Joining forces: the need to combine science and ethics to address problems of validity and translation in neuropsychiatry research using animal models

Animal to human translation: a systematic scoping review of reported concordance rates

(2019) Cathalijn H. C. Leenaars et al.   Journal of Translational Medicine

Common functional networks in the mouse brain revealed by multi-centre resting-state fMRI analysis

(2019) Joanes Grandjean et al.   NEUROIMAGE

Harm–benefit analysis – what is the added value? A review of alternative strategies for weighing harms and benefits as part of the assessment of animal research

(2018) Herwig Grimm et al.   LABORATORY ANIMALS

The bench is closer to the bedside than we think: Uncovering the ethical ties between preclinical researchers in translational neuroscience and patients in clinical trials

(2018) Mark Yarborough et al.   PLOS BIOLOGY

Pharmacological manipulations in animal models of anorexia and binge eating in relation to humans

(2014) M A van Gestel et al.   BRITISH JOURNAL OF PHARMACOLOGY

Crazy Like a Fox

(2014) MICHAEL D. H. ROLLIN et al.   CAMBRIDGE QUARTERLY OF HEALTHCARE ETHICS

Increasing value and reducing waste in research design, conduct, and analysis

(2014) John P A Ioannidis et al.   LANCET

Preclinical models: Needed in translation? A Pro/Con debate

(2014) Thomas Philips et al.   MOVEMENT DISORDERS

Look back in anger – what clinical studies tell us about preclinical work

(2014) Thomas Hartung   ALTEX-Alternatives to Animal Experimentation

Is animal research sufficiently evidence based to be a cornerstone of biomedical research?

(2014) P. Pound et al.   BMJ-British Medical Journal

Toward the future of psychiatric diagnosis: the seven pillars of RDoC

(2013) Bruce N Cuthbert et al.   BMC Medicine

The use of mouse models to unravel genetic architecture of physical activity: a review

(2013) E. Kostrzewa et al.   GENES BRAIN AND BEHAVIOR

A rat in the labyrinth of anorexia nervosa: Contributions of the activity-based anorexia rodent model to the understanding of anorexia nervosa

(2013) Emilio Gutierrez   INTERNATIONAL JOURNAL OF EATING DISORDERS

Assessment of Physical Activity in Anorexia Nervosa and Treatment Outcome

(2013) MARTA ALBERTI et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Threats to Validity in the Design and Conduct of Preclinical Efficacy Studies: A Systematic Review of Guidelines for In Vivo Animal Experiments

(2013) Valerie C. Henderson et al.   PLOS MEDICINE

Progress in Using Systematic Reviews of Animal Studies to Improve Translational Research

(2013) C. R. Hooijmans et al.   PLOS MEDICINE

Animal models and conserved processes

(2012) Ray Greek et al.   Theoretical Biology and Medical Modelling

Predicting Harms and Benefits in Translational Trials: Ethics, Evidence, and Uncertainty

(2011) Jonathan Kimmelman et al.   PLOS MEDICINE

The Diagnosis of Mental Disorders: The Problem of Reification

(2010) Steven E. Hyman   Annual Review of Clinical Psychology

Animal models of neuropsychiatric disorders

(2010) Eric J Nestler et al.   NATURE NEUROSCIENCE

Can Animal Models of Disease Reliably Inform Human Studies?

(2010) H. Bart van der Worp et al.   PLOS MEDICINE

Is the use of sentient animals in basic research justifiable?

(2010) Ray Greek et al.   Philosophy Ethics and Humanities in Medicine

Uncertainty in the Translation of Preclinical Experiments to Clinical Trials. Why do Most Phase III Clinical Trials Fail?

(2009) Pedro Lowenstein et al.   CURRENT GENE THERAPY

“I'm not physically active - I only go for walks”: Physical activity in patients with longstanding eating disorders

(2009) Solfrid Bratland-Sanda et al.   INTERNATIONAL JOURNAL OF EATING DISORDERS

Letters to the Editor

(2009)   JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION

Different views on ethics: how animal ethics is situated in a committee culture

(2009) M Ideland   JOURNAL OF MEDICAL ETHICS

Are animal models predictive for humans?

(2009) Niall Shanks et al.   Philosophy Ethics and Humanities in Medicine

Medical progress depends on animal models – doesn't it?

(2008) Susan Green   JOURNAL OF THE ROYAL SOCIETY OF MEDICINE

Medical progress depends on animal models - doesn't it?

(2008) Robert AJ Matthews   JOURNAL OF THE ROYAL SOCIETY OF MEDICINE

Removing Obstacles in Neuroscience Drug Discovery: The Future Path for Animal Models

(2008) Athina Markou et al.   NEUROPSYCHOPHARMACOLOGY

Relevance of animal models to human eating disorders and obesity

(2008) Regina C. Casper et al.   PSYCHOPHARMACOLOGY