Proneural and mesenchymal glioma stem cells display major differences in splicing and lncRNA profiles

Glioblastoma Stem-Like Cells, Metabolic Strategy to Kill a Challenging Target

(2019) Delphine Garnier et al.   Frontiers in Oncology

Emerging Roles of Primary Cilia in Glioma

(2019) Matthew R. Sarkisian et al.   Frontiers in Cellular Neuroscience

A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications

(2019) Matthieu Gobin et al.   CANCER RESEARCH

SOX21-AS1 is associated with clinical stage and regulates cell proliferation in nephroblastoma

(2019) Jingxiu Zhang et al.   BIOSCIENCE REPORTS

Long noncoding RNA MYOSLID promotes invasion and metastasis by modulating the partial epithelial-mesenchymal transition program in head and neck squamous cell carcinoma

(2019) Hong-Gang Xiong et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Long non‐coding RNA MYOSLID functions as a competing endogenous RNA to regulate MCL‐1 expression by sponging miR‐29c‐3p in gastric cancer

(2019) Yuying Han et al.   CELL PROLIFERATION

Hypomethylation of the lncRNA SOX21-AS1 has clinical prognostic value in cervical cancer

(2019) Ruijie Wang et al.   LIFE SCIENCES

LncRNA SOX21-AS1 is associated with progression of hepatocellular carcinoma and predicts prognosis through epigenetically silencing p21

(2018) Congxin Wei et al.   BIOMEDICINE & PHARMACOTHERAPY

CRNDE: An important oncogenic long non-coding RNA in human cancers

(2018) Jiaming Zhang et al.   CELL PROLIFERATION

Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma

(2018) Rajendra P. Pangeni et al.   Epigenetics

Splicing regulation by long noncoding RNAs

(2018) Natali Romero-Barrios et al.   NUCLEIC ACIDS RESEARCH

Genetic landscape of long noncoding RNA (lncRNAs) in glioblastoma: identification of complex lncRNA regulatory networks and clinically relevant lncRNAs in glioblastoma

(2018) Yashna Paul et al.   Oncotarget

Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types

(2018) Michael Seiler et al.   Cell Reports

Systematic Analysis of Splice-Site-Creating Mutations in Cancer

(2018) Reyka G. Jayasinghe et al.   Cell Reports

Cell Cycle Changes after Glioblastoma Stem Cell Irradiation: The Major Role of RAD51

(2018) Gaelle Tachon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

The diagnostic and prognostic significance of long non-coding RNA CRNDE in pan-cancer based on TCGA, GEO and comprehensive meta–analysis

(2018) Zhu Hongzhen et al.   PATHOLOGY RESEARCH AND PRACTICE

RNA processing as an alternative route to attack glioblastoma

(2017) Fabiana Marcelino Meliso et al.   HUMAN GENETICS

CRNDE Expression Positively Correlates with EGFR Activation and Modulates Glioma Cell Growth

(2017) Karrie Mei-Yee Kiang et al.   Targeted Oncology

PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas

(2017) Robert F. Koncar et al.   Oncotarget

Identification of a Druggable Pathway Controlling Glioblastoma Invasiveness

(2017) Nora Pencheva et al.   Cell Reports

Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma

(2016) Vladimir Amani et al.   BMC CANCER

Determination of a Comprehensive Alternative Splicing Regulatory Network and Combinatorial Regulation by Key Factors during the Epithelial-to-Mesenchymal Transition

(2016) Yueqin Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation

(2016) Takashi Shingu et al.   NATURE GENETICS

GlioVis data portal for visualization and analysis of brain tumor expression datasets

(2016) Robert L. Bowman et al.   NEURO-ONCOLOGY

PCM1 Depletion Inhibits Glioblastoma Cell Ciliogenesis and Increases Cell Death and Sensitivity to Temozolomide

(2016) Lan B. Hoang-Minh et al.   Translational Oncology

Lineage-Restricted OLIG2-RTK Signaling Governs the Molecular Subtype of Glioma Stem-like Cells

(2016) Robert Kupp et al.   Cell Reports

Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition

(2016) Anna Segerman et al.   Cell Reports

Aberrant DNA hypermethylation-silenced SOX21-AS1 gene expression and its clinical importance in oral cancer

(2016) Cheng-Mei Yang et al.   Clinical Epigenetics

CRNDE, a long-noncoding RNA, promotes glioma cell growth and invasion through mTOR signaling

(2015) Yunliang Wang et al.   CANCER LETTERS

The role of glioma stem cells in chemotherapy resistance and glioblastoma multiforme recurrence

(2015) Brenda Auffinger et al.   Expert Review of Neurotherapeutics

The emerging role of lncRNAs in cancer

(2015) Maite Huarte   NATURE MEDICINE

Identification of recurrent regulated alternative splicing events across human solid tumors

(2015) Miri Danan-Gotthold et al.   NUCLEIC ACIDS RESEARCH

Prp40 pre-mRNA processing factor 40 homolog B (PRPF40B) associates with SF1 and U2AF65and modulates alternative pre-mRNA splicing in vivo

(2015) Soraya Becerra et al.   RNA

RTVP-1 regulates glioma cell migration and invasion via interaction with N-WASP and hnRNPK

(2015) Amotz Ziv-Av et al.   Oncotarget

PKM2 promotes glucose metabolism and cell growth in gliomas through a mechanism involving a let-7a/c-Myc/hnRNPA1 feedback loop

(2015) Wenkang Luan et al.   Oncotarget

Inhibition of DNA-repair genes Ercc1 and Mgmt enhances temozolomide efficacy in gliomas treatment: a pre-clinical study

(2015) Sandra G. Boccard et al.   Oncotarget

The role of glioma stem cells in chemotherapy resistance and glioblastoma multiforme recurrence

(2015) Brenda Auffinger et al.   Expert Review of Neurotherapeutics

Molecular and Cellular Mechanisms of Action of Tumour Suppressor GAS5 LncRNA

(2015) Mark Pickard et al.   Genes

Long Non-Coding RNAs: The Key Players in Glioma Pathogenesis

(2015) Karrie Kiang et al.   Cancers

FANCD2 re-expression is associated with glioma grade and chemical inhibition of the Fanconi Anaemia pathway sensitises gliomas to chemotherapeutic agents

(2015) Abhijit A. Patil et al.   Oncotarget

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Discovery and saturation analysis of cancer genes across 21 tumour types

(2014) Michael S. Lawrence et al.   NATURE

A census of human RNA-binding proteins

(2014) Stefanie Gerstberger et al.   NATURE REVIEWS GENETICS

Response-Predictive Gene Expression Profiling of Glioma Progenitor Cells In Vitro

(2014) Sylvia Moeckel et al.   PLoS One

rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data

(2014) Shihao Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma

(2013) Krishna P.L. Bhat et al.   CANCER CELL

Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A

(2013) C. G. Hubert et al.   GENES & DEVELOPMENT

AURKA Governs Self-Renewal Capacity in Glioma-Initiating Cells via Stabilization/Activation of  -catenin/Wnt Signaling

(2013) Z. Xia et al.   MOLECULAR CANCER RESEARCH

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3

(2013) P. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

Comprehensive identification of mutational cancer driver genes across 12 tumor types

(2013) David Tamborero et al.   Scientific Reports

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Heterogeneous Nuclear Ribonucleoprotein C1/C2 Controls the Metastatic Potential of Glioblastoma by Regulating PDCD4

(2012) Y. M. Park et al.   MOLECULAR AND CELLULAR BIOLOGY

The spliceosome as a target of novel antitumour drugs

(2012) Sophie Bonnal et al.   NATURE REVIEWS DRUG DISCOVERY

CRNDE: A Long Non-Coding RNA Involved in CanceR, Neurobiology, and DEvelopment

(2012) Blake C. Ellis et al.   Frontiers in Genetics

Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas

(2011) Clare V LeFave et al.   EMBO JOURNAL

Regulation of alternative splicing by the core spliceosomal machinery

(2011) A. L. Saltzman et al.   GENES & DEVELOPMENT

REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms

(2011) Fran Supek et al.   PLoS One

Fast and SNP-tolerant detection of complex variants and splicing in short reads

(2010) T. D. Wu et al.   BIOINFORMATICS

Aurora kinase A as a rational target for therapy in glioblastoma

(2010) Valerie N. Barton et al.   Journal of Neurosurgery-Pediatrics

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Primary ciliogenesis defects are associated with human astrocytoma/glioblastoma cells

(2009) Joanna J Moser et al.   BMC CANCER

Relationship between methylation status of ERCC1 promoter and radiosensitivity in glioma cell lines

(2009) Zhi-Gang Liu et al.   CELL BIOLOGY INTERNATIONAL

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

EXPRESSION OF CRM1 IN HUMAN GLIOMAS AND ITS SIGNIFICANCE IN P27 EXPRESSION AND CLINICAL PROGNOSIS

(2009) Aiguo Shen et al.   NEUROSURGERY