Targeting with nanoparticles for the therapeutic treatment of brain diseases

Mitochondria at the neuronal presynapse in health and disease

(2018) Michael J. Devine et al.   NATURE REVIEWS NEUROSCIENCE

Focus on Fundamentals: Achieving Effective Nanoparticle Targeting

(2018) Gregory T. Tietjen et al.   TRENDS IN MOLECULAR MEDICINE

Intra-articular biomaterials-assisted delivery to treat temporomandibular joint disorders

(2018) Khandmaa Dashnyam et al.   Journal of Tissue Engineering

Emerging properties of hydrogels in tissue engineering

(2018) Jung-Hwan Lee et al.   Journal of Tissue Engineering

Astroglia as a cellular target for neuroprotection and treatment of neuro-psychiatric disorders

(2017) Beihui Liu et al.   GLIA

cRGD peptide-installed epirubicin-loaded polymeric micelles for effective targeted therapy against brain tumors

(2017) S. Quader et al.   JOURNAL OF CONTROLLED RELEASE

Brain aging and neurodegeneration: from a mitochondrial point of view

(2017) Amandine Grimm et al.   JOURNAL OF NEUROCHEMISTRY

Neuronal protection against oxidative insult by polyanhydride nanoparticle-based mitochondria-targeted antioxidant therapy

(2017) Timothy M. Brenza et al.   Nanomedicine-Nanotechnology Biology and Medicine

Microglial Activation in Traumatic Brain Injury

(2017) Cornelius K. Donat et al.   Frontiers in Aging Neuroscience

The Role of Astrocytes in Neuroprotection after Brain Stroke: Potential in Cell Therapy

(2017) Andrea Becerra-Calixto et al.   Frontiers in Molecular Neuroscience

Blood–Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy

(2016) Tingting Lin et al.   ACS Nano

Mitochondria-Targeting Ceria Nanoparticles as Antioxidants for Alzheimer’s Disease

(2016) Hyek Jin Kwon et al.   ACS Nano

Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases

(2016) Mathieu Bourdenx et al.   Autophagy

Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier

(2016) David S. Hersh et al.   CURRENT PHARMACEUTICAL DESIGN

Movement and structure of mitochondria in oligodendrocytes and their myelin sheaths

(2016) Johanne E. Rinholm et al.   GLIA

Nanostructured Antagonist of Extrasynaptic NMDA Receptors

(2016) Alex Savchenko et al.   NANO LETTERS

Passage of Magnetic Tat-Conjugated Fe3O4@SiO2 Nanoparticles Across In Vitro Blood-Brain Barrier

(2016) Xueqin Zhao et al.   Nanoscale Research Letters

Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke

(2016) Zhongwu Liu et al.   PROGRESS IN NEUROBIOLOGY

Passage of Magnetic Tat-Conjugated Fe3O4@SiO2 Nanoparticles Across In Vitro Blood-Brain Barrier

(2016) Xueqin Zhao et al.   Nanoscale Research Letters

GM1-Modified Lipoprotein-like Nanoparticle: Multifunctional Nanoplatform for the Combination Therapy of Alzheimer’s Disease

(2015) Meng Huang et al.   ACS Nano

Myelin repair in vivo is increased by targeting oligodendrocyte precursor cells with nanoparticles encapsulating leukaemia inhibitory factor (LIF)

(2015) Sonja Rittchen et al.   BIOMATERIALS

Clathrin to Lipid Raft-Endocytosis via Controlled Surface Chemistry and Efficient Perinuclear Targeting of Nanoparticle

(2015) Atanu Chakraborty et al.   Journal of Physical Chemistry Letters

Increased brain uptake of targeted nanoparticles by adding an acid-cleavable linkage between transferrin and the nanoparticle core

(2015) Andrew J. Clark et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocyte Depletion Impairs Redox Homeostasis and Triggers Neuronal Loss in the Adult CNS

(2015) Bettina Schreiner et al.   Cell Reports

Neuronal Regulation of Schwann Cell Mitochondrial Ca2+ Signaling during Myelination

(2015) Daisuke Ino et al.   Cell Reports

Dendrimer Brain Uptake and Targeted Therapy for Brain Injury in a Large Animal Model of Hypothermic Circulatory Arrest

(2014) Manoj K. Mishra et al.   ACS Nano

Lipoprotein-Based Nanoparticles Rescue the Memory Loss of Mice with Alzheimer’s Disease by Accelerating the Clearance of Amyloid-Beta

(2014) Qingxiang Song et al.   ACS Nano

Paclitaxel loaded liposomes decorated with a multifunctional tandem peptide for glioma targeting

(2014) Yayuan Liu et al.   BIOMATERIALS

Squalenoyl adenosine nanoparticles provide neuroprotection after stroke and spinal cord injury

(2014) Alice Gaudin et al.   Nature Nanotechnology

The impact of microglial activation on blood-brain barrier in brain diseases

(2014) Anna Carolina Carvalho da Fonseca et al.   Frontiers in Cellular Neuroscience

Smuggling Drugs into the Brain: An Overview of Ligands Targeting Transcytosis for Drug Delivery across the Blood–Brain Barrier

(2014) Julia Georgieva et al.   Pharmaceutics

Role of astrocytes in major neurological disorders: The evidence and implications

(2013) Caterina Scuderi et al.   IUBMB LIFE

Enhanced Neuroprotective Effects of Resveratrol Delivered by Nanoparticles on Hydrogen Peroxide-Induced Oxidative Stress in Rat Cortical Cell Culture

(2013) Xiaowei Lu et al.   MOLECULAR PHARMACEUTICS

Glucose-Coated Gold Nanoparticles Transfer across Human Brain Endothelium and Enter Astrocytes In Vitro

(2013) Radka Gromnicova et al.   PLoS One

Engineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood-brain barrier

(2013) D. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PEGylated Nanoparticles Bind to and Alter Amyloid-Beta Peptide Conformation: Toward Engineering of Functional Nanomedicines for Alzheimer’s Disease

(2012) Davide Brambilla et al.   ACS Nano

Investigation of glucose-modified liposomes using polyethylene glycols with different chain lengths as the linkers for brain targeting

(2012) Fulan Xie et al.   International Journal of Nanomedicine

Dendrimer-Based Postnatal Therapy for Neuroinflammation and Cerebral Palsy in a Rabbit Model

(2012) S. Kannan et al.   Science Translational Medicine

Mitochondria as a Therapeutic Target for Aging and Neurodegenerative Diseases

(2011) P. H. Reddy et al.   Current Alzheimer Research

Transport of drugs across the blood–brain barrier by nanoparticles

(2011) Stefanie Wohlfart et al.   JOURNAL OF CONTROLLED RELEASE

Adenosine receptors and brain diseases: Neuroprotection and neurodegeneration

(2010) Catarina V. Gomes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery

(2010) Fabienne Danhier et al.   JOURNAL OF CONTROLLED RELEASE

Intrinsic targeting of inflammatory cells in the brain by polyamidoamine dendrimers upon subarachnoid administration

(2010) Hui Dai et al.   Nanomedicine

Oligodendrocytes: biology and pathology

(2009) Monika Bradl et al.   ACTA NEUROPATHOLOGICA

Self-assembled hyaluronic acid nanoparticles for active tumor targeting

(2009) Ki Young Choi et al.   BIOMATERIALS

Strategies to advance translational research into brain barriers

(2008) Edward Neuwelt et al.   LANCET NEUROLOGY