A siRNA screen reveals the prosurvival effect of protein kinase A activation in conditions of unresolved endoplasmic reticulum stress

Pharmacological activation of AMPK prevents Drp1-mediated mitochondrial fission and alleviates endoplasmic reticulum stress-associated endothelial dysfunction

(2015) Jia Li et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

MAPL SUMOylation of Drp1 Stabilizes an ER/Mitochondrial Platform Required for Cell Death

(2015) Julien Prudent et al.   MOLECULAR CELL

Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells

(2015) S Saveljeva et al.   Cell Death & Disease

Endoplasmic Reticulum Stress-Activated Cell Reprogramming in Oncogenesis

(2015) E. Chevet et al.   Cancer Discovery

Stress Responses from the Endoplasmic Reticulum in Cancer

(2015) Hironori Kato et al.   Frontiers in Oncology

Loss of Prkar1a leads to Bcl-2 family protein induction and cachexia in mice

(2014) L Gangoda et al.   CELL DEATH AND DIFFERENTIATION

mTOR pathway is activated by PKA in adrenocortical cells and participates in vivo to apoptosis resistance in primary pigmented nodular adrenocortical disease (PPNAD)

(2014) Cyrille de Joussineau et al.   HUMAN MOLECULAR GENETICS

Delayed Ras/PKA signaling augments the unfolded protein response

(2014) D. Pincus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis

(2014) M. Lu et al.   SCIENCE

RIPK1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved ER stress conditions

(2014) Y Estornes et al.   Cell Death & Disease

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

CREB-binding protein (CBP) regulates β-adrenoceptor (β-AR)−mediated apoptosis

(2013) Y Y Lee et al.   CELL DEATH AND DIFFERENTIATION

RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition

(2013) Y Dondelinger et al.   CELL DEATH AND DIFFERENTIATION

AMPK Regulates ER Morphology and Function in Stressed Pancreatic β-Cells via Phosphorylation of DRP1

(2013) Jakob D. Wikstrom et al.   MOLECULAR ENDOCRINOLOGY

The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress

(2012) Richard Jäger et al.   BIOLOGY OF THE CELL

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

Mitochondrial outer membrane permeabilization during apoptosis: The role of mitochondrial fission

(2011) Thomas Landes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The PKA paradox: Is Bim the answer?

(2011) Andrew M. Coley et al.   CELL CYCLE

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Integrating stress signals at the endoplasmic reticulum: The BCL-2 protein family rheostat

(2010) Diego Rodriguez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Targeting ER stress induced apoptosis and inflammation in cancer

(2010) Tom Verfaillie et al.   CANCER LETTERS

Cyclic-AMP-dependent protein kinase A regulates apoptosis by stabilizing the BH3-only protein Bim

(2010) Diane Moujalled et al.   EMBO REPORTS

Regulation of the autophagy protein LC3 by phosphorylation

(2010) Salvatore J. Cherra et al.   JOURNAL OF CELL BIOLOGY

Specificity and spatial dynamics of protein kinase A signaling organized by A-kinase-anchoring proteins

(2010) Guillaume Pidoux et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Mouse models of altered protein kinase A signaling

(2009) Lawrence S Kirschner et al.   ENDOCRINE-RELATED CANCER

The PKARIα Subunit of Protein Kinase A Modulates the Activation of p90RSK1and Its Function

(2009) Deepti Chaturvedi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

(2009) Naotada Ishihara et al.   NATURE CELL BIOLOGY

Targeted Deletion of Prkar1a Reveals a Role for Protein Kinase A in Mesenchymal-to-Epithelial Transition

(2008) K. S. Nadella et al.   CANCER RESEARCH

Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

(2008) Ann Cassidy-Stone et al.   DEVELOPMENTAL CELL

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY