An evolutionary framework for treating pediatric sarcomas

Assessment of circulating tumor DNA in pediatric solid tumors: The promise of liquid biopsies

(2019) Samuel D. Abbou et al.   PEDIATRIC BLOOD & CANCER

Multidrug cancer therapy in metastatic castrate-resistant prostate cancer: An evolution-based strategy

(2019) Jeffrey B West et al.   CLINICAL CANCER RESEARCH

First Strike–Second Strike Strategies in Metastatic Cancer: Lessons from the Evolutionary Dynamics of Extinction

(2019) Robert A. Gatenby et al.   CANCER RESEARCH

Randomized Phase II Trial of Bevacizumab or Temsirolimus in Combination With Chemotherapy for First Relapse Rhabdomyosarcoma: A Report From the Children’s Oncology Group

(2019) Leo Mascarenhas et al.   JOURNAL OF CLINICAL ONCOLOGY

Maintenance low-dose chemotherapy in patients with high-risk (HR) rhabdomyosarcoma (RMS): A report from the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG).

(2018) Gianni Bisogno et al.   JOURNAL OF CLINICAL ONCOLOGY

Wicked evolution: Can we address the sociobiological dilemma of pesticide resistance?

(2018) Fred Gould et al.   SCIENCE

High-Dose Chemotherapy and Blood Autologous Stem-Cell Rescue Compared With Standard Chemotherapy in Localized High-Risk Ewing Sarcoma: Results of Euro-E.W.I.N.G.99 and Ewing-2008

(2018) Jeremy Whelan et al.   JOURNAL OF CLINICAL ONCOLOGY

Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors

(2018) Nathaniel D. Anderson et al.   SCIENCE

The addition of cixutumumab or temozolomide to intensive multiagent chemotherapy is feasible but does not improve outcome for patients with metastatic rhabdomyosarcoma

(2018) Suman Malempati et al.   CANCER

Orthotopic patient-derived xenografts of paediatric solid tumours

(2017) Elizabeth Stewart et al.   NATURE

Natural selection shaped the rise and fall of passenger pigeon genomic diversity

(2017) Gemma G. R. Murray et al.   SCIENCE

Integrating evolutionary dynamics into treatment of metastatic castrate-resistant prostate cancer

(2017) Jingsong Zhang et al.   Nature Communications

Size-based detection of sarcoma circulating tumor cells and cell clusters

(2017) Masanori Hayashi et al.   Oncotarget

The Evolution and Ecology of Resistance in Cancer Therapy

(2017) Robert Gatenby et al.   Cold Spring Harbor Perspectives in Medicine

Highly personalized detection of minimal Ewing sarcoma disease burden from plasma tumor DNA

(2016) Masanori Hayashi et al.   CANCER

Darwinian Dynamics of Intratumoral Heterogeneity: Not Solely Random Mutations but Also Variable Environmental Selection Forces

(2016) M. C. Lloyd et al.   CANCER RESEARCH

Intensive Multiagent Therapy, Including Dose-Compressed Cycles of Ifosfamide/Etoposide and Vincristine/Doxorubicin/Cyclophosphamide, Irinotecan, and Radiation, in Patients With High-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group

(2016) Brenda J. Weigel et al.   JOURNAL OF CLINICAL ONCOLOGY

Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial

(2016) Neyssa M Marina et al.   LANCET ONCOLOGY

Radiomics: Images Are More than Pictures, They Are Data

(2016) Robert J. Gillies et al.   RADIOLOGY

Exploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer

(2016) Pedro M. Enriquez-Navas et al.   Science Translational Medicine

Current state of pediatric sarcoma biology and opportunities for future discovery: A report from the sarcoma translational research workshop

(2016) Pooja Hingorani et al.   Cancer Genetics

Methotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial

(2015) Stefan S. Bielack et al.   JOURNAL OF CLINICAL ONCOLOGY

Suppression of Reserve MCM Complexes Chemosensitizes to Gemcitabine and 5-Fluorouracil

(2015) V. L. Bryant et al.   MOLECULAR CANCER RESEARCH

Intermittent Hypoxia Selects for Genotypes and Phenotypes That Increase Survival, Invasion, and Therapy Resistance

(2015) Daniel Verduzco et al.   PLoS One

EURAMOS-1, an international randomised study for osteosarcoma: results from pre-randomisation treatment†

(2014) J. S. Whelan et al.   ANNALS OF ONCOLOGY

Genetics in conservation management: Revised recommendations for the 50/500 rules, Red List criteria and population viability analyses

(2014) Richard Frankham et al.   BIOLOGICAL CONSERVATION

Drastic population fluctuations explain the rapid extinction of the passenger pigeon

(2014) C.-M. Hung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary triage governs fitness in driver and passenger mutations and suggests targeting never mutations

(2014) R. A. Gatenby et al.   Nature Communications

Targeting the DNA Repair Pathway in Ewing Sarcoma

(2014) Elizabeth Stewart et al.   Cell Reports

Acidity Generated by the Tumor Microenvironment Drives Local Invasion

(2013) V. Estrella et al.   CANCER RESEARCH

Early response as assessed by anatomic imaging does not predict failure-free survival among patients with Group III rhabdomyosarcoma: A report from the Children’s Oncology Group

(2013) Abby R. Rosenberg et al.   EUROPEAN JOURNAL OF CANCER

Phase II Trial of Trastuzumab in Combination With Cytotoxic Chemotherapy for Treatment of Metastatic Osteosarcoma With Human Epidermal Growth Factor Receptor 2 Overexpression: A Report From the Children's Oncology Group

(2012) David Ebb et al.   JOURNAL OF CLINICAL ONCOLOGY

Randomized Controlled Trial of Interval-Compressed Chemotherapy for the Treatment of Localized Ewing Sarcoma: A Report From the Children's Oncology Group

(2012) Richard B. Womer et al.   JOURNAL OF CLINICAL ONCOLOGY

Children's Oncology Group's 2013 blueprint for research: Bone tumors

(2012) Richard Gorlick et al.   PEDIATRIC BLOOD & CANCER

Children's Oncology Group's 2013 blueprint for research: Soft tissue sarcomas

(2012) Douglas S. Hawkins et al.   PEDIATRIC BLOOD & CANCER

Does the cell number 109still really fit one gram of tumor tissue?

(2011) Ugo Del Monte   CELL CYCLE

Phase II evaluation of intravenous vinorelbine (Navelbine) in recurrent or refractory pediatric malignancies: A Children's Oncology Group study

(2009) John F. Kuttesch et al.   PEDIATRIC BLOOD & CANCER