Generation of Otic Lineages from Integration-Free Human-Induced Pluripotent Stem Cells Reprogrammed by mRNAs

Modeling human early otic sensory cell development with induced pluripotent stem cells

(2018) Hanae Lahlou et al.   PLoS One

mRNA-Based Genetic Reprogramming

(2018) Luigi Warren et al.   MOLECULAR THERAPY

An Insight into DNA-free Reprogramming Approaches to Generate Integration-free Induced Pluripotent Stem Cells for Prospective Biomedical Applications

(2018) Manash P. Borgohain et al.   Stem Cell Reviews and Reports

Generation of inner ear organoids containing functional hair cells from human pluripotent stem cells

(2017) Karl R Koehler et al.   NATURE BIOTECHNOLOGY

Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration

(2017) Michiko Mandai et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cochlear Cell Modeling Using Disease-Specific iPSCs Unveils a Degenerative Phenotype and Suggests Treatments for Congenital Progressive Hearing Loss

(2017) Makoto Hosoya et al.   Cell Reports

Synthetically modified mRNA for efficient and fast human iPS cell generation and direct transdifferentiation to myoblasts

(2016) David Preskey et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effects of genetic correction on the differentiation of hair cell-like cells from iPSCs with MYO15A mutation

(2016) J-R Chen et al.   CELL DEATH AND DIFFERENTIATION

Induction of differentiation of human embryonic stem cells into functional hair-cell-like cells in the absence of stromal cells

(2016) Jie Ding et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

In Vitro Differentiation of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells into Auditory Hair Cells and Neurons

(2016) Kicheol Kil et al.   Journal of International Advanced Otology

Single-cell analysis delineates a trajectory toward the human early otic lineage

(2016) Megan Ealy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apoptosis and failure of checkpoint kinase 1 activation in human induced pluripotent stem cells under replication stress

(2016) Joelle A. Desmarais et al.   Stem Cell Research & Therapy

Genetic Correction of Induced Pluripotent Stem Cells From a Deaf Patient With MYO7A Mutation Results in Morphologic and Functional Recovery of the Derived Hair Cell-Like Cells

(2016) Zi-Hua Tang et al.   Stem Cells Translational Medicine

Innervation of Cochlear Hair Cells by Human Induced Pluripotent Stem Cell-Derived NeuronsIn Vitro

(2016) Niliksha Gunewardene et al.   Stem Cells International

Current advances in the generation of human iPS cells: implications in cell-based regenerative medicine

(2015) Ana Revilla et al.   Journal of Tissue Engineering and Regenerative Medicine

Limited hair cell induction from human induced pluripotent stem cells using a simple stepwise method

(2015) Hiroe Ohnishi et al.   NEUROSCIENCE LETTERS

Inner Ear Hair Cell-Like Cells from Human Embryonic Stem Cells

(2014) Mohammad Ronaghi et al.   STEM CELLS AND DEVELOPMENT

Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture

(2013) Karl R. Koehler et al.   NATURE

Restoration of auditory evoked responses by human ES-cell-derived otic progenitors

(2012) Wei Chen et al.   NATURE

Generation of inner ear sensory cells from bone marrow-derived human mesenchymal stem cells

(2012) M Beatriz Durán Alonso et al.   Regenerative Medicine

Inner ear progenitor cells can be generated in vitro from human bone marrow mesenchymal stem cells

(2012) Sarah L Boddy et al.   Regenerative Medicine

Chemically defined conditions for human iPSC derivation and culture

(2011) Guokai Chen et al.   NATURE METHODS

Methods for making induced pluripotent stem cells: reprogramming à la carte

(2011) Federico González et al.   NATURE REVIEWS GENETICS

Mechanosensitive Hair Cell-like Cells from Embryonic and Induced Pluripotent Stem Cells

(2010) Kazuo Oshima et al.   CELL

Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA

(2010) Luigi Warren et al.   Cell Stem Cell

Embryonic and adult stem cell therapy

(2010) Anne C. Brignier et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences

(2009) J. Yu et al.   SCIENCE

Human Fetal Auditory Stem Cells Can Be Expanded In Vitro and Differentiate Into Functional Auditory Neurons and Hair Cell-Like Cells

(2009) Wei Chen et al.   STEM CELLS