Polyphyllin II inhibits liver cancer cell proliferation, migration and invasion through downregulated cofilin activity and the AKT/NF-κB pathway

Paris Saponin II inhibits colorectal carcinogenesis by regulating mitochondrial fission and NF-κB pathway

(2018) Meihong Chen et al.   PHARMACOLOGICAL RESEARCH

Paris Saponin II induced apoptosis via activation of autophagy in human lung cancer cells

(2016) Lili Zhang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Inhibition of diethylnitrosamine-induced liver cancer in rats by Rhizoma paridis saponin

(2016) Jing Liu et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Cellular functions of the ADF/cofilin family at a glance

(2016) Georgios Kanellos et al.   JOURNAL OF CELL SCIENCE

Inhibition of EZH2 via activation of SAPK/JNK and reduction of p65 and DNMT1 as a novel mechanism in inhibition of human lung cancer cells by polyphyllin I

(2016) Longmei Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Polyphyllin VII Induces an Autophagic Cell Death by Activation of the JNK Pathway and Inhibition of PI3K/AKT/mTOR Pathway in HepG2 Cells

(2016) Chao Zhang et al.   PLoS One

Sorafenib inhibits proliferation and invasion of human hepatocellular carcinoma cells via up-regulation of p53 and suppressing FoxM1

(2015) Ji-chao Wei et al.   ACTA PHARMACOLOGICA SINICA

Pennogenyl saponins induce cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells

(2015) Fang-Yi Long et al.   JOURNAL OF ETHNOPHARMACOLOGY

Polyphyllin I induced-apoptosis is enhanced by inhibition of autophagy in human hepatocellular carcinoma cells

(2015) Ya-Min Shi et al.   PHYTOMEDICINE

Anti-lung Cancer Effects of Polyphyllin VI and VII Potentially Correlate with ApoptosisIn VitroandIn Vivo

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A new agent developed by biotransformation of polyphyllin VII inhibits chemoresistance in breast cancer

(2015) Dong-Xu He et al.   Oncotarget

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Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

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Paris saponin VII inhibits metastasis by modulating matrix metalloproteinases in colorectal cancer cells

(2014) LEI FAN et al.   Molecular Medicine Reports

Antitumor pathway of Rhizoma Paridis Saponins based on the metabolic regulatory network alterations in H22 hepatocarcinoma mice

(2014) Shuli Man et al.   STEROIDS

Growth inhibition by pennogenyl saponins from Rhizoma paridis on hepatoma xenografts in nude mice

(2014) Ya-Shu Chen et al.   STEROIDS

Bufalin inhibits migration and invasion in human hepatocellular carcinoma SK-Hep1 cells through the inhibitions of NF-kB and matrix metalloproteinase-2/-9-signaling pathways

(2013) Ya-Yin Chen et al.   ENVIRONMENTAL TOXICOLOGY

Functions of cofilin in cell locomotion and invasion

(2013) Jose Javier Bravo-Cordero et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Akt activation enhances ribosomal RNA synthesis through casein kinase II and TIF-IA

(2013) L. X. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sonic hedgehog signaling pathway induces cell migration and invasion through focal adhesion kinase/AKT signaling-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9 in liver cancer

(2012) Jing-Song Chen et al.   CARCINOGENESIS

Comparative study on hemostatic, cytotoxic and hemolytic activities of different species of Paris L.

(2012) Zhen Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Pak1/LIMK1/Cofilin Pathway Contributes to Tumor Migration and Invasion in Human Non-Small Cell Lung Carcinomas and Cell Lines

(2012) Inseok Jang et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Sorafenib-Induced Hepatocellular Carcinoma Cell Death Depends on Reactive Oxygen Species Production In Vitro and In Vivo

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Paris Saponin II of Rhizoma Paridis – A novel inducer of apoptosis in human ovarian cancer cells

(2012) Xue Xiao   BioScience Trends

In Vitro Activity of Paris polyphylla Smith Against Enterovirus 71 and Coxsackievirus B3 and Its Immune Modulation

(2011) Yuan-Chuen Wang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Curcumin and Liver Cancer: A Review

(2011) Altaf S. Darvesh et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Caffeine induces matrix metalloproteinase-2 (MMP-2) and MMP-9 down-regulation in human leukemia U937 cells via Ca2+/ROS-mediated suppression of ERK/c-fos pathway and activation of p38 MAPK/c-jun pathway

(2010) Wen-Hsin Liu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Patterns of MMP-2 and MMP-9 expression in human cancer cell lines

(2009) Niedzwiecki   ONCOLOGY REPORTS

Proteomic analysis of anti-tumor effects by Rhizoma Paridis total saponin treatment in HepG2 cells

(2008) Zhi-Xiang Cheng et al.   JOURNAL OF ETHNOPHARMACOLOGY

Blebs lead the way: how to migrate without lamellipodia

(2008) Guillaume Charras et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY