Synergism between SLC6A14 blockade and gemcitabine in pancreactic cancer: a 1H-NMR-based metabolomic study in pancreatic cancer cells

The role of transporters in cancer redox homeostasis and cross-talk with nanomedicines

(2020) Longfa Kou et al.   Asian Journal of Pharmaceutical Sciences

Bitter melon juice-intake modulates glucose metabolism and lactate efflux in tumors in its efficacy against pancreatic cancer

(2019) Deepanshi Dhar et al.   CARCINOGENESIS

1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma

(2019) Giuseppina D’Alessandro et al.   Cell Communication and Signaling

Lactate/GPR81 signaling and proton motive force in cancer: Role in angiogenesis, immune escape, nutrition, and Warburg phenomenon

(2019) Timothy P. Brown et al.   PHARMACOLOGY & THERAPEUTICS

The role of ASCT2 in cancer: A review

(2018) Yang Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Metabolic switching in the hypoglycemic and antitumor effects of metformin on high glucose induced HepG2 cells

(2018) Yan Lv et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

1H Nuclear Magnetic Resonance Based Metabolomics Approach Reveals the Metabolic Mechanism of (−)-5-Hydroxy-equol against Hepatocellular Carcinoma Cells in Vitro

(2018) Li Gao et al.   JOURNAL OF PROTEOME RESEARCH

Keep Quiet and Stay in Line! Smart Polymers to Keep an Eye on Pancreatic Tumors

(2018) Pierre Cordelier   MOLECULAR THERAPY

Characteristic Metabolic Alterations Identified in Primary Neurons Under High Glucose Exposure

(2018) Liangcai Zhao et al.   Frontiers in Cellular Neuroscience

Metabolomic Analysis Identifies Lactate as One Important Pathogenic Factor in Diabetes-associated Cognitive Decline Rats

(2018) Liangcai Zhao et al.   MOLECULAR & CELLULAR PROTEOMICS

Amino acid transporters revisited: New views in health and disease

(2018) Palanivel Kandasamy et al.   TRENDS IN BIOCHEMICAL SCIENCES

Targeting indoleamine-2,3-dioxygenase in cancer: Scientific rationale and clinical evidence

(2018) Biagio Ricciuti et al.   PHARMACOLOGY & THERAPEUTICS

Time-Dependent Lactate Production and Amino Acid Utilization in Cultured Astrocytes Under High Glucose Exposure

(2017) Dan Wang et al.   MOLECULAR NEUROBIOLOGY

Efficient Codelivery of Paclitaxel and Curcumin by Novel Bottlebrush Copolymer-based Micelles

(2017) Qing Yao et al.   MOLECULAR PHARMACEUTICS

SLC transporters as a novel class of tumour suppressors: identity, function and molecular mechanisms

(2016) Y. D. Bhutia et al.   BIOCHEMICAL JOURNAL

Glutamine transporters in mammalian cells and their functions in physiology and cancer

(2016) Yangzom D. Bhutia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer

(2016) V Coothankandaswamy et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pancreatic cancer

(2016) Terumi Kamisawa et al.   LANCET

IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance

(2016) David H. Munn et al.   TRENDS IN IMMUNOLOGY

Deletion of the amino acid transporter Slc6a14 suppresses tumour growth in spontaneous mouse models of breast cancer

(2015) Ellappan Babu et al.   BIOCHEMICAL JOURNAL

Amino Acid Transporters in Cancer and Their Relevance to "Glutamine Addiction": Novel Targets for the Design of a New Class of Anticancer Drugs

(2015) Y. D. Bhutia et al.   CANCER RESEARCH

Metabolomics in cell culture—A strategy to study crucial metabolic pathways in cancer development and the response to treatment

(2014) Anna Halama   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The amino acid transporter SLC6A14 in cancer and its potential use in chemotherapy

(2014) Yangzom D. Bhutia et al.   Asian Journal of Pharmaceutical Sciences

Proteomics and metabolomics in cancer drug development

(2013) Angelo D’Alessandro et al.   Expert Review of Proteomics

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

(2013) Jaekyoung Son et al.   NATURE

Cell Metabolomics

(2013) Aihua Zhang et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Metabolic reprogramming in cancer: Unraveling the role of glutamine in tumorigenesis

(2012) Dania Daye et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Developments in metastatic pancreatic cancer: Is gemcitabine still the standard?

(2012) Jie-Er Ying   WORLD JOURNAL OF GASTROENTEROLOGY

SLC6A14 (ATB0,+) Protein, a Highly Concentrative and Broad Specific Amino Acid Transporter, Is a Novel and Effective Drug Target for Treatment of Estrogen Receptor-positive Breast Cancer

(2011) Senthil Karunakaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Randomized Phase III Trial of Gemcitabine Plus Cisplatin Compared With Single-Agent Gemcitabine As First-Line Treatment of Patients With Advanced Pancreatic Cancer: The GIP-1 Study

(2010) Giuseppe Colucci et al.   JOURNAL OF CLINICAL ONCOLOGY

Fermentanomics: Monitoring Mammalian Cell Cultures with NMR Spectroscopy

(2010) Scott A. Bradley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

icoshift: A versatile tool for the rapid alignment of 1D NMR spectra

(2009) F. Savorani et al.   JOURNAL OF MAGNETIC RESONANCE

Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy

(2008) Senthil Karunakaran et al.   BIOCHEMICAL JOURNAL

A direct cell quenching method for cell-culture based metabolomics

(2008) Quincy Teng et al.   Metabolomics

Nutrient transporters in cancer: Relevance to Warburg hypothesis and beyond

(2008) Vadivel Ganapathy et al.   PHARMACOLOGY & THERAPEUTICS