursor protein-dependent kinesin-1 and dynein association with axonal vesicles

(2012) L. Szpankowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

JNK/stress-activated protein kinase associated protein 1 is required for early development of telencephalic commissures in embryonic brains

(2011) Ik-Hyun Cho et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Concerted Action of CB1 Cannabinoid Receptor and Deleted in Colorectal Cancer in Axon Guidance

(2011) A. Argaw et al.   JOURNAL OF NEUROSCIENCE

Inputs to the Dorsal Striatum of the Mouse Reflect the Parallel Circuit Architecture of the Forebrain

(2011) Weixing X. Pan et al.   Frontiers in Neuroanatomy

Requirement of cannabinoid CB1 receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections

(2010) Chia-Shan Wu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies

(2010) Tomás L. Falzone et al.   HUMAN MOLECULAR GENETICS

Spatio-temporal Rho GTPase signaling - where are we now?

(2010) O. Pertz   JOURNAL OF CELL SCIENCE

Differential Subcellular Recruitment of Monoacylglycerol Lipase Generates Spatial Specificity of 2-Arachidonoyl Glycerol Signaling during Axonal Pathfinding

(2010) E. Keimpema et al.   JOURNAL OF NEUROSCIENCE

Trafficking Guidance Receptors

(2010) B. Winckler et al.   Cold Spring Harbor Perspectives in Biology

Signaling from Axon Guidance Receptors

(2010) G. J. Bashaw et al.   Cold Spring Harbor Perspectives in Biology

Axonal Stress Kinase Activation and Tau Misbehavior Induced by Kinesin-1 Transport Defects

(2009) T. L. Falzone et al.   JOURNAL OF NEUROSCIENCE

Kinesin superfamily motor proteins and intracellular transport

(2009) Nobutaka Hirokawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The type 1 cannabinoid receptor is highly expressed in embryonic cortical projection neurons and negatively regulates neurite growthin vitro

(2008) Tania Vitalis et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning

(2008) J. Mulder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA