N6-Methyladenosine Regulates the Expression and Secretion of TGFβ1 to Affect the Epithelial–Mesenchymal Transition of Cancer Cells

Inhibition of BRD4 suppresses the malignancy of breast cancer cells via regulation of Snail

(2019) Linlin Lu et al.   CELL DEATH AND DIFFERENTIATION

Transforming growth factor–β (TGF-β)–induced up-regulation of TGF-β receptors at the cell surface amplifies the TGF-β response

(2019) Dana Duan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail

(2019) Xinyao Lin et al.   Nature Communications

Multiple functions of m6A RNA methylation in cancer

(2018) Yutian Pan et al.   Journal of Hematology & Oncology

Novel insights on m6A RNA methylation in tumorigenesis: a double-edged sword

(2018) Shaoyun Wang et al.   Molecular Cancer

N 6 -Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response

(2018) Jun Zhou et al.   MOLECULAR CELL

Mechanism of N 6 -methyladenosine Modification and Its Emerging Role in Cancer

(2018) Sicong Zhang   PHARMACOLOGY & THERAPEUTICS

VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

(2018) Yanan Yue et al.   Cell Discovery

The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency

(2018) Alessandro Bertero et al.   NATURE

mRNA circularization by METTL3–eIF3h enhances translation and promotes oncogenesis

(2018) Junho Choe et al.   NATURE

m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer

(2018) Jun Liu et al.   NATURE CELL BIOLOGY

Epithelial-Mesenchymal Transition and Metastasis under the Control of Transforming Growth Factor β

(2018) Yutaro Tsubakihara et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cross-talk among writers, readers, and erasers of m6A regulates cancer growth and progression

(2018) Subbarayalu Panneerdoss et al.   Science Advances

RNase H1-Dependent Antisense Oligonucleotides Are Robustly Active in Directing RNA Cleavage in Both the Cytoplasm and the Nucleus

(2017) Xue-Hai Liang et al.   MOLECULAR THERAPY

Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control

(2017) Isaia Barbieri et al.   NATURE

N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3′-end processing

(2017) Marek Bartosovic et al.   NUCLEIC ACIDS RESEARCH

YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs

(2017) Ian A Roundtree et al.   eLife

Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases

(2016) Ping Wang et al.   MOLECULAR CELL

The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells

(2016) Shuibin Lin et al.   MOLECULAR CELL

Early dissemination seeds metastasis in breast cancer

(2016) Hedayatollah Hosseini et al.   NATURE

m6A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination

(2016) Irmgard U. Haussmann et al.   NATURE

m6A modulates neuronal functions and sex determination in Drosophila

(2016) Tina Lence et al.   NATURE

Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex

(2016) Xiang Wang et al.   NATURE

Mechanism of early dissemination and metastasis in Her2+ mammary cancer

(2016) Kathryn L. Harper et al.   NATURE

Regulation of the Bioavailability of TGF-β and TGF-β-Related Proteins

(2016) Ian B. Robertson et al.   Cold Spring Harbor Perspectives in Biology

Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients

(2016) A. Marcell Szász et al.   Oncotarget

Structural insights into the molecular mechanism of the m6A writer complex

(2016) Paweł Śledź et al.   eLife

Mechanisms of TGFβ-Induced Epithelial–Mesenchymal Transition

(2016) Aristidis Moustakas et al.   Journal of Clinical Medicine

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

(2015) Xiao Wang et al.   CELL

Latent TGF-β-binding proteins

(2015) Ian B. Robertson et al.   MATRIX BIOLOGY

Epithelial–Mesenchymal Plasticity: A Central Regulator of Cancer Progression

(2015) Xin Ye et al.   TRENDS IN CELL BIOLOGY

Reprogramming during epithelial to mesenchymal transition under the control of TGFβ

(2014) E-Jean Tan et al.   Cell Adhesion & Migration

RNA-Methylation-Dependent RNA Processing Controls the Speed of the Circadian Clock

(2013) Jean-Michel Fustin et al.   CELL

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

Choreographing Metastasis to the Tune of LTBP

(2011) Anupama Chandramouli et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Biomarkers for epithelial-mesenchymal transitions

(2009) Michael Zeisberg et al.   JOURNAL OF CLINICAL INVESTIGATION