Potential and Challenges of Improving Photosynthesis in Algae

Transcriptional regulation of microalgae for concurrent lipid overproduction and secretion

(2019) Da-Wei Li et al.   Science Advances

Structural basis for blue-green light harvesting and energy dissipation in diatoms

(2019) Wenda Wang et al.   SCIENCE

Multi-omics analysis reveals distinct mechanism of oleaginousness in the emerging model alga Chromochloris zofingiensis

(2019) Jin Liu et al.   PLANT JOURNAL

LHC-like proteins involved in stress responses and biogenesis/repair of the photosynthetic apparatus

(2019) Jean-David Rochaix et al.   BIOCHEMICAL JOURNAL

A homolog of Arabidopsis SDP1 lipase in Nannochloropsis is involved in degradation of de novo-synthesized triacylglycerols in the endoplasmic reticulum

(2019) Takashi Nobusawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Microsecond and millisecond dynamics in the photosynthetic protein LHCSR1 observed by single-molecule correlation spectroscopy

(2019) Toru Kondo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chlamydomonas cell cycle mutant crcdc5 over-accumulates starch and oil

(2019) Ismael Torres-Romero et al.   BIOCHIMIE

Combined resistance to oxidative stress and reduced antenna size enhance light-to-biomass conversion efficiency in Chlorella vulgaris cultures

(2019) Luca Dall’Osto et al.   Biotechnology for Biofuels

Regulation of photoprotection gene expression in Chlamydomonas by a putative E3 ubiquitin ligase complex and a homolog of CONSTANS

(2019) Stéphane T. Gabilly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a C2S2M2N2-type PSII–LHCII supercomplex from the green alga Chlamydomonas reinhardtii

(2019) Liangliang Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Myb‐like transcription factor phosphorus starvation response (PtPSR) controls conditional P acquisition and remodelling in marine microalgae

(2019) Amit Kumar Sharma et al.   NEW PHYTOLOGIST

Characterization and engineering of a dual-function diacylglycerol acyltransferase in the oleaginous marine diatom Phaeodactylum tricornutum

(2018) Yulin Cui et al.   Biotechnology for Biofuels

Overexpression of Malonyl-CoA: ACP Transacylase in Schizochytrium sp. to Improve Polyunsaturated Fatty Acid Production

(2018) Zhipeng Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Lipid accumulation during nitrogen and sulfur starvation in Chlamydomonas reinhardtii overexpressing a transcription factor

(2018) Carlos Joel Salas-Montantes et al.   JOURNAL OF APPLIED PHYCOLOGY

De novo transcriptomic analysis of the oleaginous alga Botryococcus braunii AC768 (Chlorophyta)

(2018) Xiaolin Zhang et al.   JOURNAL OF APPLIED PHYCOLOGY

Constitutive and Chloroplast Targeted Expression of Acetyl-CoA Carboxylase in Oleaginous Microalgae Elevates Fatty Acid Biosynthesis

(2018) Da-Wei Li et al.   MARINE BIOTECHNOLOGY

Phototrophic production of heterologous diterpenoids and a hydroxy-functionalized derivative from Chlamydomonas reinhardtii

(2018) Kyle J. Lauersen et al.   METABOLIC ENGINEERING

Tailored carbon partitioning for phototrophic production of ( E )-α-bisabolene from the green microalga Chlamydomonas reinhardtii

(2018) Julian Wichmann et al.   METABOLIC ENGINEERING

Engineered cyanobacteria with enhanced growth show increased ethanol production and higher biofuel to biomass ratio

(2018) Feiyan Liang et al.   METABOLIC ENGINEERING

High-efficiency promoter-driven coordinated regulation of multiple metabolic nodes elevates lipid accumulation in the model microalga Phaeodactylum tricornutum

(2018) Li-Gong Zou et al.   Microbial Cell Factories

Intron-containing algal transgenes mediate efficient recombinant gene expression in the green microalga Chlamydomonas reinhardtii

(2018) Thomas Baier et al.   NUCLEIC ACIDS RESEARCH

Engineering the unicellular alga Phaeodactylum tricornutum for high-value plant triterpenoid production

(2018) Sarah D'Adamo et al.   PLANT BIOTECHNOLOGY JOURNAL

Hunting the main player enabling Chlamydomonas reinhardtii growth under fluctuating light

(2018) Martina Jokel et al.   PLANT JOURNAL

Over-accumulation of astaxanthin in Haematococcus pluvialis through chloroplast genetic engineering

(2018) Janeth I. Galarza et al.   Algal Research-Biomass Biofuels and Bioproducts

Structure of a PSI–LHCI–cyt b6f supercomplex in Chlamydomonas reinhardtii promoting cyclic electron flow under anaerobic conditions

(2018) Janina Steinbeck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhancement of lipid accumulation in microalgae by metabolic engineering

(2018) Xiao-Man Sun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The small RbcS-like domains of the β-carboxysome structural protein, CcmM, bind RubisCO at a site distinct from that binding the RbcS subunit

(2018) Patrick Ryan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biomass from microalgae: the potential of domestication towards sustainable biofactories

(2018) Manuel Benedetti et al.   Microbial Cell Factories

Engineering cyanobacteria for production of terpenoids

(2018) Po-Cheng Lin et al.   PLANTA

Eukaryotic microalgae as hosts for light-driven heterologous isoprenoid production

(2018) Kyle J. Lauersen   PLANTA

The phase separation underlying the pyrenoid-based microalgal Rubisco supercharger

(2018) Tobias Wunder et al.   Nature Communications

Effect of overexpression of LPAAT and GPD1 on lipid synthesis and composition in green microalga Chlamydomonas reinhardtii

(2017) Chaogang Wang et al.   JOURNAL OF APPLIED PHYCOLOGY

Genetic engineering of medium-chain-length fatty acid synthesis in Dunaliella tertiolecta for improved biodiesel production

(2017) Huixin Lin et al.   JOURNAL OF APPLIED PHYCOLOGY

Expression of the heterologous Dunaliella tertiolecta fatty acyl-ACP thioesterase leads to increased lipid production in Chlamydomonas reinhardtii

(2017) Kenneth Wei Min Tan et al.   JOURNAL OF BIOTECHNOLOGY

Deletion of the chloroplast LTD protein impedes LHCI import and PSI–LHCI assembly in Chlamydomonas reinhardtii

(2017) Jooyeon Jeong et al.   JOURNAL OF EXPERIMENTAL BOTANY

Glucose-6-phosphate dehydrogenase as a target for highly efficient fatty acid biosynthesis in microalgae by enhancing NADPH supply

(2017) Jiao Xue et al.   METABOLIC ENGINEERING

Functional Accumulation of Antenna Proteins in Chlorophyll b -Less Mutants of Chlamydomonas reinhardtii

(2017) Sandrine Bujaldon et al.   Molecular Plant

Lipid production in Nannochloropsis gaditana is doubled by decreasing expression of a single transcriptional regulator

(2017) Imad Ajjawi et al.   NATURE BIOTECHNOLOGY

Single-molecule spectroscopy of LHCSR1 protein dynamics identifies two distinct states responsible for multi-timescale photosynthetic photoprotection

(2017) Toru Kondo et al.   Nature Chemistry

Structure and assembly mechanism of plant C2S2M2-type PSII-LHCII supercomplex

(2017) Xiaodong Su et al.   SCIENCE

Metabolic engineering of the pentose phosphate pathway for enhanced limonene production in the cyanobacterium Synechocysti s sp. PCC 6803

(2017) Po-Cheng Lin et al.   Scientific Reports

Bioenergy application of Dunaliella salina SA 134 grown at various salinity levels for lipid production

(2017) Rajper Aftab Ahmed et al.   Scientific Reports

Enhancing photosynthetic biomass productivity of industrial oleaginous microalgae by overexpression of RuBisCO activase

(2017) Li Wei et al.   Algal Research-Biomass Biofuels and Bioproducts

Microalgae, old sustainable food and fashion nutraceuticals

(2017) José L. García et al.   Microbial Biotechnology

Electron transfer between carotenoid and chlorophyll contributes to quenching in the LHCSR1 protein from Physcomitrella patens

(2016) Alberta Pinnola et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Molecular characterization of a glycerol-3-phosphate acyltransferase reveals key features essential for triacylglycerol production in Phaeodactylum tricornutum

(2016) Ying-Fang Niu et al.   Biotechnology for Biofuels

Engineering the methylerythritol phosphate pathway in cyanobacteria for photosynthetic isoprene production from CO2

(2016) Xiang Gao et al.   Energy & Environmental Science

Identification of pH-sensing Sites in the Light Harvesting Complex Stress-related 3 Protein Essential for Triggering Non-photochemical Quenching inChlamydomonas reinhardtii

(2016) Matteo Ballottari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A type 2 diacylglycerol acyltransferase accelerates the triacylglycerol biosynthesis in heterokont oleaginous microalga Nannochloropsis oceanica

(2016) Da-Wei Li et al.   JOURNAL OF BIOTECHNOLOGY

Effects of overexpressing photosynthetic carbon flux control enzymes in the cyanobacterium Synechocystis PCC 6803

(2016) Feiyan Liang et al.   METABOLIC ENGINEERING

Efficient phototrophic production of a high-value sesquiterpenoid from the eukaryotic microalga Chlamydomonas reinhardtii

(2016) Kyle J. Lauersen et al.   METABOLIC ENGINEERING

The mechanisms whereby the green algaChlorella ohadii, isolated from desert soil crust, exhibits unparalleled photodamage resistance

(2016) Haim Treves et al.   NEW PHYTOLOGIST

Identification of aChlamydomonasplastidial 2-lysophosphatidic acid acyltransferase and its use to engineer microalgae with increased oil content

(2016) Yasuyo Yamaoka et al.   PLANT BIOTECHNOLOGY JOURNAL

Activation of the Stt7/STN7 Kinase through Dynamic Interactions with the Cytochromeb6fComplex

(2016) Alexey Shapiguzov et al.   PLANT PHYSIOLOGY

Enhanced limonene production in cyanobacteria reveals photosynthesis limitations

(2016) Xin Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improving photosynthesis and crop productivity by accelerating recovery from photoprotection

(2016) Johannes Kromdijk et al.   SCIENCE

DNA-free two-gene knockout in Chlamydomonas reinhardtii via CRISPR-Cas9 ribonucleoproteins

(2016) Kwangryul Baek et al.   Scientific Reports

Knockdown of phosphoenolpyruvate carboxykinase increases carbon flux to lipid synthesis in Phaeodactylum tricornutum

(2016) Juan Yang et al.   Algal Research-Biomass Biofuels and Bioproducts

Astaxanthin-Producing Green Microalga Haematococcus pluvialis: From Single Cell to High Value Commercial Products

(2016) Md. Mahfuzur R. Shah et al.   Frontiers in Plant Science

Biogenesis of light harvesting proteins

(2015) Luca Dall'Osto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Effects of overexpression of a bHLH transcription factor on biomass and lipid production in Nannochloropsis salina

(2015) Nam Kyu Kang et al.   Biotechnology for Biofuels

Generation of random mutants to improve light-use efficiency of Nannochloropsis gaditana cultures for biofuel production

(2015) Giorgio Perin et al.   Biotechnology for Biofuels

Fast forward genetics to identify mutations causing a high light tolerant phenotype in Chlamydomonas reinhardtii by whole-genome-sequencing

(2015) Lisa Schierenbeck et al.   BMC GENOMICS

Limitations in the biosynthesis of fucoxanthin as targets for genetic engineering in Phaeodactylum tricornutum

(2015) Ulrike Eilers et al.   JOURNAL OF APPLIED PHYCOLOGY

Regulation of astaxanthin and its intermediates through cloning and genetic transformation of β-carotene ketolase in Haematococcus pluvialis

(2015) S. Kathiresan et al.   JOURNAL OF BIOTECHNOLOGY

Non-photochemical quenching and xanthophyll cycle activities in six green algal species suggest mechanistic differences in the process of excess energy dissipation

(2015) Theresa Quaas et al.   JOURNAL OF PLANT PHYSIOLOGY

Genetic improvement of the microalga Phaeodactylum tricornutum for boosting neutral lipid accumulation

(2015) Jiao Xue et al.   METABOLIC ENGINEERING

Crystal structures of the PsbS protein essential for photoprotection in plants

(2015) Minrui Fan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structures of the PsbS protein essential for photoprotection in plants

(2015) Minrui Fan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Metabolic engineering toward enhanced LC-PUFA biosynthesis in Nannochloropsis oceanica : Overexpression of endogenous Δ12 desaturase driven by stress-inducible promoter leads to enhanced deposition of polyunsaturated fatty acids in TAG

(2015) Yuval Kaye et al.   Algal Research-Biomass Biofuels and Bioproducts

Domestication of the green alga Chlorella sorokiniana: reduction of antenna size improves light-use efficiency in a photobioreactor

(2014) Stefano Cazzaniga et al.   Biotechnology for Biofuels

Chlorella for protein and biofuels: from strain selection to outdoor cultivation in a Green Wall Panel photobioreactor

(2014) Alessia Guccione et al.   Biotechnology for Biofuels

Delta 5 Fatty Acid Desaturase Upregulates the Synthesis of Polyunsaturated Fatty Acids in the Marine Diatom Phaeodactylum tricornutum

(2014) Kun-Tao Peng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Over-expression of Dof-type transcription factor increases lipid production in Chlamydomonas reinhardtii

(2014) Alejandro Ibáñez-Salazar et al.   JOURNAL OF BIOTECHNOLOGY

Antisense knockdown of pyruvate dehydrogenase kinase promotes the neutral lipid accumulation in the diatom Phaeodactylum tricornutum

(2014) Yu-Han Ma et al.   Microbial Cell Factories

Light-Harvesting Complex Protein LHCBM9 Is Critical for Photosystem II Activity and Hydrogen Production in Chlamydomonas reinhardtii

(2014) S. Grewe et al.   PLANT CELL

Systems Analysis of the Response of Photosynthesis, Metabolism, and Growth to an Increase in Irradiance in the Photosynthetic Model Organism Chlamydomonas reinhardtii

(2014) T. Mettler et al.   PLANT CELL

Rubisco mutants of Chlamydomonas reinhardtii enhance photosynthetic hydrogen production

(2013) T. S. Pinto et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Light-harvesting complex II (LHCII) and its supramolecular organization in Chlamydomonas reinhardtii

(2013) Bartlomiej Drop et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Characterization of the photosynthetic apparatus of the Eustigmatophycean Nannochloropsis gaditana: Evidence of convergent evolution in the supramolecular organization of photosystem I

(2013) Stefania Basso et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The chloroplast signal recognition particle (CpSRP) pathway as a tool to minimize chlorophyll antenna size and maximize photosynthetic productivity

(2013) Henning Kirst et al.   BIOTECHNOLOGY ADVANCES

Recombinant expression and functional analysis of a Chlamydomonas reinhardtii bacterial-type phosphoenolpyruvate carboxylase gene fragment

(2013) Qi-Lin Tian et al.   BIOTECHNOLOGY LETTERS

The Response of Nannochloropsis gaditana to Nitrogen Starvation Includes De Novo Biosynthesis of Triacylglycerols, a Decrease of Chloroplast Galactolipids, and Reorganization of the Photosynthetic Apparatus

(2013) Diana Simionato et al.   EUKARYOTIC CELL

A newly isolatedChlorellasp. from desert sand crusts exhibits a unique resistance to excess light intensity

(2013) Haim Treves et al.   FEMS MICROBIOLOGY ECOLOGY

Metabolic engineering of Phaeodactylum tricornutum for the enhanced accumulation of omega-3 long chain polyunsaturated fatty acids

(2013) Mary L. Hamilton et al.   METABOLIC ENGINEERING

The Arabidopsis nox Mutant Lacking Carotene Hydroxylase Activity Reveals a Critical Role for Xanthophylls in Photosystem I Biogenesis

(2013) L. Dall'Osto et al.   PLANT CELL

A Dual Strategy to Cope with High Light in Chlamydomonas reinhardtii

(2013) G. Allorent et al.   PLANT CELL

Advancing oleaginous microorganisms to produce lipid via metabolic engineering technology

(2013) Ming-Hua Liang et al.   PROGRESS IN LIPID RESEARCH

Overexpression of acetyl-CoA synthetase increased the biomass and fatty acid proportion in microalga Schizochytrium

(2012) Jinfei Yan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Extraction of oil from microalgae for biodiesel production: A review

(2012) Ronald Halim et al.   BIOTECHNOLOGY ADVANCES

A Cytochrome b 5 -Containing Plastid-Located Fatty Acid Desaturase from Chlamydomonas reinhardtii

(2012) Simone Zäuner et al.   EUKARYOTIC CELL

LHCBM1 and LHCBM2/7 Polypeptides, Components of Major LHCII Complex, Have Distinct Functional Roles in Photosynthetic Antenna System ofChlamydomonas reinhardtii

(2012) Paola Ferrante et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HOW MANY SPECIES OF ALGAE ARE THERE?

(2012) Michael D. Guiry   JOURNAL OF PHYCOLOGY

Role of Xanthophylls in Light Harvesting in Green Plants: A Spectroscopic Investigation of Mutant LHCII and Lhcb Pigment–Protein Complexes

(2012) Marcel Fuciman et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Efficient Heterologous Transformation of Chlamydomonas reinhardtii npq2 Mutant with the Zeaxanthin Epoxidase Gene Isolated and Characterized from Chlorella zofingiensis

(2012) Inmaculada Couso et al.   Marine Drugs

Exploiting diversity and synthetic biology for the production of algal biofuels

(2012) D. Ryan Georgianna et al.   NATURE

Modulation of the light-harvesting chlorophyll antenna size in Chlamydomonas reinhardtii by TLA1 gene over-expression and RNA interference

(2012) M. Mitra et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Expression of theChlamydomonas reinhardtii Sedoheptulose-1,7-bisphosphataseinDunaliella bardawilleads to enhanced photosynthesis and increased glycerol production

(2012) Lei Fang et al.   PLANT BIOTECHNOLOGY JOURNAL

SINGLET OXYGEN RESISTANT 1 links reactive electrophile signaling to singlet oxygen acclimation in Chlamydomonas reinhardtii

(2012) B. B. Fischer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimization of photosynthetic light energy utilization by microalgae

(2012) Zoee Perrine et al.   Algal Research-Biomass Biofuels and Bioproducts

Evolution and functional properties of Photosystem II light harvesting complexes in eukaryotes

(2011) Matteo Ballottari et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Quenching inArabidopsis thalianaMutants Lacking Monomeric Antenna Proteins of Photosystem II

(2011) Yuliya Miloslavina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acclimation ofChlamydomonas reinhardtiito Different Growth Irradiances

(2011) Giulia Bonente et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Photosystem I ofChlamydomonas reinhardtiiContains Nine Light-harvesting Complexes (Lhca) Located on One Side of the Core

(2011) Bartlomiej Drop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Chloroplast Calcium Sensor CAS Is Required for Photoacclimation inChlamydomonas reinhardtii

(2011) Dimitris Petroutsos et al.   PLANT CELL

Assembly of the Light-Harvesting Chlorophyll Antenna in the Green Alga Chlamydomonas reinhardtii Requires Expression of the TLA2-CpFTSY Gene

(2011) H. Kirst et al.   PLANT PHYSIOLOGY

Isoprenoid biosynthesis in eukaryotic phototrophs: A spotlight on algae

(2011) Martin Lohr et al.   PLANT SCIENCE

Improving photosynthesis for algal biofuels: toward a green revolution

(2011) Patrick G. Stephenson et al.   TRENDS IN BIOTECHNOLOGY

Analysis of LhcSR3, a Protein Essential for Feedback De-Excitation in the Green Alga Chlamydomonas reinhardtii

(2011) Giulia Bonente et al.   PLOS BIOLOGY

Functional Hybrid Rubisco Enzymes with Plant Small Subunits and Algal Large Subunits

(2010) Todor Genkov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic engineering of fatty acid chain length in Phaeodactylum tricornutum

(2010) Randor Radakovits et al.   METABOLIC ENGINEERING

Advancing Our Understanding and Capacity to Engineer Nature's CO2-Sequestering Enzyme, Rubisco

(2010) S. M. Whitney et al.   PLANT PHYSIOLOGY

Physcomitrella patens mutants affected on heat dissipation clarify the evolution of photoprotection mechanisms upon land colonization

(2010) A. Alboresi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhancement of lipid production using biochemical, genetic and transcription factor engineering approaches

(2009) Noémie Manuelle Dorval Courchesne et al.   JOURNAL OF BIOTECHNOLOGY

An ancient light-harvesting protein is critical for the regulation of algal photosynthesis

(2009) Graham Peers et al.   NATURE

Solar energy conversion efficiencies in photosynthesis: Minimizing the chlorophyll antennae to maximize efficiency

(2009) Anastasios Melis   PLANT SCIENCE

Photosynthetic energy conversion: natural and artificial

(2008) James Barber   CHEMICAL SOCIETY REVIEWS

The Phaeodactylum genome reveals the evolutionary history of diatom genomes

(2008) Chris Bowler et al.   NATURE

In Silico and Biochemical Analysis of Physcomitrella patens Photosynthetic Antenna: Identification of Subunits which Evolved upon Land Adaptation

(2008) Alessandro Alboresi et al.   PLoS One

A type II NAD(P)H dehydrogenase mediates light-independent plastoquinone reduction in the chloroplast of Chlamydomonas

(2008) F. Jans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Architecture of a Charge-Transfer State Regulating Light Harvesting in a Plant Antenna Protein

(2008) T. K. Ahn et al.   SCIENCE