Beyond ubiquitination: the atypical functions of Fbxo7 and other F-box proteins

Cand1 Promotes Assembly of New SCF Complexes through Dynamic Exchange of F Box Proteins

(2013) Nathan W. Pierce et al.   CELL

Proteasome Regulation by ADP-Ribosylation

(2013) Park F. Cho-Park et al.   CELL

FBXO7 Immunoreactivity in α-Synuclein—Containing Inclusions in Parkinson Disease and Multiple System Atrophy

(2013) Tianna Zhao et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy

(2013) Victoria S Burchell et al.   NATURE NEUROSCIENCE

Mechanisms and function of substrate recruitment by F-box proteins

(2013) Jeffrey R. Skaar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CAND1 controls in vivo dynamics of the cullin 1-RING ubiquitin ligase repertoire

(2013) Shuangding Wu et al.   Nature Communications

Mitochondrial Biology and Parkinson's Disease

(2013) C. Perier et al.   Cold Spring Harbor Perspectives in Medicine

α-Synuclein oligomers and clinical implications for Parkinson disease

(2012) Lorraine V. Kalia et al.   ANNALS OF NEUROLOGY

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Knockdown of HURP inhibits the proliferation of hepacellular carcinoma cells via downregulation of gankyrin and accumulation of p53

(2012) Tzu-Ching Kuo et al.   BIOCHEMICAL PHARMACOLOGY

Identification of F-box only protein 7 as a negative regulator of NF-kappaB signalling

(2012) Hendrik J. Kuiken et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Genetic Loci Implicated in Erythroid Differentiation and Cell Cycle Regulation Are Associated With Red Blood Cell Traits

(2012) Keyue Ding et al.   MAYO CLINIC PROCEEDINGS

Seventy-five genetic loci influencing the human red blood cell

(2012) Pim van der Harst et al.   NATURE

New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs

(2012) Bryan A. Gibson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ensembl 2013

(2012) Paul Flicek et al.   NUCLEIC ACIDS RESEARCH

The Role of Alpha-Synuclein Oligomerization and Aggregation in Cellular and Animal Models of Parkinson’s Disease

(2012) Oi Wan Wan et al.   PLoS One

A Conserved F Box Regulatory Complex Controls Proteasome Activity in Drosophila

(2011) Maya Bader et al.   CELL

Drosophila BRUCE inhibits apoptosis through non-lysine ubiquitination of the IAP-antagonist REAPER

(2011) C Domingues et al.   CELL DEATH AND DIFFERENTIATION

HURP Regulates Chromosome Congression by Modulating Kinesin Kif18A Function

(2011) Fan Ye et al.   CURRENT BIOLOGY

A Competitive Binding Mechanism between Skp1 and Exportin 1 (CRM1) Controls the Localization of a Subset of F-box Proteins

(2011) David E. Nelson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Knockdown of Fbxo7 reveals its regulatory role in proliferation and differentiation of haematopoietic precursor cells

(2011) E. K. Meziane et al.   JOURNAL OF CELL SCIENCE

Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1

(2011) Liliane Glauser et al.   JOURNAL OF NEUROCHEMISTRY

Calmodulin Antagonizes a Calcium-Activated SCF Ubiquitin E3 Ligase Subunit, FBXL2, To Regulate Surfactant Homeostasis

(2011) B. B. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

Non–SCF-type F-box protein Roy1/Ymr258c interacts with a Rab5-like GTPase Ypt52 and inhibits Ypt52 function

(2011) Yuan Liu et al.   MOLECULAR BIOLOGY OF THE CELL

Expression of Fbxo7 in Haematopoietic Progenitor Cells Cooperates with p53 Loss to Promote Lymphomagenesis

(2011) Mikhail Lomonosov et al.   PLoS One

Structure and function of WD40 domain proteins

(2011) Chao Xu et al.   Protein & Cell

Switching cyclin D-Cdk4 kinase activity on and off

(2010) Stacy Blain   CELL CYCLE

A novel F-box protein is required for caspase activation during cellular remodeling in Drosophila

(2010) M. Bader et al.   DEVELOPMENT

The ubiquitous role of ubiquitin in the DNA damage response

(2010) Abdallah Al-Hakim et al.   DNA REPAIR

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

(2010) Atsushi Tanaka et al.   JOURNAL OF CELL BIOLOGY

The Steady-State Repertoire of Human SCF Ubiquitin Ligase Complexes Does Not Require Ongoing Nedd8 Conjugation

(2010) J. Eugene Lee et al.   MOLECULAR & CELLULAR PROTEOMICS

Molecular Basis for Lysine Specificity in the Yeast Ubiquitin-Conjugating Enzyme Cdc34

(2010) M. Sadowski et al.   MOLECULAR AND CELLULAR BIOLOGY

Lysosomal function in macromolecular homeostasis and bioenergetics in Parkinson's disease

(2010) Lonnie Schneider et al.   Molecular Neurodegeneration

Early-onset L-dopa-responsive parkinsonism with pyramidal signs due to ATP13A2, PLA2G6, FBXO7 and spatacsin mutations

(2010) Coro Paisán-Ruiz et al.   MOVEMENT DISORDERS

Novel ATP13A2 (PARK9) homozygous mutation in a family with marked phenotype variability

(2010) Lucio Santoro et al.   NEUROGENETICS

The Mitochondrial Fusion-Promoting Factor Mitofusin Is a Substrate of the PINK1/Parkin Pathway

(2010) Angela C. Poole et al.   PLoS One

Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin

(2010) E. Ziviani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Identification of a conserved F-box protein 6 interactor essential for endocytosis and cytokinesis in fission yeast

(2009) Isabelle Jourdain et al.   BIOCHEMICAL JOURNAL

The emerging complexity of protein ubiquitination

(2009) David Komander   BIOCHEMICAL SOCIETY TRANSACTIONS

A critical evaluation of the ubiquitin–proteasome system in Parkinson's disease

(2009) Casey Cook et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A Requirement for Cyclin-Dependent Kinase 6 in Thymocyte Development and Tumorigenesis

(2009) M. G. Hu et al.   CANCER RESEARCH

SnapShot: F Box Proteins II

(2009) Jeffrey R. Skaar et al.   CELL

NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain

(2009) E Laplantine et al.   EMBO JOURNAL

Lessons from Fungal F-Box Proteins

(2009) Wilfried Jonkers et al.   EUKARYOTIC CELL

Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF- B signaling

(2009) D. Sha et al.   HUMAN MOLECULAR GENETICS

Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities

(2009) Kasper Fugger et al.   JOURNAL OF CELL BIOLOGY

Single Nigrostriatal Dopaminergic Neurons Form Widely Spread and Highly Dense Axonal Arborizations in the Neostriatum

(2009) W. Matsuda et al.   JOURNAL OF NEUROSCIENCE

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Impaired Colonization and Infection of Tomato Roots by the Δfrp1 Mutant of Fusarium oxysporum Correlates with Reduced CWDE Gene Expression

(2009) Wilfried Jonkers et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage

(2009) Manas K. Santra et al.   NATURE

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

(2009) Nicole Soranzo et al.   NATURE GENETICS

Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NF B

(2009) T. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide Linkage Analysis of a Parkinsonian-Pyramidal Syndrome Pedigree by 500 K SNP Arrays

(2008) Seyedmehdi Shojaee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

PINK1 controls mitochondrial localization of Parkin through direct phosphorylation

(2008) Yongsung Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Defining the role of Emi1 in the DNA replication–segregation cycle

(2008) Barbara Di Fiore et al.   CHROMOSOMA

Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1

(2008) Takashi Yasukawa et al.   EMBO JOURNAL

Expression of the Muscle Atrophy Factor Muscle Atrophy F-Box Is Suppressed by Testosterone

(2008) Weidong Zhao et al.   ENDOCRINOLOGY

Structure of a Conserved Dimerization Domain within the F-box Protein Fbxo7 and the PI31 Proteasome Inhibitor

(2008) Rebecca Kirk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

(2008) Mathieu J.M. Bertrand et al.   MOLECULAR CELL

FBXO7 mutations cause autosomal recessive, early-onset parkinsonian-pyramidal syndrome

(2008) A. D. Fonzo et al.   NEUROLOGY

Both cIAP1 and cIAP2 regulate TNF -mediated NF- B activation

(2008) D. J. Mahoney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA