Impairment of carbonic anhydrase IX ectodomain cleavage reinforces tumorigenic and metastatic phenotype of cancer cells

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Status update on iRhom and ADAM17: It's still complicated

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The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion

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Apoptosis-induced ectodomain shedding of hypoxia-regulated carbonic anhydrase IX from tumor cells: a double-edged response to chemotherapy

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Prognostic value of serum carbonic anhydrase IX in testicular germ cell tumor patients

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Erratum: Thrombospondin-1 repression is mediated via distinct mechanisms in fibroblasts and epithelial cells

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Hypoxia-induced carbonic anhydrase IX as a target for cancer therapy: From biology to clinical use

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The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17

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Knock out of the BASIGIN/CD147 chaperone of lactate/H+ symporters disproves its pro-tumour action via extracellular matrix metalloproteases (MMPs) induction

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Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function

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LC–MS Based Cleavage Site Profiling of the Proteases ADAM10 and ADAM17 Using Proteome-Derived Peptide Libraries

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Suppression of carbonic anhydrase IX leads to aberrant focal adhesion and decreased invasion of tumor cells

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Carbonic anhydrase IX

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The effect of carbonic anhydrase IX on focal contacts during cell spreading and migration

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Binding of carbonic anhydrase IX to extracellular loop 4 of the NBCe1 Na+/HCO3− cotransporter enhances NBCe1-mediated HCO3− influx in the rat heart

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Carbonic anhydrase IX is a clinically significant tissue and serum biomarker associated with renal cell carcinoma

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Carbonic anhydrase IX in tumor tissue and sera of patients with primary cervical cancer

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Phosphorylation of Carbonic Anhydrase IX Controls Its Ability to Mediate Extracellular Acidification in Hypoxic Tumors

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Carbonic Anhydrase IX Interacts with Bicarbonate Transporters in Lamellipodia and Increases Cell Migration via Its Catalytic Domain

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The unfolded protein response controls induction and activation of ADAM17/TACE by severe hypoxia and ER stress

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Molecular and Cellular Mechanisms of Ectodomain Shedding

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Perspectives in mammalian IGFBP-3 biology: local vs. systemic action

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Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases

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The Role of Carbonic Anhydrase 9 in Regulating Extracellular and Intracellular pH in Three-dimensional Tumor Cell Growths

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A Disintegrin and Metalloproteinase 17 (ADAM17) Mediates Inflammation-induced Shedding of Syndecan-1 and -4 by Lung Epithelial Cells

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Protons make tumor cells move like clockwork

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Cancer-associated, hypoxia-inducible carbonic anhydrase IX facilitates CO2diffusion

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Molecular mechanisms of carbonic anhydrase IX-mediated pH regulation under hypoxia

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Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH

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Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression

(2008) Jennifer S. Fang et al.   SEMINARS IN CANCER BIOLOGY