Carbonic anhydrase IX

Suppression of carbonic anhydrase IX leads to aberrant focal adhesion and decreased invasion of tumor cells

(2013) PETER RADVAK et al.   ONCOLOGY REPORTS

Binding of carbonic anhydrase IX to extracellular loop 4 of the NBCe1 Na+/HCO3− cotransporter enhances NBCe1-mediated HCO3− influx in the rat heart

(2012) Alejandro Orlowski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Regulation of intracellular pH in cancer cell lines under normoxia and hypoxia

(2012) Alzbeta Hulikova et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Phosphorylation of Carbonic Anhydrase IX Controls Its Ability to Mediate Extracellular Acidification in Hypoxic Tumors

(2011) P. Ditte et al.   CANCER RESEARCH

Dual Role of CO2/HCO3−Buffer in the Regulation of Intracellular pH of Three-dimensional Tumor Growths

(2011) Alzbeta Hulikova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Carbonic Anhydrase IX Interacts with Bicarbonate Transporters in Lamellipodia and Increases Cell Migration via Its Catalytic Domain

(2011) Eliska Svastova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The unfolded protein response controls induction and activation of ADAM17/TACE by severe hypoxia and ER stress

(2011) T Rzymski et al.   ONCOGENE

Protein Kinase A Activity and Anchoring Are Required for Ovarian Cancer Cell Migration and Invasion

(2011) Andrew J. McKenzie et al.   PLoS One

Intracellular pH gradients in migrating cells

(2010) Christine Martin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

WAVE2 Forms a Complex with PKA and Is Involved in PKA Enhancement of Membrane Protrusions

(2010) Hiroshi Yamashita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

pH control mechanisms of tumor survival and growth

(2010) Scott K. Parks et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mechanisms of Motility in Metastasizing Cells

(2010) Mahmut Yilmaz et al.   MOLECULAR CANCER RESEARCH

Bicarbonate Increases Tumor pH and Inhibits Spontaneous Metastases

(2009) I. F. Robey et al.   CANCER RESEARCH

The role of hypoxia and acidosis in promoting metastasis and resistance to chemotherapy

(2009) Katie DeClerck   Frontiers in Bioscience-Landmark

The Role of Carbonic Anhydrase 9 in Regulating Extracellular and Intracellular pH in Three-dimensional Tumor Cell Growths

(2009) Pawel Swietach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protons make tumor cells move like clockwork

(2009) Christian Stock et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Molecular mechanisms of carbonic anhydrase IX-mediated pH regulation under hypoxia

(2008) Silvia Pastorekova et al.   BJU INTERNATIONAL

Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH

(2008) J. Chiche et al.   CANCER RESEARCH

Acid treatment of melanoma cells selects for invasive phenotypes

(2008) Raymond E. Moellering et al.   CLINICAL & EXPERIMENTAL METASTASIS

Spatial Distribution of Protein Kinase A Activity during Cell Migration Is Mediated by A-kinase Anchoring Protein AKAP Lbc

(2008) Adriana A. Paulucci-Holthauzen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin-mediated Protein Kinase A Activation at the Leading Edge of Migrating Cells

(2008) Chinten J. Lim et al.   MOLECULAR BIOLOGY OF THE CELL

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY

Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression

(2008) Jennifer S. Fang et al.   SEMINARS IN CANCER BIOLOGY