The Crosstalk between Cardiac Lipotoxicity and Mitochondrial Oxidative Stress in the Cardiac Alterations in Diet-Induced Obesity in Rats

The Impact of Cardiac Lipotoxicity on Cardiac Function and Mirnas Signature in Obese and Non-Obese Rats with Myocardial Infarction

(2019) Gema Marín-Royo et al.   Scientific Reports

Preservation of Acyl-CoA Attenuates Pathological and Metabolic Cardiac Remodeling Through Selective Lipid Trafficking

(2019) Joseph R. Goldenberg et al.   CIRCULATION

Myeloid differentiation protein 1 protected myocardial function against high‐fat stimulation induced pathological remodelling

(2019) Cai‐Jie Shen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes

(2019) Chandramohan Chitraju et al.   JOURNAL OF LIPID RESEARCH

High-density lipoprotein ameliorates palmitic acid-induced lipotoxicity and oxidative dysfunction in H9c2 cardiomyoblast cells via ROS suppression

(2019) Kuen-Ming Wu et al.   Nutrition & Metabolism

Targeting a ceramide double bond improves insulin resistance and hepatic steatosis

(2019) Bhagirath Chaurasia et al.   SCIENCE

The role of mitochondrial oxidative stress in the metabolic alterations in diet-induced obesity in rats

(2019) Gema Marín-Royo et al.   FASEB JOURNAL

Role of CyPA in cardiac hypertrophy and remodeling

(2019) Mengfei Cao et al.   BIOSCIENCE REPORTS

Nuclear miR-320 Mediates Diabetes-Induced Cardiac Dysfunction by Activating Transcription of Fatty Acid Metabolic Genes to Cause Lipotoxicity in the Heart

(2019) Huaping Li et al.   CIRCULATION RESEARCH

Sphingomyelin phosphodiesterase 1 (SMPD1) mediates the attenuation of myocardial infarction-induced cardiac fibrosis by astaxanthin

(2018) Yu Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dietary fat is a key determinant in balancing mitochondrial dynamics in heart failure: a novel mechanism underlying the obesity paradox

(2018) Matteo De Rosa et al.   CARDIOVASCULAR RESEARCH

Could Ceramides Become the New Cholesterol?

(2018) Scott A. Summers   Cell Metabolism

Plasma levels of free fatty acids correlate with type 2 diabetes mellitus

(2018) Sandro Spiller et al.   DIABETES OBESITY & METABOLISM

Inhibition of galectin-3 ameliorates the consequences of cardiac lipotoxicity in a rat model of diet-induced obesity

(2018) Gema Marín-Royo et al.   Disease Models & Mechanisms

A role for fumarate hydratase in mediating oxidative effects of galectin-3 in human cardiac fibroblasts

(2018) Jaime Ibarrola et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Angiotensin II upregulates cyclophilin A by enhancing ROS production in rat cardiomyocytes

(2018) Hangyu Tian et al.   Molecular Medicine Reports

Coconut Oil Aggravates Pressure Overload-Induced Cardiomyopathy without Inducing Obesity, Systemic Insulin Resistance, or Cardiac Steatosis

(2017) Ilayaraja Muthuramu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Abdominal Obesity Is Associated With an Increased Risk of All-Cause Mortality in Patients With HFpEF

(2017) Tetsuro Tsujimoto et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Treatment with antioxidants ameliorates oxidative damage in a mouse model of propionic acidemia

(2017) Ana Rivera-Barahona et al.   MOLECULAR GENETICS AND METABOLISM

Western diet increases cardiac ceramide content in healthy and hypertrophied hearts

(2017) T.J. Butler et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

The role of oxidative stress in the crosstalk between leptin and mineralocorticoid receptor in the cardiac fibrosis associated with obesity

(2017) Josué Gutiérrez-Tenorio et al.   Scientific Reports

Lipid Use and Misuse by the Heart

(2016) P. Christian Schulze et al.   CIRCULATION RESEARCH

Type 2 Diabetes Treatment in the Patient with Obesity

(2016) Steven K. Malin et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Mitochondrial oxidative stress during cardiac lipid overload causes intracellular calcium leak and arrhythmia

(2016) Leroy C. Joseph et al.   HEART RHYTHM

Dihydroceramides: From Bit Players to Lead Actors

(2015) Monowarul Mobin Siddique et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fatty acids and cardiac disease: fuel carrying a message

(2014) M. van Bilsen et al.   Acta Physiologica

Leptin induces cardiac fibrosis through galectin-3, mTOR and oxidative stress

(2014) Ernesto Martínez-Martínez et al.   JOURNAL OF HYPERTENSION

Towards a reproducible protocol for repetitive and semi-quantitative rat brain imaging with 18 F-FDG: Exemplified in a memantine pharmacological challenge

(2014) Steven Deleye et al.   NEUROIMAGE

Metabolism and function of mitochondrial cardiolipin

(2014) Mindong Ren et al.   PROGRESS IN LIPID RESEARCH

Functional role of cardiolipin in mitochondrial bioenergetics

(2013) Giuseppe Paradies et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Evaluation of the cardiolipin biosynthetic pathway and its interactions in the diabetic heart

(2013) Tara L. Croston et al.   LIFE SCIENCES

Insulin Resistance: Metabolic Mechanisms and Consequences in the Heart

(2012) E. Dale Abel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila

(2011) H.-Y. Lim et al.   GENES & DEVELOPMENT

Altered Glutathione Homeostasis in Heart Augments Cardiac Lipotoxicity Associated with Diet-induced Obesity in Mice

(2011) Sanjoy Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ceramides as modulators of cellular and whole-body metabolism

(2011) Benjamin T. Bikman et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial Targeted Antioxidant Peptide Ameliorates Hypertensive Cardiomyopathy

(2011) Dao-Fu Dai et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation

(2011) A. S. Rambold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The complexity of cardiolipin in health and disease

(2011) Steven M. Claypool et al.   TRENDS IN BIOCHEMICAL SCIENCES

Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria

(2010) Dao-Fu Dai et al.   AGING CELL

Cardiolipin Remodeling by ALCAT1 Links Oxidative Stress and Mitochondrial Dysfunction to Obesity

(2010) Jia Li et al.   Cell Metabolism

Mitochondrial cyclophilin-D as a potential therapeutic target for post-myocardial infarction heart failure

(2010) Shiang Y. Lim et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

DGAT1 Expression Increases Heart Triglyceride Content but Ameliorates Lipotoxicity

(2009) Li Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protection of C. elegans from Anoxia by HYL-2 Ceramide Synthase

(2009) V. Menuz et al.   SCIENCE

Body mass index and mortality in heart failure: A meta-analysis

(2008) Antigone Oreopoulos et al.   AMERICAN HEART JOURNAL

Role of diet and fuel overabundance in the development and progression of heart failure

(2008) D. J. Chess et al.   CARDIOVASCULAR RESEARCH

Increased Myocardial Susceptibility to Repetitive Ischemia With High-fat diet-induced Obesit

(2008) Geeta D. Thakker et al.   Obesity

Intracardiac lipid accumulation, lipoatrophy of muscle cells and expansion of myocardial infarction in type 2 diabetic patients

(2007) Andrei B. Borisov et al.   MICRON