Modification of Aβ Peptide Aggregation via Covalent Binding of a Series of Ru(III) Complexes
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Modification of Aβ Peptide Aggregation via Covalent Binding of a Series of Ru(III) Complexes
Authors
Keywords
-
Journal
Frontiers in Chemistry
Volume 7, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-12-03
DOI
10.3389/fchem.2019.00838
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- NAMI-A and KP1019/1339, Two Iconic Ruthenium Anticancer Drug Candidates Face-to-Face: A Case Story in Medicinal Inorganic Chemistry
- (2019) Enzo Alessio et al. MOLECULES
- Amyloid β oligomers constrict human capillaries in Alzheimer’s disease via signaling to pericytes
- (2019) Ross Nortley et al. SCIENCE
- A vicious cycle of β amyloid–dependent neuronal hyperactivation
- (2019) Benedikt Zott et al. SCIENCE
- Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis in the Last Decade
- (2018) Masha G. Savelieff et al. CHEMICAL REVIEWS
- The NAMI A – human ferritin system: a biophysical characterization
- (2018) Silvia Ciambellotti et al. DALTON TRANSACTIONS
- Metals, Membranes, and Amyloid-β Oligomers: Key Pieces in the Alzheimer's Disease Puzzle?
- (2018) Andrew D. Watt et al. JOURNAL OF ALZHEIMERS DISEASE
- Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases
- (2018) Claudio Soto et al. NATURE NEUROSCIENCE
- A new era for understanding amyloid structures and disease
- (2018) Matthew G. Iadanza et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Phosphorylation of the Amyloid-Beta Peptide Inhibits Zinc-Dependent Aggregation, Prevents Na,K-ATPase Inhibition, and Reduces Cerebral Plaque Deposition
- (2018) Evgeny P. Barykin et al. Frontiers in Molecular Neuroscience
- Amyloid β oligomers (AβOs) in Alzheimer’s disease
- (2017) Barbara Mroczko et al. JOURNAL OF NEURAL TRANSMISSION
- Mechanistic Insights into Tunable Metal-Mediated Hydrolysis of Amyloid-β Peptides
- (2017) Jeffrey S. Derrick et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Alzheimer's Disease: A General Introduction and Pathomechanism
- (2017) Verena H. Finder JOURNAL OF ALZHEIMERS DISEASE
- Challenges in studying the structures of metal-amyloid oligomers related to type 2 diabetes, Parkinson's disease, and Alzheimer's disease
- (2016) Vered Wineman-Fisher et al. COORDINATION CHEMISTRY REVIEWS
- Thirty Years of the Drug Candidate NAMI-A and the Myths in the Field of Ruthenium Anticancer Compounds: A Personal Perspective
- (2016) Enzo Alessio EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
- Biophysical Comparison of Soluble Amyloid-β(1–42) Protofibrils, Oligomers, and Protofilaments
- (2015) Michael R. Nichols et al. BIOCHEMISTRY
- Neurodegenerative diseases and therapeutic strategies using iron chelators
- (2015) Roberta J. Ward et al. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
- Modulation of the Aβ peptide aggregation pathway by KP1019 limits Aβ-associated neurotoxicity
- (2015) Michael R. Jones et al. Metallomics
- Methionine oxidation of amyloid peptides by peroxovanadium complexes: inhibition of fibril formation through a distinct mechanism
- (2015) Lei He et al. Metallomics
- Modulation of Amyloid-β Aggregation by Histidine-Coordinating Cobalt(III) Schiff Base Complexes
- (2014) Marie C. Heffern et al. CHEMBIOCHEM
- Ruthenium metalation of proteins: the X-ray structure of the complex formed between NAMI-A and hen egg white lysozyme
- (2014) Luigi Messori et al. DALTON TRANSACTIONS
- Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy
- (2014) Suzanne Leijen et al. INVESTIGATIONAL NEW DRUGS
- 8-Hydroxyquinoline Schiff-base compounds as antioxidants and modulators of copper-mediated Aβ peptide aggregation
- (2014) Luiza M.F. Gomes et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- NKP-1339, the first ruthenium-based anticancer drug on the edge to clinical application
- (2014) Robert Trondl et al. Chemical Science
- Untangling Amyloid-β, Tau, and Metals in Alzheimer’s Disease
- (2013) Masha G. Savelieff et al. ACS Chemical Biology
- Development of a Platinum Complex as an anti-Amyloid Agent for the Therapy of Alzheimer’s Disease
- (2013) Vijaya B. Kenche et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Structural insights into the interaction of platinum-based inhibitors with the Alzheimer's disease amyloid-β peptide
- (2013) Victor A. Streltsov et al. CHEMICAL COMMUNICATIONS
- Pt(ii) compounds interplay with Cu(ii) and Zn(ii) coordination to the amyloid-β peptide has metal specific consequences on deleterious processes associated to Alzheimer's disease
- (2013) Fabrice Collin et al. CHEMICAL COMMUNICATIONS
- Increasing the Bioavailability of RuIIIAnticancer Complexes through Hydrophobic Albumin Interactions
- (2013) Michael I. Webb et al. CHEMISTRY-A EUROPEAN JOURNAL
- Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu
- (2013) Alessandro Vergara et al. INORGANIC CHEMISTRY
- Investigating the Ruthenium Metalation of Proteins: X-ray Structure and Raman Microspectroscopy of the Complex between RNase A and AziRu
- (2013) Alessandro Vergara et al. INORGANIC CHEMISTRY
- Rational Design of a Structural Framework with Potential Use to Develop Chemical Reagents That Target and Modulate Multiple Facets of Alzheimer’s Disease
- (2013) Sanghyun Lee et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Quantification of copper binding to amyloid precursor protein domain 2 and its Caenorhabditis elegans ortholog. Implications for biological function
- (2013) Su Ling Leong et al. Metallomics
- Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein
- (2013) Ji Won Um et al. NEURON
- Promising in Vitro anti-Alzheimer Properties for a Ruthenium(III) Complex
- (2013) Luigi Messori et al. ACS Medicinal Chemistry Letters
- Therapeutic Redistribution of Metal Ions To Treat Alzheimer’s Disease
- (2012) Peter J. Crouch et al. ACCOUNTS OF CHEMICAL RESEARCH
- Facile Methodology for Monitoring Amyloid-β Fibrillization
- (2012) Nathan P. Cook et al. ACS Chemical Neuroscience
- Stability of early-stage amyloid-β(1–42) aggregation species
- (2012) Kelley A. Coalier et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Bioinorganic Chemistry of Alzheimer’s Disease
- (2012) Kasper P. Kepp CHEMICAL REVIEWS
- Diagnostic imaging of Alzheimer's disease with copper and technetium complexes
- (2012) James L. Hickey et al. COORDINATION CHEMISTRY REVIEWS
- Metal binding sites in amyloid oligomers: Complexes and mechanisms
- (2012) Yifat Miller et al. COORDINATION CHEMISTRY REVIEWS
- The art of building multifunctional metal-binding agents from basic molecular scaffolds for the potential application in neurodegenerative diseases
- (2012) Cristina Rodríguez-Rodríguez et al. COORDINATION CHEMISTRY REVIEWS
- Interference of a new cyclometallated Pt compound with Cu binding to amyloid-β peptide
- (2012) Isabelle Sasaki et al. DALTON TRANSACTIONS
- Reactivity of Diphenylpropynone Derivatives Toward Metal-Associated Amyloid-β Species
- (2012) Amit S. Pithadia et al. INORGANIC CHEMISTRY
- Hexafluoroisopropanol induces self-assembly of β-amyloid peptides into highly ordered nanostructures
- (2012) Sanjai Kumar Pachahara et al. JOURNAL OF PEPTIDE SCIENCE
- Dual-function triazole–pyridine derivatives as inhibitors of metal-induced amyloid-β aggregation
- (2012) Michael R. Jones et al. Metallomics
- NKP-1339, a first-in-class anticancer drug showing mild side effects and activity in patients suffering from advanced refractory cancer
- (2012) Robert Trondl et al. BMC Pharmacology & Toxicology
- Metal ions, Alzheimer's disease and chelation therapy
- (2011) Ana Budimir ACTA PHARMACEUTICA
- Amyloid deposits: Protection against toxic protein species?
- (2011) Sebastian Treusch et al. CELL CYCLE
- Misfolded proteins in Alzheimer's disease and type II diabetes
- (2011) Alaina S. DeToma et al. CHEMICAL SOCIETY REVIEWS
- Histidine-rich branched peptides as Cu(ii) and Zn(ii) chelators with potential therapeutic application in Alzheimer's disease
- (2011) Andrea Lakatos et al. DALTON TRANSACTIONS
- Pyridine Analogues of the Antimetastatic Ru(III) Complex NAMI-A Targeting Non-Covalent Interactions with Albumin
- (2011) Michael I. Webb et al. INORGANIC CHEMISTRY
- Iron(II) Binding to Amyloid-β, the Alzheimer’s Peptide
- (2011) Fatima Bousejra-ElGarah et al. INORGANIC CHEMISTRY
- Pharmacokinetic study of sodium trans[tetrachlorobis(1H-indazole)-ruthenate (III)]/-indazole hydrochloride (1:1.1) (FFC14A) in patients with solid tumors
- (2011) M.M. Henke et al. INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
- Molecular-Level Examination of Cu2+Binding Structure for Amyloid Fibrils of 40-Residue Alzheimer’s β by Solid-State NMR Spectroscopy
- (2011) Sudhakar Parthasarathy et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Erratum: Corrigendum: Resolving controversies on the path to Alzheimer's therapeutics
- (2011) Dennis J Selkoe NATURE MEDICINE
- Copper(II) Coordination to Amyloid β: Murine versus Human Peptide
- (2010) Hélène Eury et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The X-ray Structure of the Adduct between NAMI-A and Carbonic Anhydrase Provides Insights into the Reactivity of this Metallodrug with Proteins
- (2010) Angela Casini et al. ChemMedChem
- fac-{Ru(CO)3}2+Selectively Targets the Histidine Residues of the β-Amyloid Peptide 1-28. Implications for New Alzheimer's Disease Treatments Based on Ruthenium Complexes
- (2010) Daniela Valensin et al. INORGANIC CHEMISTRY
- Alzheimer's disease: strategies for disease modification
- (2010) Martin Citron NATURE REVIEWS DRUG DISCOVERY
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Zinc ions promote Alzheimer A aggregation via population shift of polymorphic states
- (2010) Y. Miller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alzheimer's Disease: From Pathology to Therapeutic Approaches
- (2009) Roland Jakob-Roetne et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Metal binding to alpha-synuclein peptides and its contribution to toxicity
- (2009) David R. Brown BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Comparative Study of Inhibition at Multiple Stages of Amyloid- Self-Assembly Provides Mechanistic Insight
- (2009) T. J. Davis et al. MOLECULAR PHARMACOLOGY
- KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients
- (2008) Christian G. Hartinger et al. CHEMISTRY & BIODIVERSITY
- Metal-Ligand Exchange Kinetics in Platinum and Ruthenium Complexes
- (2008) By Jan Reedijk
- Platinum-based inhibitors of amyloid- as therapeutic agents for Alzheimer's disease
- (2008) K. J. Barnham et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now