MicroRNA-124-3p regulates cell proliferation, invasion, apoptosis, and bioenergetics by targeting PIM1 in astrocytoma

Pim1 kinase promotes angiogenesis through phosphorylation of endothelial nitric oxide synthase at Ser-633

(2015) Ming Chen et al.   CARDIOVASCULAR RESEARCH

miR-124 exerts tumor suppressive functions on the cell proliferation, motility and angiogenesis of bladder cancer by fine-tuning UHRF1

(2015) Xinsheng Wang et al.   FEBS Journal

Gap Junctions Enhance the Antiproliferative Effect of MicroRNA-124-3p in Glioblastoma Cells

(2015) Zhang Suzhi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

miR-495 Mediates Metabolic Shift in Glioma Cells via Targeting Glut1

(2015) Sheng Nie et al.   JOURNAL OF CRANIOFACIAL SURGERY

An updated role of microRNA-124 in central nervous system disorders: a review

(2015) Yang Sun et al.   Frontiers in Cellular Neuroscience

PIM1 regulates glycolysis and promotes tumor progression in hepatocellular carcinoma

(2015) Carmen Oi-ning Leung et al.   Oncotarget

Reductions in the expression of miR-124-3p, miR-128-1, and miR-221-3p in pediatric astrocytomas are related to high-grade supratentorial, and recurrent tumors in Mexican children

(2014) Pilar Eguía-Aguilar et al.   CHILDS NERVOUS SYSTEM

MicroRNA-7 directly targets insulin-like growth factor 1 receptor to inhibit cellular growth and glucose metabolism in gliomas

(2014) Bo Wang et al.   Diagnostic Pathology

PIM kinases: an overview in tumors and recent advances in pancreatic cancer

(2014) Jianwei Xu et al.   Future Oncology

The Pim-1 Protein Kinase Is an Important Regulator of MET Receptor Tyrosine Kinase Levels and Signaling

(2014) B. Cen et al.   MOLECULAR AND CELLULAR BIOLOGY

MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras

(2014) Zhumei Shi et al.   NEURO-ONCOLOGY

Downregulation of microRNA-124 predicts poor prognosis in glioma patients

(2014) Teng Chen et al.   NEUROLOGICAL SCIENCES

MicroRNA-124 expression counteracts pro-survival stress responses in glioblastoma

(2014) V Mucaj et al.   ONCOGENE

MiR-181b-5p Downregulates NOVA1 to Suppress Proliferation, Migration and Invasion and Promote Apoptosis in Astrocytoma

(2014) Feng Zhi et al.   PLoS One

MicroRNA-486-5p targeting PIM-1 suppresses cell proliferation in breast cancer cells

(2014) Guoqiang Zhang et al.   TUMOR BIOLOGY

Decreased miR-106a inhibits glioma cell glucose uptake and proliferation by targeting SLC2A3 in GBM

(2013) Dong-Wei Dai et al.   BMC CANCER

miR-143 inhibits glycolysis and depletes stemness of glioblastoma stem-like cells

(2013) Shiguang Zhao et al.   CANCER LETTERS

The PIM Family of Serine/Threonine Kinases in Cancer

(2013) Maja Narlik-Grassow et al.   MEDICINAL RESEARCH REVIEWS

The shaping and functional consequences of the microRNA landscape in breast cancer

(2013) Heidi Dvinge et al.   NATURE

PIM1 kinase inhibitors induce radiosensitization in non-small cell lung cancer cells

(2013) Wanyeon Kim et al.   PHARMACOLOGICAL RESEARCH

microRNA-124 Inhibits Migration and Invasion by Down-Regulating ROCK1 in Glioma

(2013) Liwen An et al.   PLoS One

miR-106a-5p Inhibits the Proliferation and Migration of Astrocytoma Cells and Promotes Apoptosis by Targeting FASTK

(2013) Feng Zhi et al.   PLoS One

PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma

(2012) L Brault et al.   BRITISH JOURNAL OF CANCER

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Activated β-catenin Forces N2A Cell-derived Neurons Back to Tumor-like Neuroblasts and Positively Correlates with a Risk for Human Neuroblastoma

(2012) Feng Zhi et al.   International Journal of Biological Sciences

Loss of Brain-enriched miR-124 MicroRNA Enhances Stem-like Traits and Invasiveness of Glioma Cells

(2012) Hongping Xia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stabilization of the prostate-specific tumor suppressor NKX3.1 by the oncogenic protein kinase Pim-1 in prostate cancer cells

(2012) Achuth Padmanabhan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

CDA-2 induces cell differentiation through suppressing Twist/SLUG signaling via miR-124 in glioma

(2012) You-ke Xie et al.   JOURNAL OF NEURO-ONCOLOGY

Proto-oncogene PIM-1 is a novel estrogen receptor target associating with high grade breast tumors

(2012) Marjo Malinen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Inhibition of Pim–1 attenuates the proliferation and migration in nasopharyngeal carcinoma cells

(2012) Wei Jie et al.   Asian Pacific Journal of Tropical Medicine

Non-coding RNAs in human disease

(2011) Manel Esteller   NATURE REVIEWS GENETICS

The proto-oncogene Pim-1 is a target of miR-33a

(2011) M Thomas et al.   ONCOGENE

Exciting New Advances in Neuro-Oncology: The Avenue to a Cure for Malignant Glioma

(2010) E. G. Van Meir et al.   CA-A CANCER JOURNAL FOR CLINICIANS

PIM1 Protein Kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells

(2010) Fengxue Zhang et al.   CANCER BIOLOGY & THERAPY

The use of hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma

(2010) Feng Zhi et al.   EUROPEAN JOURNAL OF CANCER

MicroRNA-451 Regulates LKB1/AMPK Signaling and Allows Adaptation to Metabolic Stress in Glioma Cells

(2010) Jakub Godlewski et al.   MOLECULAR CELL

miR-124a Is Important for Migratory Cell Fate Transition During Gastrulation of Human Embryonic Stem Cells

(2010) Man Ryul Lee et al.   STEM CELLS

miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche

(2009) Li-Chun Cheng et al.   NATURE NEUROSCIENCE

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

(2008) Joachim Silber et al.   BMC Medicine

The 2007 WHO classification of tumors of the central nervous system – what has changed?

(2008) Audrey Rousseau et al.   CURRENT OPINION IN NEUROLOGY

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE