Epithelial-Mesenchymal Transition and Metastasis under the Control of Transforming Growth Factor β

Nkx2.8 Inhibits Epithelial–Mesenchymal Transition in Bladder Urothelial Carcinoma via Transcriptional Repression ofTwist1

(2018) Chunping Yu et al.   CANCER RESEARCH

In vivo optical imaging of cancer cell function and tumor microenvironment

(2018) Takeshi Imamura et al.   CANCER SCIENCE

Involvement of partial EMT in cancer progression

(2018) Masao Saitoh   JOURNAL OF BIOCHEMISTRY

Genome-wide binding of transcription factor ZEB1 in triple-negative breast cancer cells

(2018) Varun Maturi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network

(2018) Xiaochao Tan et al.   JOURNAL OF CLINICAL INVESTIGATION

The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network

(2018) Xiaochao Tan et al.   JOURNAL OF CLINICAL INVESTIGATION

Genomewide binding of transcription factor Snail1 in triple-negative breast cancer cells

(2018) Varun Maturi et al.   Molecular Oncology

Tumour spheres with inverted polarity drive the formation of peritoneal metastases in patients with hypermethylated colorectal carcinomas

(2018) Olivier Zajac et al.   NATURE CELL BIOLOGY

Contextual determinants of TGFβ action in development, immunity and cancer

(2018) Charles J. David et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MiR-22 suppresses epithelial–mesenchymal transition in bladder cancer by inhibiting Snail and MAPK1/Slug/vimentin feedback loop

(2018) Mingjie Xu et al.   Cell Death & Disease

Laminin signals initiate the reciprocal loop that informs breast-specific gene expression and homeostasis by activating NO, p53 and microRNAs

(2018) Saori Furuta et al.   eLife

Identification of the tumour transition states occurring during EMT

(2018) Ievgenia Pastushenko et al.   NATURE

ΔNp63α Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas

(2018) Christopher G. Abraham et al.   Cell Reports

Leucine-rich repeat–containing G protein–coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial–mesenchymal transition

(2017) Weijia Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Time-lapsed, large-volume, high-resolution intravital imaging for tissue-wide analysis of single cell dynamics

(2017) David Entenberg et al.   METHODS

EMT and MET: necessary or permissive for metastasis?

(2017) Mohit Kumar Jolly et al.   Molecular Oncology

Upholding a role for EMT in breast cancer metastasis

(2017) Xin Ye et al.   NATURE

Upholding a role for EMT in pancreatic cancer metastasis

(2017) Nicole M. Aiello et al.   NATURE

A20 promotes metastasis of aggressive basal-like breast cancers through multi-monoubiquitylation of Snail1

(2017) Ji-Hyung Lee et al.   NATURE CELL BIOLOGY

The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

(2017) Angela M. Krebs et al.   NATURE CELL BIOLOGY

The Cdc42/Rac1 regulator CdGAP is a novel E-cadherin transcriptional co-repressor with Zeb2 in breast cancer

(2017) Y He et al.   ONCOGENE

Breast tumor cell-specific knockout ofTwist1inhibits cancer cell plasticity, dissemination, and lung metastasis in mice

(2017) Yixiang Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The transcription factor MAFK induces EMT and malignant progression of triple-negative breast cancer cells through its target GPNMB

(2017) Yukari Okita et al.   Science Signaling

USP17 is upregulated in osteosarcoma and promotes cell proliferation, metastasis, and epithelial–mesenchymal transition through stabilizing SMAD4

(2017) Chenyang Song et al.   TUMOR BIOLOGY

TGF-β Family Signaling in Epithelial Differentiation and Epithelial–Mesenchymal Transition

(2017) Kaoru Kahata et al.   Cold Spring Harbor Perspectives in Biology

Stabilization of the transcription factors slug and twist by the deubiquitinase dub3 is a key requirement for tumor metastasis

(2017) Yiwei Lin et al.   Oncotarget

The protein kinase SIK downregulates the polarity protein Par3

(2017) Michael Vanlandewijck et al.   Oncotarget

A novel ZEB1/HAS2 positive feedback loop promotes EMT in breast cancer

(2017) Bogdan-Tiberius Preca et al.   Oncotarget

Klf4 reduces stemness phenotype, triggers mesenchymal-epithelial transition (MET)-like molecular changes, and prevents tumor progression in nasopharygeal carcinoma

(2017) Xiqing Li et al.   Oncotarget

Whole-Body Profiling of Cancer Metastasis with Single-Cell Resolution

(2017) Shimpei I. Kubota et al.   Cell Reports

The transcription factor MAFK induces EMT and malignant progression of triple-negative breast cancer cells through its target GPNMB

(2017) Yukari Okita et al.   Science Signaling

Snail collaborates with EGR-1 and SP-1 to directly activate transcription of MMP 9 and ZEB1

(2017) Wen-Sheng Wu et al.   Scientific Reports

Transforming growth factor β as regulator of cancer stemness and metastasis

(2016) Claudia Bellomo et al.   BRITISH JOURNAL OF CANCER

AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation

(2016) Chia-Wei Li et al.   CANCER RESEARCH

Aberrant JMJD3 Expression Upregulates Slug to Promote Migration, Invasion, and Stem Cell–Like Behaviors in Hepatocellular Carcinoma

(2016) Bo Tang et al.   CANCER RESEARCH

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

MT1-MMP Activation of TGF-? Signaling Enables Intercellular Activation of an Epithelial-mesenchymal Transition Program in Cancer

(2016) Hoang-Lan Nguyen et al.   CURRENT CANCER DRUG TARGETS

Curcumin inhibits metastasis in human papillary thyroid carcinoma BCPAP cells via down-regulation of the TGF-β/Smad2/3 signaling pathway

(2016) Li Zhang et al.   EXPERIMENTAL CELL RESEARCH

Third harmonic generation microscopy of cells and tissue organization

(2016) Bettina Weigelin et al.   JOURNAL OF CELL SCIENCE

The DNA Damage Transducer RNF8 Facilitates Cancer Chemoresistance and Progression through Twist Activation

(2016) Hong-Jen Lee et al.   MOLECULAR CELL

Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition

(2016) Marco Sciacovelli et al.   NATURE

Metastatic colonization by circulating tumour cells

(2016) Joan Massagué et al.   NATURE

Mechanism of early dissemination and metastasis in Her2+ mammary cancer

(2016) Kathryn L. Harper et al.   NATURE

Synergistic action of master transcription factors controls epithelial-to-mesenchymal transition

(2016) Hongyuan Chang et al.   NUCLEIC ACIDS RESEARCH

Sulforaphane inhibits TGF-β-induced epithelial-mesenchymal transition of hepatocellular carcinoma cells via the reactive oxygen species-dependent pathway

(2016) JINSHENG WU et al.   ONCOLOGY REPORTS

miR-5003-3p promotes epithelial-mesenchymal transition in breast cancer cells through Snail stabilization and direct targeting of E-cadherin

(2016) Seo-Young Kwak et al.   Journal of Molecular Cell Biology

Upregulation of MiR-205 under hypoxia promotes epithelial–mesenchymal transition by targeting ASPP2

(2016) Xingwen Wang et al.   Cell Death & Disease

Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition

(2016) Asoka Banno et al.   Oncotarget

MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition

(2016) Huacheng Luo et al.   Cell Reports

A Histone Deacetylase Inhibitor Suppresses Epithelial-Mesenchymal Transition and Attenuates Chemoresistance in Biliary Tract Cancer

(2016) Takuya Sakamoto et al.   PLoS One

The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

(2015) Pierrick G.J. Fournier et al.   CANCER CELL

SND1 Acts Downstream of TGF 1 and Upstream of Smurf1 to Promote Breast Cancer Metastasis

(2015) L. Yu et al.   CANCER RESEARCH

TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation

(2015) D. J. Drasin et al.   CANCER RESEARCH

TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination

(2015) Gaia Cantelli et al.   CURRENT BIOLOGY

Long Non-coding RNAs (LncRNA) Regulated by Transforming Growth Factor (TGF) β

(2015) Edward J. Richards et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

(2015) Kari R. Fischer et al.   NATURE

Translational regulation of inhibin βA by TGFβ via the RNA-binding protein hnRNP E1 enhances the invasiveness of epithelial-to-mesenchymal transitioned cells

(2015) B V Howley et al.   ONCOGENE

The natural compound codonolactone attenuates TGF-β1-mediated epithelial-to-mesenchymal transition and motility of breast cancer cells

(2015) JIANJIANG FU et al.   ONCOLOGY REPORTS

Epithelial–Mesenchymal Plasticity: A Central Regulator of Cancer Progression

(2015) Xin Ye et al.   TRENDS IN CELL BIOLOGY

Combinatorial TGF-β attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells

(2015) So-Yeon Park et al.   Oncotarget

Disulfiram inhibits TGF-β-induced epithelial-mesenchymal transition and stem-like features in breast cancer via ERK/NF-κB/Snail pathway

(2015) Dan Han et al.   Oncotarget

Transforming Growth Factor-β1 Induced Epithelial Mesenchymal Transition is blocked by a chemical antagonist of translation factor eIF4E

(2015) K. A. Smith et al.   Scientific Reports

The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer

(2015) Anna Chen et al.   Oncotarget

Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors

(2015) Ming Xu et al.   Oncotarget

The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancer

(2014) Britta Weigelt et al.   ADVANCED DRUG DELIVERY REVIEWS

A Long Noncoding RNA Activated by TGF-β Promotes the Invasion-Metastasis Cascade in Hepatocellular Carcinoma

(2014) Ji-hang Yuan et al.   CANCER CELL

Network Modeling of TGF  Signaling in Hepatocellular Carcinoma Epithelial-to-Mesenchymal Transition Reveals Joint Sonic Hedgehog and Wnt Pathway Activation

(2014) S. N. Steinway et al.   CANCER RESEARCH

Regulation of Epithelial-Mesenchymal Transition through SUMOylation of Transcription Factors

(2014) M. V. Bogachek et al.   CANCER RESEARCH

The TGF -miR200-MIG6 Pathway Orchestrates the EMT-Associated Kinase Switch That Induces Resistance to EGFR Inhibitors

(2014) E. Izumchenko et al.   CANCER RESEARCH

Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression

(2014) L Bakiri et al.   CELL DEATH AND DIFFERENTIATION

TGF- -Induced Upregulation of malat1 Promotes Bladder Cancer Metastasis by Associating with suz12

(2014) Y. Fan et al.   CLINICAL CANCER RESEARCH

Signaling pathway cooperation in TGF-β-induced epithelial–mesenchymal transition

(2014) Rik Derynck et al.   CURRENT OPINION IN CELL BIOLOGY

Regulated intramembrane proteolysis of the TGFβ type I receptor conveys oncogenic signals

(2014) Shyam Kumar Gudey et al.   Future Oncology

Zeb1 and Snail1 engage miR-200f transcriptional and epigenetic regulation during EMT

(2014) Antonio Díaz-López et al.   INTERNATIONAL JOURNAL OF CANCER

Excessive Hyaluronan Production Promotes Acquisition of Cancer Stem Cell Signatures through the Coordinated Regulation of Twist and the Transforming Growth Factor β (TGF-β)-Snail Signaling Axis

(2014) Theerawut Chanmee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered N-Glycan Expression Profile in Epithelial-to-Mesenchymal Transition of NMuMG Cells Revealed by an Integrated Strategy Using Mass Spectrometry and Glycogene and Lectin Microarray Analysis

(2014) Zengqi Tan et al.   JOURNAL OF PROTEOME RESEARCH

TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion

(2014) Lukas D. Osborne et al.   MOLECULAR BIOLOGY OF THE CELL

Mesenchymal–endothelial transition contributes to cardiac neovascularization

(2014) Eric Ubil et al.   NATURE

Lysyl oxidase-like 2 (LOXL2) and E47 EMT factor: novel partners in E-cadherin repression and early metastasis colonization

(2014) G Canesin et al.   ONCOGENE

Slug is temporally regulated by cyclin E in cell cycle and controls genome stability

(2014) W-L Wang et al.   ONCOGENE

Signaling mechanisms of the epithelial-mesenchymal transition

(2014) D. M. Gonzalez et al.   Science Signaling

TGF-β Activation and Function in Immunity

(2013) Mark A. Travis et al.   Annual Review of Immunology

Fucosylated TGF-β receptors transduces a signal for epithelial–mesenchymal transition in colorectal cancer cells

(2013) M Hirakawa et al.   BRITISH JOURNAL OF CANCER

Nutlin-3 inhibits epithelial–mesenchymal transition by interfering with canonical transforming growth factor-β1-Smad-Snail/Slug axis

(2013) Yeping Wu et al.   CANCER LETTERS

The Malignant Brain Tumor (MBT) Domain Protein SFMBT1 Is an Integral Histone Reader Subunit of the LSD1 Demethylase Complex for Chromatin Association and Epithelial-to-mesenchymal Transition

(2013) Ming Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A complex containing LPP and  -actinin mediates TGF -induced migration and invasion of ErbB2-expressing breast cancer cells

(2013) E. Ngan et al.   JOURNAL OF CELL SCIENCE

Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β

(2013) Jenny G. Parvani et al.   MOLECULAR BIOLOGY OF THE CELL

Mammary epithelial cell interactions with fibronectin stimulate epithelial-mesenchymal transition

(2013) J Park et al.   ONCOGENE

Cadherin 6 Is a New RUNX2 Target in TGF-β Signalling Pathway

(2013) Valentina Sancisi et al.   PLoS One

TGF-β-Id1 Signaling Opposes Twist1 and Promotes Metastatic Colonization via a Mesenchymal-to-Epithelial Transition

(2013) Marko Stankic et al.   Cell Reports

Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

(2012) Alexandre Calon et al.   CANCER CELL

Metastatic Colonization Requires the Repression of the Epithelial-Mesenchymal Transition Inducer Prrx1

(2012) Oscar H. Ocaña et al.   CANCER CELL

miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions

(2012) Helge Siemens et al.   CELL CYCLE

Genome-wide analysis reveals that Smad3 and JMJD3 HDM co-activate the neural developmental program

(2012) C. Estaras et al.   DEVELOPMENT

Transcriptional Induction of Salt-inducible Kinase 1 by Transforming Growth Factor β Leads to Negative Regulation of Type I Receptor Signaling in Cooperation with the Smurf2 Ubiquitin Ligase

(2012) Peter Lönn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zyxin Is a Transforming Growth Factor-β (TGF-β)/Smad3 Target Gene That Regulates Lung Cancer Cell Motility via Integrin α5β1

(2012) Nikica Mise et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hic-5 promotes invadopodia formation and invasion during TGF-β–induced epithelial–mesenchymal transition

(2012) Jeanine Pignatelli et al.   JOURNAL OF CELL BIOLOGY

p53 regulates epithelial-mesenchymal transition induced by transforming growth factor β

(2012) Stefan Termén et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Matrix rigidity regulates a switch between TGF-β1–induced apoptosis and epithelial–mesenchymal transition

(2012) Jennifer L. Leight et al.   MOLECULAR BIOLOGY OF THE CELL

New dimensions in cell migration

(2012) Peter Friedl et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Efficient TGFβ-induced epithelial–mesenchymal transition depends on hyaluronan synthase HAS2

(2012) H Porsch et al.   ONCOGENE

Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion

(2012) A Sundqvist et al.   ONCOGENE

Establishment of a TGFβ-Induced Post-Transcriptional EMT Gene Signature

(2012) George S. Hussey et al.   PLoS One

Induction of epithelial–mesenchymal transition by transforming growth factor β

(2012) Aristidis Moustakas et al.   SEMINARS IN CANCER BIOLOGY

Cancer stem cells and epithelial–mesenchymal transition: Concepts and molecular links

(2012) Christina Scheel et al.   SEMINARS IN CANCER BIOLOGY

The Ins and Outs of the Epithelial to Mesenchymal Transition in Health and Disease

(2011) M. Angela Nieto   Annual Review of Cell and Developmental Biology

Twist1-Induced Invadopodia Formation Promotes Tumor Metastasis

(2011) Mark A. Eckert et al.   CANCER CELL

Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis

(2011) Myriam Labelle et al.   CANCER CELL

Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast

(2011) Christina Scheel et al.   CELL

Regulation of endothelial cell plasticity by TGF-β

(2011) Laurens A. van Meeteren et al.   CELL AND TISSUE RESEARCH

The TGFβ-Par6 polarity pathway: Linking the Par complex to EMT and breast cancer progression

(2011) Alicia M. Viloria-Petit et al.   CELL CYCLE

Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-β production and epithelial to mesenchymal transition

(2011) Daniel J. Schneider et al.   FASEB JOURNAL

Down-regulation of epithelial cadherin is required to initiate metastatic outgrowth of breast cancer

(2011) Michael K. Wendt et al.   MOLECULAR BIOLOGY OF THE CELL

Dynamic actin remodeling during epithelial–mesenchymal transition depends on increased moesin expression

(2011) Jennifer Haynes et al.   MOLECULAR BIOLOGY OF THE CELL

An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

(2011) Philip A. Gregory et al.   MOLECULAR BIOLOGY OF THE CELL

Identification of an mRNP Complex Regulating Tumorigenesis at the Translational Elongation Step

(2011) George S. Hussey et al.   MOLECULAR CELL

Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

(2011) Manav Korpal et al.   NATURE MEDICINE

Differential regulation of the two RhoA-specific GEF isoforms Net1/Net1A by TGF-β and miR-24: role in epithelial-to-mesenchymal transition

(2011) E Papadimitriou et al.   ONCOGENE

TGF-β drives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP

(2011) K Horiguchi et al.   ONCOGENE

Up-Regulation of Sonic Hedgehog Contributes to TGF-β1-Induced Epithelial to Mesenchymal Transition in NSCLC Cells

(2011) Ma'in Y. Maitah et al.   PLoS One

Myosin II isoform switching mediates invasiveness after TGF- -induced epithelial-mesenchymal transition

(2011) J. R. Beach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coordinating developmental signaling: novel roles for the Hippo pathway

(2011) Xaralabos Varelas et al.   TRENDS IN CELL BIOLOGY

TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer

(2011) Yabing Mu et al.   Nature Communications

The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1

(2010) Yiwei Lin et al.   EMBO JOURNAL

TGF-β-induced MiR-491-5p Expression Promotes Par-3 Degradation in Rat Proximal Tubular Epithelial Cells

(2010) Qin Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition

(2010) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY

TGF-β-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI

(2010) Arindam Chaudhury et al.   NATURE CELL BIOLOGY

Transforming growth factor-β-induced epithelial–mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression

(2010) M K Wendt et al.   ONCOGENE

Requirement of the histone demethylase LSD1 in Snai1-mediated transcriptional repression during epithelial-mesenchymal transition

(2010) T Lin et al.   ONCOGENE

The regulation of TGF  signal transduction

(2009) A. Moustakas et al.   DEVELOPMENT

Zyxin Mediates Actin Fiber Reorganization in Epithelial–Mesenchymal Transition and Contributes to Endocardial Morphogenesis

(2009) Masaki Mori et al.   MOLECULAR BIOLOGY OF THE CELL

A SNAIL1–SMAD3/4 transcriptional repressor complex promotes TGF-β mediated epithelial–mesenchymal transition

(2009) Theresa Vincent et al.   NATURE CELL BIOLOGY

Hepatic tumor–stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge

(2009) F van Zijl et al.   ONCOGENE

Collagen-based cell migration models in vitro and in vivo

(2009) Katarina Wolf et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Abrogation of TGFβ Signaling in Mammary Carcinomas Recruits Gr-1+CD11b+ Myeloid Cells that Promote Metastasis

(2008) Li Yang et al.   CANCER CELL

TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4

(2008) David Padua et al.   CELL

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

(2008) Ulrike Burk et al.   EMBO REPORTS

The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2

(2008) Manav Korpal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HMGA2 and Smads Co-regulate SNAIL1 Expression during Induction of Epithelial-to-Mesenchymal Transition

(2008) Sylvie Thuault et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TGFβ induces SIK to negatively regulate type I receptor kinase signaling

(2008) Marcin Kowanetz et al.   JOURNAL OF CELL BIOLOGY

MicroRNA-155 Is Regulated by the Transforming Growth Factor  /Smad Pathway and Contributes to Epithelial Cell Plasticity by Targeting RhoA

(2008) W. Kong et al.   MOLECULAR AND CELLULAR BIOLOGY

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

(2008) Alessandro Sorrentino et al.   NATURE CELL BIOLOGY

ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression

(2008) C Lahsnig et al.   ONCOGENE

The transcription factor snail represses Crumbs3 expression and disrupts apico-basal polarity complexes

(2008) E L Whiteman et al.   ONCOGENE