Deficiency of Parkinson’s disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation

PARP-1 involvement in neurodegeneration: A focus on Alzheimer’s and Parkinson’s diseases

(2015) Sara Martire et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease

(2015) Alicia M. Pickrell et al.   NEURON

Hexokinase II Binding to Mitochondria Is Necessary for Kupffer Cell Activation and Is Potentiated by Ethanol Exposure

(2014) Nataly Shulga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reactive Oxygen Species-Mediated DJ-1 Monomerization Modulates Intracellular Trafficking Involving Karyopherin β2

(2014) Benny Björkblom et al.   MOLECULAR AND CELLULAR BIOLOGY

Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis

(2014) S. A. Andrabi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ARTD1/PARP1 Negatively Regulates Glycolysis by Inhibiting Hexokinase 1 Independent of NAD + Depletion

(2014) Elise Fouquerel et al.   Cell Reports

Cellular NAD depletion and decline of SIRT1 activity play critical roles in PARP-1-mediated acute epileptic neuronal death in vitro

(2013) Shengjun Wang et al.   BRAIN RESEARCH

Implications of enzyme deficiencies on mitochondrial energy metabolism and reactive oxygen species formation of neurons involved in rotenone-induced Parkinson's disease: a model-based analysis

(2013) Nikolaus Berndt et al.   FEBS Journal

Induction of mitochondrial dysfunction by poly(ADP-ribose) polymer: Implication for neuronal cell death

(2013) Seung-Hoon Baek et al.   MOLECULES AND CELLS

Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss

(2013) Yunjong Lee et al.   NATURE NEUROSCIENCE

The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy

(2013) Victoria S Burchell et al.   NATURE NEUROSCIENCE

PARP-1 Inhibitor, DPQ, Attenuates LPS-Induced Acute Lung Injury through Inhibiting NF-κB-Mediated Inflammatory Response

(2013) Gang Wang et al.   PLoS One

Beyond ubiquitination: the atypical functions of Fbxo7 and other F-box proteins

(2013) D. E. Nelson et al.   Open Biology

The Role of PARP-1 and PARP-2 Enzymes in Metabolic Regulation and Disease

(2012) Péter Bai et al.   Cell Metabolism

PARP-1 Inhibitors DPQ and PJ-34 Negatively Modulate Proinflammatory Commitment of Human Glioblastoma Cells

(2012) Marina Scalia et al.   NEUROCHEMICAL RESEARCH

HtrA2 deficiency causes mitochondrial uncoupling through the F 1 F 0 -ATP synthase and consequent ATP depletion

(2012) H Plun-Favreau et al.   Cell Death & Disease

Toxin Models of Mitochondrial Dysfunction in Parkinson's Disease

(2011) Terina N. Martinez et al.   ANTIOXIDANTS & REDOX SIGNALING

Assessing mitochondrial dysfunction in cells

(2011) Martin D. Brand et al.   BIOCHEMICAL JOURNAL

β-amyloid activates PARP causing astrocytic metabolic failure and neuronal death

(2011) Rosella Abeti et al.   BRAIN

Phosphorylation of HtrA2 by cyclin-dependent kinase-5 is important for mitochondrial function

(2011) J C Fitzgerald et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial ATP synthase: architecture, function and pathology

(2011) An I. Jonckheere et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Succinate Dehydrogenase Is a Direct Target of Sirtuin 3 Deacetylase Activity

(2011) Lydia W. S. Finley et al.   PLoS One

Bioenergetic Consequences of PINK1 Mutations in Parkinson Disease

(2011) Andrey Yurevich Abramov et al.   PLoS One

The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways

(2010) Riekelt H. Houtkooper et al.   ENDOCRINE REVIEWS

Targeting mitochondrial dysfunction in neurodegenerative disease: Part II

(2010) Victoria S Burchell et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The Genetics of Parkinson Disease

(2010) Lynn M. Bekris et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

NAD+ Depletion Is Necessary and Sufficient forPoly(ADP-Ribose) Polymerase-1-Mediated Neuronal Death

(2010) C. C. Alano et al.   JOURNAL OF NEUROSCIENCE

Impaired mitochondrial bioenergetics determines glutamate-induced delayed calcium deregulation in neurons

(2009) Andrey Y. Abramov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-Induced Cell Death

(2009) Sonia Gandhi et al.   MOLECULAR CELL

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Mechanisms underlying the loss of mitochondrial membrane potential in glutamate excitotoxicity

(2008) Andrey Y. Abramov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Inhibition of the activity of poly (ADP-ribose) polymerase reduces heart ischaemia/reperfusion injuryviasuppressing JNK-mediated AIF translocation

(2008) Zhao-Feng Song et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mitochondria in the aetiology and pathogenesis of Parkinson's disease

(2008) Anthony HV Schapira   LANCET NEUROLOGY

FBXO7 mutations cause autosomal recessive, early-onset parkinsonian-pyramidal syndrome

(2008) A. D. Fonzo et al.   NEUROLOGY

The coenzyme Q10 status of the brain regions of Parkinson’s disease patients

(2008) Iain P. Hargreaves et al.   NEUROSCIENCE LETTERS

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

(2008) I. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

(2008) B.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular NAD Replenishment Confers Marked Neuroprotection Against Ischemic Cell Death

(2008) Suping Wang et al.   STROKE

Complex I deficiency in Parkinson's disease frontal cortex

(2007) W. Davis Parker et al.   BRAIN RESEARCH

Poly(ADP-ribose)polymerase 1 (PARP-1) and postischemic brain damage

(2007) F MORONI   CURRENT OPINION IN PHARMACOLOGY