Andrographolide inhibits prostate cancer by targeting cell cycle regulators, CXCR3 and CXCR7 chemokine receptors

Andrographolide activates the canonical Wnt signalling pathway by a mechanism that implicates the non-ATP competitive inhibition of GSK-3β: autoregulation of GSK-3βin vivo

(2015) Cheril Tapia-Rojas et al.   BIOCHEMICAL JOURNAL

Loss of Notch1-dependent p21Waf1/Cip1expression influences the Notch1 outcome in tumorigenesis

(2014) Samantha Cialfi et al.   CELL CYCLE

Bioavailability of andrographolide and protection against carbon tetrachloride-induced oxidative damage in rats

(2014) Haw-Wen Chen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Andrographolide downregulates the v-Src and Bcr-Abl oncoproteins and induces Hsp90 cleavage in the ROS-dependent suppression of cancer malignancy

(2013) Sheng-Hung Liu et al.   BIOCHEMICAL PHARMACOLOGY

Inhibition of PI3K/Akt Pathway Impairs G2/M Transition of Cell Cycle in Late Developing Progenitors of the Avian Embryo Retina

(2013) Isis Moraes Ornelas et al.   PLoS One

CXCR4/CXCL12 Axis in Non Small Cell Lung Cancer (NSCLC) Pathologic Roles and Therapeutic Potential

(2013) Ori Wald et al.   Theranostics

Developing S-phase control

(2012) R. J. Duronio   GENES & DEVELOPMENT

Inactivation of PI3K/Akt signaling mediates proliferation inhibition and G2/M phase arrest induced by andrographolide in human glioblastoma cells

(2012) Yanchun Li et al.   LIFE SCIENCES

Andrographolide Inhibits Oral Squamous Cell Carcinogenesis through NF-κB Inactivation

(2011) L.-J. Wang et al.   JOURNAL OF DENTAL RESEARCH

Andrographolide Sensitizes Ras-Transformed Cells to Radiation in vitro and in vivo

(2010) Shih-Kai Hung et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Andrographolide Enhances Nuclear Factor-κB Subunit p65 Ser536Dephosphorylation through Activation of Protein Phosphatase 2A in Vascular Smooth Muscle Cells

(2010) Cheng Y. Hsieh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bioavailability Challenges Associated with Development of Anti-Cancer Phenolics

(2010) S. Gao et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

The Roles of Cyclin A2, B1, and B2 in Early and Late Mitotic Events

(2010) Delquin Gong et al.   MOLECULAR BIOLOGY OF THE CELL

Emerging roles of chemokines in prostate cancer

(2009) David Vindrieux et al.   ENDOCRINE-RELATED CANCER

Clinical and biological significance of CXCR5 expressed by prostate cancer specimens and cell lines

(2009) Shailesh Singh et al.   INTERNATIONAL JOURNAL OF CANCER

Inhibition of cell-cycle progression in human colorectal carcinoma Lovo cells by andrographolide

(2008) Ming-Der Shi et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Amelioratory effect of Andrographis paniculata Nees on liver, kidney, heart, lung and spleen during nicotine induced oxidative stress

(2008) Sreeparna Neogy et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Plant-derived compounds in clinical trials

(2007) A SAKLANI et al.   DRUG DISCOVERY TODAY