Induction of Cyclooxygenase-2 by Overexpression of the Human NADPH Oxidase 5 (NOX5) Gene in Aortic Endothelial Cells

Inducible cardiac-specific overexpression of cyclooxygenase-2 (COX-2) confers resistance to ischemia/reperfusion injury

(2019) Yiru Guo et al.   BASIC RESEARCH IN CARDIOLOGY

NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets

(2019) Yixuan Zhang et al.   Nature Reviews Cardiology

Isoform-selective NADPH oxidase inhibitor panel for pharmacological target validation

(2019) Vu Thao-Vi Dao et al.   FREE RADICAL BIOLOGY AND MEDICINE

18β-Glycyrrhetinic acid mitigates radiation-induced skin damage via NADPH oxidase/ROS/p38MAPK and NF-κB pathways

(2018) Li Su et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

ROS and redox signaling in myocardial ischemia-reperfusion injury and cardioprotection

(2018) Susana Cadenas   FREE RADICAL BIOLOGY AND MEDICINE

NADPH oxidase 5 promotes proliferation and fibrosis in human hepatic stellate cells

(2018) Aitor Andueza et al.   FREE RADICAL BIOLOGY AND MEDICINE

Up-regulation of COX-2 and mPGES-1 by 27-hydroxycholesterol and 4-hydroxynonenal: A crucial role in atherosclerotic plaque instability

(2018) Simona Gargiulo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Resveratrol inhibits urban particulate matter-induced COX-2/PGE 2 release in human fibroblast-like synoviocytes via the inhibition of activation of NADPH oxidase/ROS/NF-κB

(2017) Ming-Horng Tsai et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cardioprotective Effect of Resveratrol in a Postinfarction Heart Failure Model

(2017) Adam Riba et al.   Oxidative Medicine and Cellular Longevity

Atorvastatin attenuates plaque vulnerability by downregulation of EMMPRIN expression via COX-2/PGE2 pathway

(2017) Xing Liang et al.   Experimental and Therapeutic Medicine

A Variant in COX-2 Gene Is Associated with Left Main Coronary Artery Disease and Clinical Outcomes of Coronary Artery Bypass Grafting

(2017) Hanning Liu et al.   Biomed Research International

Cardiovascular effects of cyclooxygenase-2 inhibitors: a mechanistic and clinical perspective

(2016) Carlo Patrono   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Reactive Oxygen Species in Pathogenesis of Atherosclerosis

(2015) Nikolay Goncharov et al.   CURRENT PHARMACEUTICAL DESIGN

Enzymatic regulation and functional relevance of NOX5

(2015) Feng Chen et al.   CURRENT PHARMACEUTICAL DESIGN

Ageing, metabolism and cardiovascular disease

(2015) Sarah Costantino et al.   JOURNAL OF PHYSIOLOGY-LONDON

Pioglitazone reduces angiotensin II-induced COX-2 expression through inhibition of ROS production and ET-1 transcription in vascular cells from spontaneously hypertensive rats

(2014) Jose V. Pérez-Girón et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Endosulfan induces COX-2 expression via NADPH oxidase and the ROS, MAPK, and Akt pathways

(2014) Hyung Gyun Kim et al.   ARCHIVES OF TOXICOLOGY

Angiotensin II and Vascular Injury

(2014) Augusto C. Montezano et al.   CURRENT HYPERTENSION REPORTS

Association of cyclooxygenase-2 genetic variant with cardiovascular disease

(2014) Stephanie Ross et al.   EUROPEAN HEART JOURNAL

Regulation of NADPH Oxidase 5 by Protein Kinase C Isoforms

(2014) Feng Chen et al.   PLoS One

Eupafolin inhibits PGE2 production and COX2 expression in LPS-stimulated human dermal fibroblasts by blocking JNK/AP-1 and Nox2/p47phox pathway

(2014) Ming-Horng Tsai et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Genipin induces cyclooxygenase-2 expression via NADPH oxidase, MAPKs, AP-1, and NF-κB in RAW 264.7 cells

(2013) Tilak Khanal et al.   FOOD AND CHEMICAL TOXICOLOGY

The role of prostaglandin E2 in human vascular inflammation

(2013) I. Gomez et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

NOX5 Expression Is Increased in Intramyocardial Blood Vessels and Cardiomyocytes after Acute Myocardial Infarction in Humans

(2012) Nynke E. Hahn et al.   AMERICAN JOURNAL OF PATHOLOGY

Expression and functional significance of NADPH oxidase 5 (Nox5) and its splice variants in human blood vessels

(2012) Deepesh Pandey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

New Strategies for Echocardiographic Evaluation of Left Ventricular Function in a Mouse Model of Long-Term Myocardial Infarction

(2012) Carolina Benavides-Vallve et al.   PLoS One

The Nox Family of NADPH Oxidases: Friend or Foe of the Vascular System?

(2011) Ina Takac et al.   CURRENT HYPERTENSION REPORTS

Sphingosylphosphorylcholine down-regulates filaggrin gene transcription through NOX5-based NADPH oxidase and cyclooxygenase-2 in human keratinocytes

(2010) Hyun Choi et al.   BIOCHEMICAL PHARMACOLOGY

Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 5 (Nox5) Regulation by Angiotensin II and Endothelin-1 Is Mediated via Calcium/Calmodulin-Dependent, Rac-1-Independent Pathways in Human Endothelial Cells

(2010) Augusto C. Montezano et al.   CIRCULATION RESEARCH

Reactive oxygen species and vascular biology: implications in human hypertension

(2010) Rhian M Touyz et al.   HYPERTENSION RESEARCH

Titanium particles stimulate COX-2 expression in synovial fibroblasts through an oxidative stress-induced, calpain-dependent, NF-κB pathway

(2009) Xiaochao Wei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Calcium-Dependent NOX5 Nicotinamide Adenine Dinucleotide Phosphate Oxidase Contributes to Vascular Oxidative Stress in Human Coronary Artery Disease

(2008) Tomasz J. Guzik et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY