PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma

Pim-1 Kinase Expression Predicts Radiation Response in Squamocellular Carcinoma of Head and Neck and Is under the Control of Epidermal Growth Factor Receptor

(2015) Katriina Peltola et al.   NEOPLASIA

PIM2 inhibition as a rational therapeutic approach in B-cell lymphoma

(2011) C. Gomez-Abad et al.   BLOOD

Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma

(2011) Jonathan H. Schatz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

7,8-Dichloro-1-oxo-β-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes

(2011) Kilian Huber et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fighting Tumor Cell Survival: Advances in the Design and Evaluation of Pim Inhibitors

(2010) F. Anizon et al.   CURRENT MEDICINAL CHEMISTRY

Pim kinase inhibitors: a survey of the patent literature

(2010) Tina Morwick   EXPERT OPINION ON THERAPEUTIC PATENTS

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers

(2010) L. Brault et al.   HAEMATOLOGICA

Prognostic immunophenotypic biomarker studies in diffuse large B cell lymphoma with special emphasis on rational determination of cut-off scores

(2010) Alexandar Tzankov et al.   LEUKEMIA & LYMPHOMA

Pim-1 Kinase Protects P-Glycoprotein from Degradation and Enables Its Glycosylation and Cell Surface Expression

(2010) Y. Xie et al.   MOLECULAR PHARMACOLOGY

Activation of the Wnt Pathway Plays a Pathogenic Role in Diabetic Retinopathy in Humans and Animal Models

(2009) Ying Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

A New Immunostain Algorithm Classifies Diffuse Large B-Cell Lymphoma into Molecular Subtypes with High Accuracy

(2009) W. W.L. Choi et al.   CLINICAL CANCER RESEARCH

Coexpression of CD44 variant isoforms and receptor for hyaluronic acid−mediated motility (RHAMM, CD168) is an International Prognostic Index and C-MYC gene status−independent predictor of poor outcome in diffuse large B-cell lymphomas

(2009) Sabine Nagel et al.   EXPERIMENTAL HEMATOLOGY

BCL2 gene aberration as an IPI-independent marker for poor outcome in non-germinal-centre diffuse large B cell lymphoma

(2009) E C Obermann et al.   JOURNAL OF CLINICAL PATHOLOGY

Aberrations of the MYC gene in unselected cases of diffuse large B-cell lymphoma are rare and unpredictable by morphological or immunohistochemical assessment

(2009) E C Obermann et al.   JOURNAL OF CLINICAL PATHOLOGY

Dissection of PIM serine/threonine kinases in FLT3-ITD–induced leukemogenesis reveals PIM1 as regulator of CXCL12–CXCR4-mediated homing and migration

(2009) Rebekka Grundler et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Recurrent numerical aberrations of JAK2 and deregulation of the JAK2-STAT cascade in lymphomas

(2009) Cecile Meier et al.   MODERN PATHOLOGY

PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis

(2009) J J Gu et al.   ONCOGENE

Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma

(2009) S. Hailfinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pim Kinases Promote Cell Cycle Progression by Phosphorylating and Down-regulating p27Kip1 at the Transcriptional and Posttranscriptional Levels

(2008) D. Morishita et al.   CANCER RESEARCH

Correlation of high numbers of intratumoral FOXP3+ regulatory T cells with improved survival in germinal center-like diffuse large B-cell lymphoma, follicular lymphoma and classical Hodgkin's lymphoma

(2008) A. Tzankov et al.   HAEMATOLOGICA

Ki67 and PIM1 expression predict outcome in mantle cell lymphoma treated with high dose therapy, stem cell transplantation and rituximab: a Cancer and Leukemia Group B 59909 correlative science study

(2008) Eric D. Hsi et al.   LEUKEMIA & LYMPHOMA

Reassessment of CXCR4 Chemokine Receptor Expression in Human Normal and Neoplastic Tissues Using the Novel Rabbit Monoclonal Antibody UMB-2

(2008) Thomas Fischer et al.   PLoS One