Variation in Gamma-Globin Expression before and after Induction with Hydroxyurea Associated with BCL11A, KLF1 and TAL1

The hematopoietic regulator TAL1 is required for chromatin looping between the β-globin LCR and human γ-globin genes to activate transcription

(2014) Won Ju Yun et al.   NUCLEIC ACIDS RESEARCH

Systematic Review: Hydroxyurea for the Treatment of Adults with Sickle Cell Disease

(2013) Sophie Lanzkron et al.   ANNALS OF INTERNAL MEDICINE

Clinical experience with fetal hemoglobin induction therapy in patients with  -thalassemia

(2013) K. M. Musallam et al.   BLOOD

Quantification ofHBGmRNA in primary erythroid cultures: prediction of the response to hydroxyurea in sickle cell and beta-thalassemia

(2013) Alice Pecoraro et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Disruption of the Hbs1l-Myb Locus Causes Hereditary Persistence of Fetal Hemoglobin in a Mouse Model

(2013) M. Suzuki et al.   MOLECULAR AND CELLULAR BIOLOGY

Emerging science of hydroxyurea therapy for pediatric sickle cell disease

(2013) Nancy S. Green et al.   PEDIATRIC RESEARCH

Candidate Sequence Variants and Fetal Hemoglobin in Children with Sickle Cell Disease Treated with Hydroxyurea

(2013) Nancy S. Green et al.   PLoS One

An Erythroid Enhancer of BCL11A Subject to Genetic Variation Determines Fetal Hemoglobin Level

(2013) D. E. Bauer et al.   SCIENCE

Hydroxycarbamide alters erythroid gene expression in children with sickle cell anaemia

(2012) Jonathan M. Flanagan et al.   BRITISH JOURNAL OF HAEMATOLOGY

Hydroxyurea responsiveness in  -thalassemic patients is determined by the stress response adaptation of erythroid progenitors and their differentiation propensity

(2012) F. Pourfarzad et al.   HAEMATOLOGICA

Effect of AGM and Fetal Liver-Derived Stromal Cell Lines on Globin Expression in Adult Baboon (P. anubis) Bone Marrow-Derived Erythroid Progenitors

(2012) Donald Lavelle et al.   PLoS One

Pharmacokinetics, pharmacodynamics, and pharmacogenetics of hydroxyurea treatment for children with sickle cell anemia

(2011) R. E. Ware et al.   BLOOD

A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression

(2011) J. J. Farrell et al.   BLOOD

Epigenetic and molecular profiles of erythroid cells after hydroxyurea treatment in sickle cell anemia

(2011) A. L. Walker et al.   BLOOD

Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG)

(2011) Winfred C Wang et al.   LANCET

c-myb supports erythropoiesis through the transactivation of KLF1 and LMO2 expression

(2010) E. Bianchi et al.   BLOOD

The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation

(2010) E. Soler et al.   GENES & DEVELOPMENT

Transcriptional silencing of  -globin by BCL11A involves long-range interactions and cooperation with SOX6

(2010) J. Xu et al.   GENES & DEVELOPMENT

A requirement for Lim domain binding protein 1 in erythropoiesis

(2010) LiQi Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification

(2009) Athanasia Spandidos et al.   NUCLEIC ACIDS RESEARCH

BCL11A is a major HbF quantitative trait locus in three different populations with β-hemoglobinopathies

(2008) Amanda E. Sedgewick et al.   BLOOD CELLS MOLECULES AND DISEASES

DNA polymorphisms at the BCL11A, HBS1L-MYB, and  -globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

(2008) G. Lettre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific RepressorBCL11A

(2008) Vijay G. Sankaran et al.   SCIENCE