Understanding heterogeneity of fetal hemoglobin induction through comparative analysis of F and A erythroblasts

Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation

(2020) Anindita Basak et al.   NATURE GENETICS

Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis

(2019) Falak Sher et al.   NATURE GENETICS

Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells

(2018) Yankai Zhang et al.   BLOOD

14q32 and let-7 microRNAs regulate transcriptional networks in fetal and adult human erythroblasts

(2018) Samuel Lessard et al.   HUMAN MOLECULAR GENETICS

Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells

(2018) Jeremy D. Grevet et al.   SCIENCE

Fetal γ-globin genes are regulated by the BGLT3 long non-coding RNA locus

(2018) Maria Soledad Ivaldi et al.   BLOOD

A Transcriptome-wide Translational Program Defined by LIN28B Expression Level

(2018) Frederick E. Tan et al.   MOLECULAR CELL

Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element

(2017) Peng Huang et al.   GENES & DEVELOPMENT

LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency

(2016) Jin Zhang et al.   Cell Stem Cell

Enhancer Regulation of Transcriptional Bursting Parameters Revealed by Forced Chromatin Looping

(2016) Caroline R. Bartman et al.   MOLECULAR CELL

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin

(2016) T. Masuda et al.   SCIENCE

Comprehensive Proteomic Analysis of Human Erythropoiesis

(2016) Emilie-Fleur Gautier et al.   Cell Reports

LIN28Boverexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia

(2015) Hetty H. Helsmoortel et al.   BLOOD

Pomalidomide reverses  -globin silencing through the transcriptional reprogramming of adult hematopoietic progenitors

(2015) B. M. Dulmovits et al.   BLOOD

Lin28b promotes fetal B lymphopoiesis through the transcription factor Arid3a

(2015) Yan Zhou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Comparison of DNA methylation profiles in human fetal and adult red blood cell progenitors

(2015) Samuel Lessard et al.   Genome Medicine

Variation in Gamma-Globin Expression before and after Induction with Hydroxyurea Associated with BCL11A, KLF1 and TAL1

(2015) Amanda J. Grieco et al.   PLoS One

Global transcriptome analyses of human and murine terminal erythroid differentiation

(2014) X. An et al.   BLOOD

MARIS: Method for Analyzing RNA following Intracellular Sorting

(2014) Siniša Hrvatin et al.   PLoS One

Whole Exome Sequencing Identifies Novel Genes for Fetal Hemoglobin Response to Hydroxyurea in Children with Sickle Cell Anemia

(2014) Vivien A. Sheehan et al.   PLoS One

LIN28B-mediated expression of fetal hemoglobin and production of fetal-like erythrocytes from adult human erythroblasts ex vivo

(2013) Y. T. Lee et al.   BLOOD

Fetal hemoglobin in sickle cell anemia: a glass half full?

(2013) M. H. Steinberg et al.   BLOOD

Establishment of Immortalized Human Erythroid Progenitor Cell Lines Able to Produce Enucleated Red Blood Cells

(2013) Ryo Kurita et al.   PLoS One

Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A

(2013) J. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Erythroid Enhancer of BCL11A Subject to Genetic Variation Determines Fetal Hemoglobin Level

(2013) D. E. Bauer et al.   SCIENCE

Hydroxycarbamide alters erythroid gene expression in children with sickle cell anaemia

(2012) Jonathan M. Flanagan et al.   BRITISH JOURNAL OF HAEMATOLOGY

Combinatorial Assembly of Developmental Stage-Specific Enhancers Controls Gene Expression Programs during Human Erythropoiesis

(2012) Jian Xu et al.   DEVELOPMENTAL CELL

Lin28b Reprograms Adult Bone Marrow Hematopoietic Progenitors to Mediate Fetal-Like Lymphopoiesis

(2012) Joan Yuan et al.   SCIENCE

Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice

(2011) S. E. Meiler et al.   BLOOD

A Functional Element Necessary for Fetal Hemoglobin Silencing

(2011) Vijay G. Sankaran et al.   NEW ENGLAND JOURNAL OF MEDICINE

Developmental and species-divergent globin switching are driven by BCL11A

(2009) Vijay G. Sankaran et al.   NATURE

Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells

(2008) Laure A. Moutouh-de Parseval et al.   JOURNAL OF CLINICAL INVESTIGATION

Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA

(2008) Inha Heo et al.   MOLECULAR CELL