Evolutionary triage governs fitness in driver and passenger mutations and suggests targeting never mutations

Coming Full Circle—From Endless Complexity to Simplicity and Back Again

(2014) Robert A. Weinberg   CELL

Antitumor activity of the ERK inhibitor SCH722984 against BRAF mutant, NRAS mutant and wild-type melanoma

(2014) Deborah JL Wong et al.   Molecular Cancer

Radiologically Defined Ecological Dynamics and Clinical Outcomes in Glioblastoma Multiforme: Preliminary Results

(2014) Mu Zhou et al.   Translational Oncology

The Evolution of Melanoma Resistance Reveals Therapeutic Opportunities

(2013) M. D. Thakur et al.   CANCER RESEARCH

Targeted therapy in melanoma

(2013) Ragini R. Kudchadkar et al.   CLINICS IN DERMATOLOGY

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

Impact of deleterious passenger mutations on cancer progression

(2013) C. D. McFarland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perspective: Finding cancer's first principles

(2012) Robert Gatenby   NATURE

Clonal evolution in cancer

(2012) Mel Greaves et al.   NATURE

Evolutionary Game Theory as a Framework for Studying Biological Invasions

(2011) Lauren M. Pintor et al.   AMERICAN NATURALIST

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Evolutionary Dynamics in Cancer Therapy

(2011) Jessica J. Cunningham et al.   MOLECULAR PHARMACEUTICS

How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine

(2010) M Gerlinger et al.   BRITISH JOURNAL OF CANCER

Gefitinib or Chemotherapy for Non–Small-Cell Lung Cancer with Mutated EGFR

(2010) Makoto Maemondo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Accumulation of driver and passenger mutations during tumor progression

(2010) I. Bozic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of Genetic Inheritance in a Family Quartet by Whole-Genome Sequencing

(2010) J. C. Roach et al.   SCIENCE

ENVIRONMENTAL DEPENDENCY OF GENE KNOCKOUTS ON PHENOTYPE MICROARRAY ANALYSIS IN ESCHERICHIA COLI

(2010) YUKAKO TOHSATO et al.   Journal of Bioinformatics and Computational Biology

Lessons from Applied Ecology: Cancer Control Using an Evolutionary Double Bind

(2009) R. A. Gatenby et al.   CANCER RESEARCH

The cancer genome

(2009) Michael R. Stratton et al.   NATURE