mTORC1-Rps15 Axis Contributes to the Mechanisms Underlying Global Translation Reduction During Senescence of Mouse Embryonic Fibroblasts

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Thallium(I) treatment induces nucleolar stress to stop protein synthesis and cell growth

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Signaling Pathways Involved in the Regulation of mRNA Translation

(2018) Philippe P. Roux et al.   MOLECULAR AND CELLULAR BIOLOGY

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(2018) Aleksandra S. Anisimova et al.   Aging-US

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(2018) Soyoung Lee et al.   NATURE CELL BIOLOGY

Pathways of cellular proteostasis in aging and disease

(2017) Courtney L. Klaips et al.   JOURNAL OF CELL BIOLOGY

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Alterations of the translation apparatus during aging and stress response

(2017) Yulia Gonskikh et al.   MECHANISMS OF AGEING AND DEVELOPMENT

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Dnmt2/Trdmt1 as Mediator of RNA Polymerase II Transcriptional Activity in Cardiac Growth

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Mechanism and biological role of Dnmt2 in Nucleic Acid Methylation

(2016) Albert Jeltsch et al.   RNA Biology

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

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Cellular senescence in aging and age-related disease: from mechanisms to therapy

(2015) Bennett G Childs et al.   NATURE MEDICINE

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

CACUL1/CAC1 Regulates the Antioxidant Response by Stabilizing Nrf2

(2015) Yu Kigoshi et al.   Scientific Reports

Translatome profiling: methods for genome-scale analysis of mRNA translation

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The Hallmarks of Aging

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Ribosomal protein S6 kinase activity controls the ribosome biogenesis transcriptional program

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Less is more: improving proteostasis by translation slow down

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Stable isotope-labelling analysis of the impact of inhibition of the mammalian target of rapamycin on protein synthesis

(2012) Yilin Huo et al.   BIOCHEMICAL JOURNAL

TOR Signaling and Rapamycin Influence Longevity by Regulating SKN-1/Nrf and DAF-16/FoxO

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A unifying model for mTORC1-mediated regulation of mRNA translation

(2012) Carson C. Thoreen et al.   NATURE

The translational landscape of mTOR signalling steers cancer initiation and metastasis

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Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

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DNA damage response activation in mouse embryonic fibroblasts undergoing replicative senescence and following spontaneous immortalization

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mTOR signaling regulates the processing of pre-rRNA in human cells

(2011) Valentina Iadevaia et al.   NUCLEIC ACIDS RESEARCH

Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

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A scaling normalization method for differential expression analysis of RNA-seq data

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(2009) M. D. Robinson et al.   BIOINFORMATICS

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

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SUnSET, a nonradioactive method to monitor protein synthesis

(2009) Enrico K Schmidt et al.   NATURE METHODS

The role of human ribosomal proteins in the maturation of rRNA and ribosome production

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