Induction of DNA damage and erroneous repair can explain genomic instability caused by endosulfan

Microhomology-mediated end joining is the principal mediator of double-strand break repair during mitochondrial DNA lesions

(2016) Satish Kumar Tadi et al.   MOLECULAR BIOLOGY OF THE CELL

Interactive effects of ultraviolet-B radiation and pesticide exposure on DNA photo-adduct accumulation and expression of DNA damage and repair genes in Xenopus laevis embryos

(2015) Shuangying Yu et al.   AQUATIC TOXICOLOGY

DNA Double-Strand Break Repair Inhibitors as Cancer Therapeutics

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Evaluation of genotoxicity using automated detection of γH2AX in metabolically competent HepaRG cells

(2015) Nicolas Quesnot et al.   MUTAGENESIS

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

(2015) Raphael Ceccaldi et al.   NATURE

Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination

(2015) Pedro A. Mateos-Gomez et al.   NATURE

PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair

(2015) T. Ochi et al.   SCIENCE

Endosulfan induces male infertility

(2015) R Sebastian et al.   Cell Death & Disease

Homology and enzymatic requirements of microhomology-dependent alternative end joining

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Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway

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Antibiotics induce redox-related physiological alterations as part of their lethality

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Modernizing the Nonhomologous End-Joining Repertoire: Alternative and Classical NHEJ Share the Stage

(2013) Ludovic Deriano et al.   Annual Review of Genetics

Evaluating Pesticide Degradation in the Environment: Blind Spots and Emerging Opportunities

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53BP1: pro choice in DNA repair

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A Hormone-DNA Repair Circuit Governs the Response to Genotoxic Insult

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Androgen Receptor Signaling Regulates DNA Repair in Prostate Cancers

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An Inhibitor of Nonhomologous End-Joining Abrogates Double-Strand Break Repair and Impedes Cancer Progression

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DNA damage and oxidative stress induced by endosulfan exposure in zebrafish (Danio rerio)

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Organochlorine pesticide, endosulfan induced cellular and organismal response in Drosophila melanogaster

(2012) Anurag Sharma et al.   JOURNAL OF HAZARDOUS MATERIALS

Time-Dependent Predominance of Nonhomologous DNA End-Joining Pathways during Embryonic Development in Mice

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Double-Strand Break End Resection and Repair Pathway Choice

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How does DNA break during chromosomal translocations?

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DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation

(2011) Deniz Simsek et al.   PLoS Genetics

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

Efficiency of nonhomologous DNA end joining varies among somatic tissues, despite similarity in mechanism

(2010) Sheetal Sharma et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ameliorating effect of N-acetylcysteine and curcumin on pesticide-induced oxidative DNA damage in human peripheral blood mononuclear cells

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Anti-apoptotic Protein BCL2 Down-regulates DNA End Joining in Cancer Cells

(2010) Tadi Satish Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-androgenic endocrine disrupting activities of chlorpyrifos and piperophos

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H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes

(2010) Beth A. Helmink et al.   NATURE

Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70

(2010) C. Boboila et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An assessment of the developmental, reproductive, and neurotoxicity of endosulfan

(2009) Marilyn H. Silva et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Effect of Occupational Exposure to Multiple Pesticides on Translocation Yield and Chromosomal Aberrations in Lymphocytes of Plant Workers

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Agricultural pesticide exposure and the molecular connection to lymphomagenesis

(2009) Julie Agopian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Novel derivatives of spirohydantoin induce growth inhibition followed by apoptosis in leukemia cells

(2008) C.V. Kavitha et al.   BIOCHEMICAL PHARMACOLOGY

Lymphocyte-Specific Compensation for XLF/Cernunnos End-Joining Functions in V(D)J Recombination

(2008) Gang Li et al.   MOLECULAR CELL