The Genetics of Parkinson Disease

Genome-Wide Association Study Confirms SNPs inSNCAand theMAPTRegion as Common Risk Factors for Parkinson Disease

(2010) Todd L. Edwards et al.   ANNALS OF HUMAN GENETICS

The Role of Glucocerebrosidase Mutations in Parkinson Disease and Lewy Body Disorders

(2010) Arash Velayati et al.   Current Neurology and Neuroscience Reports

Imaging Approaches to Parkinson Disease

(2010) D. J. Brooks   JOURNAL OF NUCLEAR MEDICINE

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

(2010) Taye H Hamza et al.   NATURE GENETICS

A comprehensive analysis of deletions, multiplications, and copy number variations in PARK2

(2010) D. M. Kay et al.   NEUROLOGY

Association of Glucocerebrosidase Mutations With Dementia With Lewy Bodies

(2009) Lorraine N. Clark et al.   ARCHIVES OF NEUROLOGY

Parkinson's disease: from monogenic forms to genetic susceptibility factors

(2009) S. Lesage et al.   HUMAN MOLECULAR GENETICS

LRRK2gene variation and its contribution to Parkinson disease

(2009) Coro Paisán-Ruiz   HUMAN MUTATION

Parkin and PINK1 mutations in early-onset Parkinson's disease: comprehensive screening in publicly available cases and control

(2009) J Brooks et al.   JOURNAL OF MEDICAL GENETICS

LRRK2mutations and risk variants in Japanese patients with Parkinson's disease

(2009) Cyrus P. Zabetian et al.   MOVEMENT DISORDERS

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

(2009) Wataru Satake et al.   NATURE GENETICS

Genome-wide association study reveals genetic risk underlying Parkinson's disease

(2009) Javier Simón-Sánchez et al.   NATURE GENETICS

Parkin dosage mutations have greater pathogenicity in familial PD than simple sequence mutations

(2009) N. Pankratz et al.   NEUROLOGY

Leucine-Rich Repeat Kinase 2 Regulates the Progression of Neuropathology Induced by Parkinson's-Disease-Related Mutant α-synuclein

(2009) Xian Lin et al.   NEURON

Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

(2009) E. Sidransky et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mutations in the GIGYF2 (TNRC15) Gene at the PARK11 Locus in Familial Parkinson Disease

(2008) Corinne Lautier et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic association between α-synuclein and idiopathic parkinson's disease

(2008) Denise M. Kay et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Analysis of Lrrk2 R1628P as a risk factor for Parkinson's disease

(2008) Owen A. Ross et al.   ANNALS OF NEUROLOGY

Characterization of PLA2G6 as a locus for dystonia-parkinsonism

(2008) Coro Paisan-Ruiz et al.   ANNALS OF NEUROLOGY

Molecular Basis for the Structural Instability of Human DJ-1 Induced by the L166P Mutation Associated with Parkinson’s Disease†

(2008) Peter C. Anderson et al.   BIOCHEMISTRY

Significance of the parkin and PINK1gene in Jordanian families with incidences of young-onset and juvenile parkinsonism

(2008) Ronny Myhre et al.   BMC Neurology

Structural insights on physiological functions and pathological effects of α-synuclein

(2008) Marco Bisaglia et al.   FASEB JOURNAL

Parkinson’s disease: A genetic perspective

(2008) Andrea C. Belin et al.   FEBS Journal

Genomewide association study for susceptibility genes contributing to familial Parkinson disease

(2008) Nathan Pankratz et al.   HUMAN GENETICS

Gaucher disease: mutation and polymorphism spectrum in the glucocerebrosidase gene (GBA)

(2008) Kathleen S. Hruska et al.   HUMAN MUTATION

FTDP-17 Mutations in Tau Alter the Regulation of Microtubule Dynamics

(2008) Adria C. LeBoeuf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

(2008) Daniel G Healy et al.   LANCET NEUROLOGY

FBXO7 mutations cause autosomal recessive, early-onset parkinsonian-pyramidal syndrome

(2008) A. D. Fonzo et al.   NEUROLOGY

Lrrk2 R1441C parkinsonism is clinically similar to sporadic Parkinson disease

(2008) K. Haugarvoll et al.   NEUROLOGY

DJ-1 Modulates α-Synuclein Aggregation State in a Cellular Model of Oxidative Stress: Relevance for Parkinson's Disease and Involvement of HSP70

(2008) Sara Batelli et al.   PLoS One

Structural effects of Parkinson's disease linked DJ-1 mutations

(2008) Gaetano Malgieri et al.   PROTEIN SCIENCE

Glial reactions in Parkinson's disease

(2007) Patrick L. McGeer et al.   MOVEMENT DISORDERS